Results 171 to 180 of about 47,644 (242)

Persistent Secondary Hypogonadism Following Chronic Opioid and Anabolic Steroid Exposure: A Case Report of Long-Term Testosterone Replacement Therapy and Its Complications. [PDF]

Cureus
Hollis E, Neamtu R, Sandoval A, Bruce K.
europepmc   +1 more source

Effects of short‐course preoperative endocrine therapy on tumour morphology and immunohistochemical profile in oestrogen receptor‐positive, HER2‐negative breast cancer

Histopathology, Volume 89, Issue 4, Page 670-686, October 2026.
Short‐course preoperative endocrine therapy induces histopathological and immunophenotypic changes in oestrogen receptor‐positive, HER2‐negative breast cancer. Proliferative response is independently associated with baseline genomic risk (MammaPrint) and progesterone receptor expression.
Claudia Grosse, Alexandra Grosse, Petar Noack, Caroline Ines Preuss, Heike Kathleen Schwarz, Bruno Schneeweiss, Thomas Gitter, Peter Schrenk, Rupert Langer   +8 more
wiley   +1 more source

Mammary Adipocyte Size, Obesity-Related Breast Adipose Tissue Dysfunction, and Breast Cancer: A Systematic Review and Meta-Analysis. [PDF]

Cancers (Basel)
Badre O, Chang SL, Abdous B, Lemieux J, Durocher F, Tchernof A, Diorio C.   +6 more
europepmc   +1 more source

Aromatase and Aromatase Inhibitors in Breast Cancer Treatment

Journal of Current Pharma Research, 2018
Prafulla M Sabale ., Vidya P. Sabale ., Lata C. Potey .   +2 more
openaire   +1 more source

Divergent effects of hyperandrogenemia on the female reproductive neuroendocrine axis under different physiological conditions

Journal of Neuroendocrinology, Volume 38, Issue 10, October 2026.
Abstract The hypothalamic–pituitary–gonadal (HPG) axis coordinates reproductive function and incorporates gonadal sex steroid feedback to regulate gonadotropin secretion in a homeostatic manner. In females, ovarian estrogens and progestins act as the primary negative feedback signals to suppress luteinizing hormone (LH) release, whereas in males ...
Lillian Rose, Alexander S. Kauffman
wiley   +1 more source

Metabolic Endotoxemia Amplifies Estrogen Signaling Through Stromal Crosstalk in Obesity-Associated Breast Cancer. [PDF]

Int J Mol Sci
Drai E, Nahmias Blank D, Hermano E, Yifrach A, Chen O, Maimon O, Popovtzer A, Peretz T, Meirovitz A, Elkin M.   +9 more
europepmc   +1 more source

Long‐term endurance running training and testosterone daily variation in ageing men; a comparative cross‐sectional study

Experimental Physiology, Volume 111, Issue 10, Page 4620-4635, 1 October 2026.
Abstract The aim of this study was to assess the relationship between long‐term endurance running training and daily variation in testosterone, which is known to diminish during ageing, in a comparative, cross‐sectional study. We recruited 45 male participants into four groups [young athletes (YA), young sedentary (YS), master athletes (MA) and elderly
Barbora Bartko, Ľudmila Oreská, Gabriel Buzgó, Genc Berisha, Valentína Zemaníková, Monika Okuliarová, Michal Zeman, Milan Sedliak   +7 more
wiley   +1 more source

Vertebral Fractures Beyond Bone Density in Breast Cancer: A Real-World Study of Endocrine Therapy and FRAX Reclassification. [PDF]

J Clin Med
Kollár R, Leel-Őssy T, Szigeti E, Dank M, Hosszú É, Horváth C, Mészáros S.   +6 more
europepmc   +1 more source

(S)‐Pyrrolo[1,2‐a]pyrazine‐3‐carboxamide Analogs as Dual Akt/JNK Modulators With Antiproliferative Effects in MDA‐MB‐468 Cells

ChemMedChem, Volume 21, Issue 17, 14 September 2026.
Among 30 synthesized pyrrolo[1,2‐a]pyrazine analogs, compounds B1 and B3 showed strong and selective cytotoxicity toward TNBC cells, inducing apoptosis through Akt suppression and JNK activation. Triple‐negative breast cancer (TNBC) remains a major clinical challenge due to the absence of effective targeted therapies.
Narges Hosseininasab, Sou Hyun Kim, Ye‐Mi Kwon, Jungjin Park, Chanhyun Jung, Kwanghee Lee, Beom‐Jun Wi, Su‐Jin Yoo, Soonsil Hyun, Young‐Suk Jung, Jae‐Hwan Kwak   +10 more
wiley   +1 more source