Results 61 to 70 of about 12,640 (288)
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Development of online monitor for substation 10 kV MOA
The Journal of Engineering, 2019 Metal oxide arresters (MOA) are widely used for over-voltage protection of power facilities in 10 kV distribution networks, and it is hard to determine the failure ones. This study presented an online monitor for 10 kV MOA used in substation.
Xinming Song +4 more
doaj +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Study on the lightning overvoltage protection of a 500 kV unified power flow controller station
The Journal of Engineering, 2018 The unified power flow controller (UPFC) is the third generation of flexible AC transmission systems. It can control the power flow and voltage of the power system quickly and flexibly that has an advantage in compensating the AC transmission system in ...
Ting Ding +5 more
doaj +1 more source
Detonation-flame arrester devices for gasoline cargo vapor recovery systems [PDF]
Empirical data on the deflagration-to-detonation run-up distance for flowing mixtures of gasoline and air in 15.2-cm- (6.0-in.-) diameter piping simulating a vapor recovery system are presented.
Bjorklund, R. A., Ryason, P. R.
core +1 more source
Production improvement in ACM manufacturing company using lean manufacturing approach [PDF]
, 2013 ACM Sdn. Bhd. is a manufacturing company, in which to continuously commit on improvement process which based on the fundamental goal, to minimize or eliminate waste while maximizing production flow.
Sidek, Kamsidi @ Abd Malek
core
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
EnergiesAmong various failure causes, lightning overvoltage represents the most significant threat to overhead distribution lines, which serve as critical components in power systems.
Song Zhang +7 more
doaj +1 more source
Advances in Electrical and Computer Engineering, 2015 Surge Protective Devices (SPDs) are widely used for protection of the equipment in low-voltage AC power circuits against wide variety of surges. Cascade application of SPDs starting at the service entrance of a building and downstream toward near ...
RADULOVIC, V., MUJOVIC, S., MILJANIC, Z.
doaj +1 more source
Research on key technologies in ±1100 kV ultra-high voltage DC transmission
High Voltage, 2018 Based on completely mastering ±800 kV transmission technologies, the first ±1100 kV direct current (DC) transmission demonstration project is being constructed in China.
Zehong Liu +4 more
doaj +1 more source