Results 31 to 40 of about 1,528,347 (359)

Clinical overview on RASopathies

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, Volume 190, Issue 4, Page 414-424, December 2022., 2022
Abstract RASopathies comprise a group of clinically overlapping developmental disorders caused by genetic variations affecting components or modulators of the RAS‐MAPK signaling cascade, which lead to dysregulation of signal flow through this pathway.
Martin Zenker
wiley   +1 more source

Cardiac Arrhythmias in Autoimmune Diseases.

Circulation Journal, 2020
Autoimmune diseases (ADs) affect approximately 10% of the world's population. Because ADs are frequently systemic disorders, cardiac involvement is common.
M. Gawałko, P. Balsam, P. Lodziński, M. Grabowski, B. Krzowski, G. Opolski, J. Kosiuk   +6 more
semanticscholar   +1 more source

Advanced ablation strategies for management of post-surgical atrial arrhythmias. [PDF]

, 2013
Post-surgical arrhythmias include a wide range of arrhythmias occurring late after cardiac surgery and represent a complex substrate for catheter ablation either because of extended scar and remodeling or because of limited access to the area of interest.
Babu-Narayan, SV, Ernst, S, Mantziari, L, Suman-Horduna, I   +3 more
core   +1 more source

Mechanisms of cardiac arrhythmias [PDF]

Journal of Arrhythmia, 2015
AbstractBlood circulation is the result of the beating of the heart, which provides the mechanical force to pump oxygenated blood to, and deoxygenated blood away from, the peripheral tissues. This depends critically on the preceding electrical activation.
openaire   +6 more sources

A study of early afterdepolarizations in a model for human ventricular tissue [PDF]

, 2014
Sudden cardiac death is often caused by cardiac arrhythmias. Recently, special attention has been given to a certain arrhythmogenic condition, the long-QT syndrome, which occurs as a result of genetic mutations or drug toxicity. The underlying mechanisms
Kazbanov, Ivan, Nuitermans, Anita, Pandit, Rahul, Panfilov, Alexander, Vandersickel, Nele, Weise, Louis   +5 more
core   +3 more sources

Cardiac Genetic Investigation of Sudden Infant and Early Childhood Death: A Study From Victims to Families

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2023
Background Sudden infant death syndrome (SIDS) is the leading cause of death up to age 1. Sudden unexplained death in childhood (SUDC) is similar but affects mostly toddlers aged 1 to 4.
Maria‐Christina Kotta, Margherita Torchio, Pauline Bayliss, Marta C. Cohen, Oliver Quarrell, Nigel Wheeldon, Tamás Marton, Davide Gentilini, Lia Crotti, Robert C. Coombs, Peter J. Schwartz   +10 more
doaj   +1 more source

Ventricular Arrhythmias in Cardiac Amyloidosis: A Review of Current Literature

Clinical Medicine Insights: Cardiology, 2020
Cardiac Amyloidosis is an infiltrative cardiomyopathy which occurs secondary to deposition of mis-folded protein in the myocardium, with the two most common subtypes being AL amyloidosis and TTR amyloidosis.
S. Khanna, P. Lo, Kenneth K Cho, R. Subbiah   +3 more
semanticscholar   +1 more source

Successful catheter cryoablation for premature ventricular contractions originating from the para‐Hisian region

Clinical Case Reports, 2019
We achieved successful catheter cryoablation in a patient with para‐Hisian premature ventricular contractions (PVCs) without conduction disturbance using the freeze‐thaw‐freeze method while observing the atrial‐His bundle interval.
George Suzuki, Akihiko Yotsukura, Tadafumi Nanbu, Masayuki Sakurai   +3 more
doaj   +1 more source

Use of hiPSC-Derived Cardiomyocytes to Rule Out Proarrhythmic Effects of Drugs: The Case of Hydroxychloroquine in COVID-19

Frontiers in Physiology, 2022
In the early phases of the COVID-19 pandemic, drug repurposing was widely used to identify compounds that could improve the prognosis of symptomatic patients infected by SARS-CoV-2.
Luca Sala, Vladislav Leonov, Vladislav Leonov, Manuela Mura, Federica Giannetti, Aleksandr Khudiakov, Alessandra Moretti, Alessandra Moretti, Lia Crotti, Lia Crotti, Lia Crotti, Massimiliano Gnecchi, Massimiliano Gnecchi, Peter J. Schwartz   +13 more
doaj   +1 more source

Initiation and dynamics of a spiral wave around an ionic heterogeneity in a model for human cardiac tissue [PDF]

, 2013
In relation to cardiac arrhythmias, heterogeneity of cardiac tissue is one of the most important factors underlying the onset of spiral waves and determining their type.
Dawyndt, Peter, Defauw, Arne, Panfilov, Alexander   +2 more
core   +2 more sources