Trifluoromethylsulfide Anion: Generation and Reaction with Pentafluoropyridine [PDF]
CHIMIA, 1985 The anion F3CS⊖, generated from thiocarbonyl difluoride 1 and alkali metal fluorides, reacts with pentafluoropyridine 2 to give high yield of 2,3,5,6-tetrafluoro-4-trifluoromethylthiopyridine 3.
Wojciech Dmowski, Alois Haas
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Perfluorination of Aromatic Compounds Reinforce Their van der Waals Interactions with Rare Gases: The Rotational Spectrum of Pentafluoropyridine-Ne [PDF]
Molecules, 2021 The rotational spectrum of the pentafluoropyridine-Ne complex, generated in a supersonic jet, has been investigated using chirped-pulse microwave Fourier transform spectroscopy in the 2–8 GHz range.
Alberto Macario +3 more
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A protocol for the gram-scale synthesis of polyfluoroaryl sulfides via an SNAr step [PDF]
STAR Protocols, 2023 Summary: Polyfluoroaryl sulfide is one of the prevalent motifs ubiquitous in materials and pharmaceutical chemistry. We herein describe a simple yet efficient procedure for their synthesis from readily available thiols and polyfluoroarenes via an SNAr ...
Cheng-Lin Chan +2 more
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Speciation-Controlled C-F Bond Functionalization Enabled by Zwitterionic Pnictinidenes. [PDF]
Angew Chem Int Ed EnglZwitterionic pnictinidenes turn C–F activation into C–X bond construction, enabling broad defluorinative functionalization of polyfluoro(hetero)arenes under mild conditions. Rather than following a metallomimetic Sb(I)/Sb(III) redox turnover, catalysis is redirected by ligand scrambling into a redox‐neutral manifold, revealing catalyst speciation as a ...
Sánchez-Sordo I +4 more
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Molecular engineering of bistetrafluoropyridine aryl ethers: a general platform for stable and programmable amorphous organic solids [PDF]
RSC AdvancesWe report a highly efficient strategy for the synthesis of a novel class of amorphous, small-molecule organic glass formers (MOGs) derived from pentafluoropyridine (PFP). Utilizing a single-step, atom-economical, and highly scalable nucleophilic aromatic
Nathan J. Weeks +2 more
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Ring Strain-Promoted Activation of Pyridines by a Saturated BSi<sub>2</sub> Cycle. [PDF]
Angew Chem Int Ed EnglWe report a highly strained boratadisilirane with the elusive anionic BSi2 ring motif. Cleavage of the Si─Si bond during reactions with pyridine derivatives activates them in three different ways: 1) for pyridine itself selective ortho‐CH activation and concomitant hydrogen transfer to a second pyridine molecule occurs, 2) with dimethylaminopyridine ...
Parvin N +5 more
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Chiral inheritance effect in the reactive cystine-based coassembly system [PDF]
Nature CommunicationsControlled chemical reactions in the condensed state are key steps in designing smart materials. Due to the absence of diffusion and sufficient molecular collision, the reaction efficiency in the solid or aggregated state is expectedly much lower than ...
Zhuoer Wang +3 more
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Carboxylic Acid Deoxyfluorination and One-Pot Amide Bond Formation Using Pentafluoropyridine (PFP). [PDF]
Org Lett, 2021 This work describes the application of pentafluoropyridine (PFP), a cheap commercially available reagent, in the deoxyfluorination of carboxylic acids to acyl fluorides. The acyl fluorides can be formed from a range of acids under mild conditions.
Brittain WDG, Cobb SL.
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Visible-light-promoted direct desulfurization of glycosyl thiols to access C-glycosides [PDF]
Nature CommunicationsC-Glycosides are essential for the study of biological processes and the development of carbohydrate-based drugs. Despite the tremendous hurdles, glycochemists have often fantasized about the efficient, highly stereoselective synthesis of C-glycosides ...
Demeng Xie +3 more
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Zwitterionic Heavier Pnictinidenes in Redox Catalysis. [PDF]
Angew Chem Int Ed EnglZwitterionic pnictinidenes: A new class of zwitterionic heavier pnictogen species stabilized by bis(N‐heterocyclic carbene)borate ligands is reported, enabling the isolation of Sb and Bi in multiple oxidation states. These thoroughly characterized systems exhibit cationic character and engage in redox catalysis, facilitating catalytic ...
Fernando S +7 more
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