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Determination of aristolochic acid by capillary zone electrophoresis
Kvasnička František +3 more
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Short-term toxicity of aristolochic acid, aristolochic acid-I and aristolochic acid-II in rats
Food and Chemical Toxicology, 2008We compared the short-term toxicity of toxic components of aristolochic acid in rats. Twenty-four female Wistar rats were divided into 4 groups and treated orally every 3-days with 10 mg/kg each of aristolochic acid, aristolochic acid-I and aristolochic acid-II for 19 days.
Yen-Hung, Yeh +3 more
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Biosynthesis of Aristolochic Acid
European Journal of Biochemistry, 1967Some Aristolochia species were investigated for the presence of aristolochic acid and magnoflorine. In all cases these two compounds were found in the roots and rhizomes of the plants,[4‐14C]‐Tetrahydropapaverine · HCl feeding to Aristolochia sipho gave no radioactive aristolochic acid I.
H R, Schütte, U, Orban, K, Mothes
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Aristolochic Acids in Aristolochia chilensis
Planta Medica, 1982The major components of the acid fraction of the leaves and tender stems of Aristolochia chilensis Miers are aristolochic acids I and Ia. Aristolochic acid Ia has been isolated from plant material for the fïrst time, and its PMR spectrum is discussed.
A, Urzúa +3 more
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Biosynthesis of aristolochic acid
Journal of the Chemical Society, Perkin Transactions 1, 1982The incorporation of tyrosine, (3,4-dihydroxyphenyl)alanine, nororientaline, orientaline, prestephanine, and stephanine into aristolochic acid in Aristolochic bracteata has been studied; specific utilisation of nororientaline has been demonstrated.
Vidur Sharma +3 more
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Biosynthesis of aristolochic acid
Canadian Journal of Chemistry, 1969The biosynthesis of aristolochic acid-1 (1) was studied in Aristolochia sipho. Tyrosine, dopa, dopamine, and noradrenaline serve as specific precursors. The nitro group of aristolochic acid is derived from the amino group of tyrosine. The aristolochic acids are yet another group of natural products related to norlaudanosoline.
F. Comer, H. P. Tiwari, I. D. Spenser
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Mass Spectrometry of Aristolochic Acids
Journal of Natural Products, 1983This work was supported by grants from DICYT (USACH) and the Organization of American States.
Eckhardt, Gert +2 more
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Biotransformation and Toxicities of Aristolochic Acids
2020Environmental and iatrogenic exposures contribute significantly to human diseases, including cancer. The list of known human carcinogens has recently been extended by the addition of aristolochic acids (AAs). AAs occur primarily in Aristolochia herbs, which are used extensively in folk medicines, including Traditional Chinese Medicine. Ingestion of AAs
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Identification of aristolochic acid in Chinese herbs
The Lancet, 1994Letter ; info:eu-repo/semantics ...
Vanhaelen, Maurice +3 more
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Fluorometric and GLC Analyses of Aristolochic Acid
Journal of Pharmaceutical Sciences, 1975Aristolochic acid is a natural product with possible implication in Balkan endemic nephropathy. A convenient fluorometric assay for the compound is described based on reduction to the lactam and measurement of the intensity of fluorescence. The limit of sensitivity was 0.05 mug/ml.
K V, Rao, Y, Tanrikut, K, Killion
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