Results 141 to 150 of about 2,520,275 (163)

TNF- α from the Proximal Nephron Exacerbates Aristolochic Acid Nephropathy. [PDF]

Kidney360
Wen Y, Lu X, Privratsky JR, Ren J, Ali S, Yang B, Rudemiller NP, Zhang J, Nedospasov SA, Crowley SD.   +9 more
europepmc   +1 more source

Identification and analysis of differently expressed transcription factors in aristolochic acid nephropathy. [PDF]

Environ Health Prev Med
Wu YF, Tang ZY, Deng YX, Liu K, Gu XR, Zhou GL, Huang YJ, Lin XQ, Zhou LY, Zuo XC.   +9 more
europepmc   +1 more source

In vivo targeted-imaging of mitochondrial acidification in an aristolochic acid I-induced nephrotoxicity mouse model by a fluorescent/photoacoustic bimodal probe. [PDF]

Mater Today Bio
Xu L, Chen L, Liu H, Chen X, Zhang S.
europepmc   +1 more source

PSTPIP2 ameliorates aristolochic acid nephropathy by suppressing interleukin-19-mediated neutrophil extracellular trap formation. [PDF]

Elife
Du C, Xu C, Jia P, Cai N, Zhang Z, Meng W, Chen L, Zhou Z, Wang Q, Feng R, Li J, Meng X, Huang C, Ma T.   +13 more
europepmc   +1 more source

Hepatic cytochrome P450s metabolize aristolochic acid and reduce its kidney toxicity [PDF]

Kidney International, 2008
Cytochrome P450s metabolize the naturally occurring nephrotoxin aristolochic acid. Using liver-specific cytochrome P450 reductase-null mice we found that a low but lethal dose of aristolochic acid I was ineffective in wild-type mice. Induction of hepatic
Xiang Xue
exaly   +2 more sources

Probenecid prevents acute tubular necrosis in a mouse model of aristolochic acid nephropathy [PDF]

Kidney International, 2012
Experimental aristolochic acid nephropathy is characterized by early tubulointerstitial injury followed by fibrosis, reproducing chronic lesions seen in humans.
Joelle Nortier, Volker M. Arlt, Marie-Helene ANTOINE   +2 more
exaly   +2 more sources

Aristolactam-DNA adducts are a biomarker of environmental exposure to aristolochic acid [PDF]

Kidney International, 2012
Endemic (Balkan) nephropathy is a chronic tubulointerstitial disease frequently accompanied by urothelial cell carcinomas of the upper urinary tract.
Robert J Turesky, Bojan Jelaković, Kathleen G Dickman   +2 more
exaly   +2 more sources

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Co-Exposure to Aristolochic Acids I and II Increases DNA Adduct Formation Responsible for Aristolochic Acid I-Mediated Carcinogenicity in Rats

International Journal of Molecular Sciences, 2021
Marie Stiborová, Petr Hodek, Volker M. Arlt   +2 more
exaly  

Mitochondrial dysfunction is involved in aristolochic acid I-induced apoptosis in renal proximal tubular epithelial cells

Human and Experimental Toxicology, 2020
Xiao Yang, Xiao Yang
exaly  

Short-term toxicity of aristolochic acid, aristolochic acid-I and aristolochic acid-II in rats

Food and Chemical Toxicology, 2008
Yen-Hung Yeh, Deng-Fwu Hwang, Ya-Ting Lee   +2 more
exaly