Results 81 to 90 of about 15,388,388 (297)

Epidemiological characteristics of medial tibial plateau fractures and effects of two surgical methods for Wahlquist type C fractures

Journal of Orthopaedic Reports
Objective: To explore the epidemiological characteristics of medial tibial plateau fractures and compare the clinical outcomes of two surgical methods for Wahlquist type C fractures.
Xu Yunqin, Tang Yong, Deng Pan, Yao Yourong, Wei Qiangqiang, Wang Jianmin   +5 more
doaj   +1 more source

The Missing Tax Benefit of Donor-Advised Funds [PDF]

, 2016
The second largest charitable organization in the country in terms of annual money raised is not the Red Cross, the Salvation Army, or the YMCA— it’s Fidelity Investments. The sixth largest is Charles Schwab Corp. Vanguard Group Inc. is No. 10.
Brooks, John R.
core   +1 more source

SETD1A Regulates Glycolysis and Senescence of Nucleus Pulposus Cells via H3K4me3–HELZ2/PPARα‐HIF1α Axis to Drive Intervertebral Disc Degeneration

Advanced Science, EarlyView.
SETD1A is a key epigenetic regulator in NPCs during IDD. In normal NPCs, it sustains H3K4me3–HELZ2/PPARα–HIF1α signaling to maintain glycolytic energy metabolism and proliferation. In degenerated NPCs, reduced SETD1A disrupts this axis, impairing glycolysis and accelerating senescence, highlighting a promising therapeutic target for IDD.
Jiawei Fu, Xue Leng, Jiang Long, Zhengao Liao, Xiaoqin An, Xuezheng Ai, Dan Long, Changqing Li, Bo Huang, Yue Zhou, Shiwu Dong, Chencheng Feng   +11 more
wiley   +1 more source

Land Use and Remedy Selection: Experience from the Field — The Fort Ord Site [PDF]

In September of 1994, the Army closed the Fort Ord Military Reservation, a Superfund site of some 28,000 acres located in Monterey County, California. Under the Base Closure and Realignment Act, nearly all of this land will be transferred to federal and ...
Hersh, Robert, Wernstedt, Kris
core  

Decoding Undesirable Inflammatory Responses of Nucleic Acid‐Delivering Lipid Nanoparticles

Advanced Science, EarlyView.
Lipid nanoparticles (LNPs) enable efficient nucleic acid delivery, but their immunogenicity is a double‐edged sword. This review explores LNP‐driven innate and adaptive immunity, covering lipid components, endosomal escape, and nucleic acid sensing.
Ruimin Hu, Yin Dou, Chenwen Li, Yuying Mu, Huiying Ouyang, Wenhao Shen, Jianxiang Zhang   +6 more
wiley   +1 more source

Cowards and Heroes: Group Loyalty in the American Civil War [PDF]

What motivated men to risk death in the most horrific war in U.S. history when pay was low and irregular and military punishment strategies were weak? In such a situation creating group loyalty by promoting social capital is of paramount importance and ...
Dora L. Costa, Matthew E. Kahn
core  

All-ages Movement Project - Project Report [PDF]

, 2006
The All-ages Movement Project (AMP) is aiming to find and better understand youth-run cultural organizations focused on music in the United States. For four months, AMP has been exploring these organizations' social and political significance and the ...
Shannon Stewart
core  

The RNA‐Binding Protein PARN Remodeled 3′ UTR Structure Defines Poly(A)‐Loading Sites to Mediate Immunoglobulin Homeostasis

Advanced Science, EarlyView.
ABSTRACT Class Switch Recombination (CSR) is essential for generating high‐affinity antibody isotypes from IgM during adaptive humoral responses. Despite well‐established roles for various transcription factors, whether CSR is subject to dedicated post‐transcriptional control represents a significant gap in knowledge.
Siyuan Sun, Chen Yang, Xiaoyu Wang, Naijing Hu, Shengyao Zhang, Xinchun Li, Yu Chen, Jianan Zhai, Xiangfeng Tang, Wei Lu, Chenxu Lu, Changchang Cao, Weiru Yu, Wenhao Wu, Xiaonan Nie, Fengchao Wang, Bing Fang, Fazheng Ren, Yixuan Li, Juan Chen   +19 more
wiley   +1 more source

Using microwave ablation in combination with curettage and reconstruction with a vascularized iliac bone graft guided by a three-dimensional printed model for the treatment of a grade III talar giant cell tumor: a case report

BMC Musculoskeletal Disorders
Background Juxta-articular giant cell tumors in the talus are very rare and pose a special problem for reconstruction after aggressive tumor curettage.
ZhaoHui Pan, YuXiang Zhao, XingHua Ye, JianBo Wang, Pingping Jiang   +4 more
doaj   +1 more source

Supramolecular Assembly of Stepped‐Persistent ROS Nanogenerator for Sustained Tumor Immunotherapy

Advanced Science, EarlyView.
ROS catalytic systems often fail to achieve both effective tumor elimination and persistent immune activation due to their monotonous ROS production profiles. A stepped‐persistent ROS nanogenerator was developed by supramolecularly assembling multiple ROS generation modules within a nanofiber structure to simultaneously extend ROS generation duration ...
Zhenqiang Wang, Ming Qin, Wenjing Lai, Shiwen Chen, Fengling Wang, Dandan Xie, Maohua Chen, Changpeng Hu, Kui Wang, Rong Zhang, Guobing Li   +10 more
wiley   +1 more source