Results 71 to 80 of about 597,754 (265)

Bioengineered Exosome‐Loaded Immunomodulatory Bioadhesive Spray Reverses Liver Fibrosis and Metabolic Dysfunction That Triggers Beneficial Gut‐Liver Crosstalk in Chronic Fatty Liver Disease

Advanced Science, EarlyView.
Umbilical cord stem cell‐derived exosomes encapsulated in an immunomodulatory bioadhesive hydrogel spray enable localized therapy, sustained vesicle delivery, macrophage polarization, suppress systemic inflammation, and mitigate glucose and insulin homeostasis impairments in MAFLD.
Triya Saha, Ayushi Mairal, Shreya Mehrotra, Shiv K. Sarin, Ashok Kumar   +4 more
wiley   +1 more source

Mechanochemical Piezoelectric Catalysis: Advancing the Hydrogenation of Alkenes

Advanced Science, EarlyView.
This study presents mechanochemical piezoelectric catalysis for alkene hydrogenation, eliminating the need for transition metals, H2, and solvents. The method effectively hydrogenates diverse activated and unactivated alkenes and shows potential for modifying bioactive molecules in pharmaceuticals.
Zixi Ai, Mengting Liu, Xiaohong Wang, Xiaochun He, Xuemei Zhang, Zhong Lian   +5 more
wiley   +1 more source

Pd‐Catalyzed Asymmetric Dearomative Heck/Tsuji‐Trost Difunctionalization of Naphthalenes

Advanced Science, EarlyView.
We have developed a palladium‐catalyzed asymmetric dearomative Heck/Tsuji‐Trost 1,4‐difunctionalization reaction of naphthalenes, affording 4‐aminospirocyclohexene oxindole products bearing two remote chiral centers. Through the effect of the newly designed chiral sulfinamide phosphine ligand with large steric hindrance, side reactions are inhibited ...
Long‐Ling Ma, Bing Xu, Junliang Zhang, Zhan‐Ming Zhang   +3 more
wiley   +1 more source

How Does Nucleophilic Aromatic Substitution in Nitroarenes Really Proceed: General Mechanism

, 2017
On the basis of previously published experimental studies and ab initio calculations, a general corrected mechanism of nucleophilic aromatic substitution was formulated.
Mieczysław Mąkosza
core   +1 more source

Charting the Future of Stereoselective Carbohydrate Synthesis: The Essential Role of Cross‐Disciplinary Innovation

Advanced Science, EarlyView.
Cross‐disciplinary endeavors are blossoming across the broad chemical sciences. This perspective provides a glimpse into the rewarding interdisciplinary journey taken by the Charles Loh research group in pioneering the σ‐hole based catalytic glycosylation strategy.
Charles C. J. Loh
wiley   +1 more source

Organocatalyzed synthesis of fluorinated poly(aryl thioethers)

Nature Communications, 2017
Fluorinated poly(aryl thioethers), unlike their poly(aryl ethers) counterparts, have received little attention despite excellent physical properties displayed by many polysulfides.
Nathaniel H. Park, Gabriel dos Passos Gomes, Mareva Fevre, Gavin O. Jones, Igor V. Alabugin, James L. Hedrick   +5 more
doaj   +1 more source

Hydrogen‐Bond Enabled Phosphite Based Intrinsic Flame‐Retardant Solid‐Solid Phase Change Materials Using Catalyst/Solvent‐Free Multi‐Component Reaction for Battery Thermal Management

Advanced Science, EarlyView.
The phosphite group endows intrinsic flame retardancy, while the P = O bond enhances intermolecular interactions to realize solid‐solid phase transition. Battery thermal management tests show the materials extend the safe working time of lithium‐ion batteries by 200%. Cone calorimeter tests indicate a 14s delay in ignition time, and reductions of 37.6%,
Changhui Liu, Guangyuan Liang, Yuanzheng Liu, Jiantang Gao, Zeyang Li, Lin Huang, Jiateng Zhao, Junbing Xiao, Xiaoxing Zhong, Jun (Joelle) Wang   +9 more
wiley   +1 more source

Late-stage adenine N6-alkylation of nucleos(t)ides and oligonucleotides via photoredox and copper co-catalytic decarboxylative C(sp3)–N coupling

Nature Communications
Nucleosi(ti)des and nucleic acids with N6 modified adenosine play an important role in the areas of disease diagnosis and treatment, biological chemistry, as well as nanotechnology.
Ruoqian Xie, Guolan Xiao, Wanlu Li, Wenhao Luochen, Madiha Butt, Yingchuan Que, Xiaorong Li, Yangyan Li, Litao Sun, Gang Chen   +9 more
doaj   +1 more source

4,4’-Bis(4-octylphenoxy)-2,2’-bipyridine

Molbank, 2009
4,4’-Bis(4-octylphenoxy)-2,2’-bipyridine which can be used in complexes of ruthenium was synthesized. This ligand bears a long chain for the purpose of increasing the solubility of the final complex.
Zhen-Ting Du, Jun-Ru Wang, Ru Liu, Yan Xu   +3 more
doaj   +1 more source

Cinetica da reação de aminolise de 2, 2, 2 - tricloro - 1 - ariletanonas [PDF]

, 1988
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciencias Fisicas e MatematicasA cinética da aminólise de 2,2,2-tricloro-1-ariletanonas (1), a 25oC mostra que a ordem da reação em relação às aminas depende do solvente usado ...
Druzian, Janice Izabel
core