Results 91 to 100 of about 597,754 (265)

Perhalogenated pyrimidine scaffolds. Reactions of 5-chloro-2,4,6-trifluoropyrimidine with nitrogen centred nucleophiles

Beilstein Journal of Organic Chemistry, 2008
BackgroundHighly functionalised pyrimidine derivatives are of great importance to the life-science industries and there exists a need for efficient synthetic methodology that allows the synthesis of polysubstituted pyrimidine derivatives that are ...
Emma L. Parks, Graham Sandford, John A. Christopher, David D. Miller   +3 more
doaj   +1 more source

Further Successes of the Meisenheimer Model

Applied Sciences, 2012
Our simple Meisenheimer model for predicting the principal site for nucleophilic substitution in aromatic perfluorocarbons is further tested on a series of recently published reactions in liquid ammonia primarily from Malykhin and coworkers.
Jon Baker Baker, Max Muir
doaj   +1 more source

New Route to Glycosylated Porphyrins via Aromatic Nucleophilic Substitution (S_NAr)-Synthesis and Cellular Uptake Studies. [PDF]

Int J Mol Sci, 2022
Rosa M, Jędryka N, Skorupska S, Grabowska-Jadach I, Malinowski M.   +4 more
europepmc   +1 more source

Synthesis of Poly(phenylene oxide) Containing Trifluoromethyl Groups via Selective and Sequential Nucleophilic Aromatic Substitution Reaction

, 2016
Synthesis of Poly(phenylene oxide) Containing Trifluoromethyl Groups via Selective and Sequential Nucleophilic Aromatic Substitution ...
Im Sik Chung (1700767), Sang Youl Kim (1700764), Yun Jun Kim (2155135)   +2 more
core   +1 more source

Enantioselective Access to Trifluoromethylated Spirocyclopropyl Heterocycles

Advanced Science, EarlyView.
We report a rhodium‐catalyzed asymmetric [2+1] spirocyclopropanation of methylene azacycles with trifluoromethyl carbenes in situ derived from fluoroalkyl triftosylhydrazones. ABSTRACT Chiral spirocyclopropyl heterocycles have emerged as privileged three‐dimensional structural motifs in medicinal chemistry.
Yuanhao Zhu, Youzhi Xu, Weitao Zhang, Yongyue Ning, Yaojia Jiang, Yongquan Ning, Genping Huang, Jiawei Cheng, Paramasivam Sivaguru, Xihe Bi   +9 more
wiley   +1 more source

Selenophene π‐Core Fusion for Simultaneous Fast Reverse Intersystem Crossing and Narrowband Long‐Wavelength TADF

Angewandte Chemie, EarlyView.
Dibenzo[b,d]selenophene (DBSe) π‐core fusion enables rapid triplet–singlet interconversion while preserving the narrowband emission features of multi‐resonance thermally activated delayed fluorescence (MR‐TADF) luminogens. Combined with peripheral donor engineering, this strategy enables systematic emission tuning from green to red, leading to highly ...
Jingpeng Zhang, Jun Hyeon Lee, Guanting Liu, Tatsuya Mori, Takuma Yasuda   +4 more
wiley   +2 more sources

Palladium-Catalyzed Coupling of Naphthoquinone Triflates with Stannanes. Unprecedented Nucleophilic Aromatic Substitution on a Hydroxynaphthoquinone Triflate

, 2016
Palladium-Catalyzed Coupling of Naphthoquinone Triflates with Stannanes.
Antonio M. Echavarren (1299936), Nuria Tamayo (1854373), Pedro Noheda (3039894), Óscar de Frutos (3039897), Paloma Calle (1925863)   +4 more
core   +1 more source

Scalable Multilayer PTFE‐Reinforced Membranes for Durable, High‐Current‐Density Hydroxide Exchange Membrane Water Electrolysis in Dilute Alkali

Advanced Science, EarlyView.
Low‐Tg HEMs are designed to improve membrane‐electrode adhesion by promoting intimate contact with catalyst layers. After hydration, the membrane develops a hydrogel‐like network that supports water uptake and ion transport while retaining mechanical robustness.
Zhiwei Ren, Yun Zhao, Rui Zhang, Tao Wei, Yingran Zhu, Yangkai Han, Tongzhou Li, Haitao Zhang, Zhigang Shao   +8 more
wiley   +1 more source

Palladium‐Catalyzed Annulations of an Anti‐Bredt Olefin

Angewandte Chemie, EarlyView.
We report metal‐catalyzed trappings of a [2.2.1]‐bridged bicyclic anti‐Bredt olefin (ABO). The methodology yields unusual heterocyclic products and is expected to prompt the further development of unconventional reactions, including metal‐catalyzed processes of ABOs and other strained olefins. ABSTRACT A famous class of alkene‐containing compounds that
Zach G. Walters, Marie Deliaval, Aimee Long, Neil K. Garg   +3 more
wiley   +2 more sources

Tailoring Structure–Property Relationships in π‐Conjugated Heterocyclic Poly(arylene alkylene) Anion‐Exchange Membranes for High‐Performance Water Electrolysis

Advanced Science, EarlyView.
From passive to active ion transport: π‐conjugated heterocycles reconfigure the hydration environment and microphase morphology of p‐terphenyl‐based anion‐exchange membranes, enabling fast hydroxide transport and high‐performance water electrolysis. ABSTRACT Anion‐exchange membrane water electrolysis (AEMWE) is a promising technology for sustainable ...
Qian Wang, Riyang Huang, Wenzhe Zhao, Si Chen, Yunpeng Guo, Yang Wu, Yun Zhao, Patric Jannasch, Jingshuai Yang   +8 more
wiley   +1 more source