Results 51 to 60 of about 12,530 (287)
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Characteristics of lightning‐induced voltages based on experimental data
High Voltage, 2021 This paper presents an analysis of 64 lightning‐induced voltage waveforms recorded in an experimental system implemented in the campus of the University of São Paulo, Brazil.
Michele N. N. Santos, Alexandre Piantini
doaj +1 more source
Studies of in-service and laboratory failures of metal-oxide distribution surge arresters [PDF]
, 2003 We describe the findings from tests and inspections of arresters withdrawn from service, the results of laboratory studies with multipulse lightning currents and high temporary over-voltages, and comparisons of in-service and laboratory failure modes. We
Darveniza, M., Saha, T. K., Wright, S.
core
Survivin and Aurora Kinase A control cell fate decisions during mitosis
Molecular Oncology, EarlyView.Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir +2 more
wiley +1 more source
Development of online monitor for substation 10 kV MOA
The Journal of Engineering, 2019 Metal oxide arresters (MOA) are widely used for over-voltage protection of power facilities in 10 kV distribution networks, and it is hard to determine the failure ones. This study presented an online monitor for 10 kV MOA used in substation.
Xinming Song +4 more
doaj +1 more source
Selection and coordination of surge arresters for switching transient mitigation in photovoltaic power plants [PDF]
, 2017 : Photovoltaic energy generation has become a popular renewable alternative to conventional energy generation that utilise fossil fuels. However, given the diversity and complexity of these PV plants, it is imperative that such plant equipment be ...
Bokoro, P. +3 more
core
Molecular Oncology, EarlyView.CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
Study on the lightning overvoltage protection of a 500 kV unified power flow controller station
The Journal of Engineering, 2018 The unified power flow controller (UPFC) is the third generation of flexible AC transmission systems. It can control the power flow and voltage of the power system quickly and flexibly that has an advantage in compensating the AC transmission system in ...
Ting Ding +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Advances in Electrical and Computer Engineering, 2015 Surge Protective Devices (SPDs) are widely used for protection of the equipment in low-voltage AC power circuits against wide variety of surges. Cascade application of SPDs starting at the service entrance of a building and downstream toward near ...
RADULOVIC, V., MUJOVIC, S., MILJANIC, Z.
doaj +1 more source