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Determination of aristolochic acid by capillary zone electrophoresis

open access: yesOpen Chemistry, 2004
Kvasnička František   +3 more
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Short-term toxicity of aristolochic acid, aristolochic acid-I and aristolochic acid-II in rats

Food and Chemical Toxicology, 2008
We compared the short-term toxicity of toxic components of aristolochic acid in rats. Twenty-four female Wistar rats were divided into 4 groups and treated orally every 3-days with 10 mg/kg each of aristolochic acid, aristolochic acid-I and aristolochic acid-II for 19 days.
Yen-Hung, Yeh   +3 more
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Biosynthesis of Aristolochic Acid

European Journal of Biochemistry, 1967
Some Aristolochia species were investigated for the presence of aristolochic acid and magnoflorine. In all cases these two compounds were found in the roots and rhizomes of the plants,[4‐14C]‐Tetrahydropapaverine · HCl feeding to Aristolochia sipho gave no radioactive aristolochic acid I.
H R, Schütte, U, Orban, K, Mothes
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Aristolochic Acids in Aristolochia chilensis

Planta Medica, 1982
The major components of the acid fraction of the leaves and tender stems of Aristolochia chilensis Miers are aristolochic acids I and Ia. Aristolochic acid Ia has been isolated from plant material for the fïrst time, and its PMR spectrum is discussed.
A, Urzúa   +3 more
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Biosynthesis of aristolochic acid

Journal of the Chemical Society, Perkin Transactions 1, 1982
The incorporation of tyrosine, (3,4-dihydroxyphenyl)alanine, nororientaline, orientaline, prestephanine, and stephanine into aristolochic acid in Aristolochic bracteata has been studied; specific utilisation of nororientaline has been demonstrated.
Vidur Sharma   +3 more
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Biosynthesis of aristolochic acid

Canadian Journal of Chemistry, 1969
The biosynthesis of aristolochic acid-1 (1) was studied in Aristolochia sipho. Tyrosine, dopa, dopamine, and noradrenaline serve as specific precursors. The nitro group of aristolochic acid is derived from the amino group of tyrosine. The aristolochic acids are yet another group of natural products related to norlaudanosoline.
F. Comer, H. P. Tiwari, I. D. Spenser
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Mass Spectrometry of Aristolochic Acids

Journal of Natural Products, 1983
This work was supported by grants from DICYT (USACH) and the Organization of American States.
Eckhardt, Gert   +2 more
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Biotransformation and Toxicities of Aristolochic Acids

2020
Environmental and iatrogenic exposures contribute significantly to human diseases, including cancer. The list of known human carcinogens has recently been extended by the addition of aristolochic acids (AAs). AAs occur primarily in Aristolochia herbs, which are used extensively in folk medicines, including Traditional Chinese Medicine. Ingestion of AAs
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Identification of aristolochic acid in Chinese herbs

The Lancet, 1994
Letter ; info:eu-repo/semantics ...
Vanhaelen, Maurice   +3 more
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Fluorometric and GLC Analyses of Aristolochic Acid

Journal of Pharmaceutical Sciences, 1975
Aristolochic acid is a natural product with possible implication in Balkan endemic nephropathy. A convenient fluorometric assay for the compound is described based on reduction to the lactam and measurement of the intensity of fluorescence. The limit of sensitivity was 0.05 mug/ml.
K V, Rao, Y, Tanrikut, K, Killion
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