Results 71 to 80 of about 438,424 (336)
Translating whole‐genome doubling into precision medicine in cancer
Molecular Oncology, EarlyView.Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
EnergiesAmong various failure causes, lightning overvoltage represents the most significant threat to overhead distribution lines, which serve as critical components in power systems.
Song Zhang +7 more
doaj +1 more source
Study on the lightning overvoltage protection of a 500 kV unified power flow controller station
The Journal of Engineering, 2018 The unified power flow controller (UPFC) is the third generation of flexible AC transmission systems. It can control the power flow and voltage of the power system quickly and flexibly that has an advantage in compensating the AC transmission system in ...
Ting Ding +5 more
doaj +1 more source
Molecular Oncology, EarlyView.This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu +3 more
wiley +1 more source
Advances in Electrical and Computer Engineering, 2015 Surge Protective Devices (SPDs) are widely used for protection of the equipment in low-voltage AC power circuits against wide variety of surges. Cascade application of SPDs starting at the service entrance of a building and downstream toward near ...
RADULOVIC, V., MUJOVIC, S., MILJANIC, Z.
doaj +1 more source
Research on key technologies in ±1100 kV ultra-high voltage DC transmission
High Voltage, 2018 Based on completely mastering ±800 kV transmission technologies, the first ±1100 kV direct current (DC) transmission demonstration project is being constructed in China.
Zehong Liu +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant +11 more
wiley +1 more source
Diagnostics of middle voltage arresters [PDF]
, 2011 W pracy przedstawiono metody oceny stanu technicznego warystorowych ograniczników przepięć średniego napięcia stosowane w badaniach laboratoryjnych oraz w eksploatacji - wykonywane bez wyłączania ograniczników z sieci.
Hasse, L., Olesz, M.
core
Frequency and Time Series Analysis of Surge Arrester in Power Distribution Systems [PDF]
Advances in Engineering and Intelligence SystemsSurge arresters are essential protective devices in power systems that redirect excess voltage and prevent damage to sensitive equipment. Extensive research has been conducted in electro-thermal modeling for surge arresters to better understand and ...
Alireza Zabihi, Mohammad Parhamfar
doaj +1 more source
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source