Results 51 to 60 of about 291,608 (311)

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

The Activities of NKVD Forces of Rear Defence Fronts in Lithuania (1944–1945)

Genocidas ir Rezistencija, 1997
This is an article on the NKVD army of the 3rd Belarusian background front and is a fragment of a paper on those Soviet military occupying forces (rifle regiments, border regiments and detachments, destruction battalions made up of collaborators) that ...
Juozas Starkauskas
doaj   +1 more source

Legal Aspects of Armed Resistance

Teka Komisji Prawniczej PAN Oddział w Lublinie, 2017
The aim of this article is to analyse legal aspects of armed resistance movements with a focus on the legal status of the partisan and the legal nature of a civil war. In the light of the norms of international law, both the status of a partisan and the nature of a civil war is, from the point of view of this analysis, connected with, inter alia ...
openaire   +1 more source

Empowering the Democratic Resistance in Syria [PDF]

, 2013
When the peaceful uprising in Syria started in spring 2011 turned into an armed resistance after a few months in the face of savage repression by the Assad regime. Since then, the activists who picked up arms became dependent on support in money and arms
Felix Legrand
core  

Explaining Myanmar's Regime Transition: The Periphery is Central [PDF]

, 2014
In 2010, Myanmar (Burma) held its first elections after 22 years of direct military rule. Few compelling explanations for this regime transition have emerged.
Brooker Paul, Callahan Mary, Callahan Mary, Fink Christina, Hewison Kevin, Huntington Samuel P., Jessop Bob, Kyi Khin Maung, Lambrecht Curtis, Lee Jones, MacLean Ken, May R. J., McCoy Alfred, Nordlinger Eric A., O'Donnell Guillermo, Pedersen Morten B., Rouquié Alain, Sadan Mandy, Schedler Andreas, Selth Andrew, Seng Koh Kim, Skidmore Monique, Smith Martin, Smith Martin, Steinberg David I, Taylor Robert H., Tin Maung Maung Than, TNI   +27 more
core   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

South Kivu: identity, territory, and power in the eastern Congo [PDF]

, 2013
This Usalama report by Koen Vlassenroot outlines the historical dynamics behind the armed movements in South Kivu, focusing on the period before and leading up to the First Congo War.
Vlassenroot, Koen
core  

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

A role played by the All-Union Communist Party (Bolsheviks) Central Committee Bureau for Lithuania in suppressing resistance of partisans (November 1944–March 1947)

Genocidas ir Rezistencija, 2017
The article examines the role of one of the main administrative institutions of the Soviet occupation, the All-Union Communist Party (Bolsheviks) Central Committee Bureau for Lithuanian Affairs, in organising the suppression of the anti-Soviet ...
Mindaugas Pocius
doaj   +1 more source

On Government-industry Nexus and Indigenous Armed Resistance [PDF]

Defence and Peace Economics, 2017
AbstractThis paper proposes a simple game-theoretic framework for analyzing the relationship between the government, industry and indigenous community, especially in the context of mounting violence surrounding displacement of indigenous communities by governments for the purposes of commercial use of their habitat.
openaire   +1 more source