Results 251 to 260 of about 49,677 (283)

Arrestin Regulation of Small GTPases

2013
The regulation of small GTPases by arrestins is a relatively new way by which arrestin can exert influence over cell signalling cascades, hence, molecular interactions and specific binding partners are still being discovered. A pathway showcasing the regulation of GTPase activity by β-arrestin was first elucidated in 2001.
Ryan T, Cameron, George S, Baillie
openaire   +2 more sources

Quantifying Biased β-Arrestin Signaling

2013
It is now established that agonists do not uniformly activate pleiotropic signaling mechanisms initiated by receptors but rather can bias signals according to the unique receptor conformations they stabilize. One of the important emerging signaling systems where this can occur is through β-arrestin.
openaire   +2 more sources

Arrestins

2022
openaire   +1 more source

Splice Variants of Arrestins

Experimental Eye Research, 1996
K, Palczewski, W C, Smith
openaire   +2 more sources

Arrestins

2013
Cornelia Walther, Stephen S.G. Ferguson
openaire   +1 more source

Arrestin Pathways as Drug Targets

2013
Our growing appreciation of the pluridimensionality of G protein-coupled receptor (GPCR) efficacy, coupled with the phenomenon of orthosteric ligand "bias," offers the prospect of drugs that selectively modulate different aspects of GPCR function for therapeutic benefit.
openaire   +2 more sources

Tail engagement of arrestin at the glucagon receptor

Nature, 2023
, Qiang Zhao, Beili Wu
exaly  

Arrestins

2006
openaire   +2 more sources

Structure of the neurotensin receptor 1 in complex with β-arrestin 1

Nature, 2020
Weijiao Huang, Matthieu Masureel, Qianhui Qu   +2 more
exaly  

True Arrestins and Arrestin-Fold Proteins

2013
Laurence Aubry, Gérard Klein
openaire   +1 more source