Results 101 to 110 of about 8,884 (302)

Total arsenic and arsenic species in selected seafoods: Analysis using high-performance liquid chromatography- inductively coupled plasma mass spectrometry and health risk assessment

Journal of Chromatography Open
The objective of the present study was to determine the inorganic and organic arsenic species and assess the actual risk of selected seafood produced in Sri Lanka in terms of inorganic arsenic species. A total of 80 samples, comprising 75 seafood samples
J.A.K.S. Jayakody, E.M.R.K.B. Edirisinghe, S.A. Senevirathne, L. Senarathna   +3 more
doaj   +1 more source

Arzén, szelén és rokon félfémek kiválasztása az epével - kölcsönhatásuk a glutationnal és egymással [PDF]

, 1999
4
Gyurasics Ágnes
core  

Geochemical and Geological Investigation of Skarn‐Type Pb–Zn Mineralization in Hastanetepe (Balya‐Balıkesir, Türkiye): An Approach Based on Fluid Inclusions, Sulphur Isotopes and Geochemical Data

Geological Journal, EarlyView.
Integrated petrographic, mineralogical and geochemical data from the Hastanetepe Pb–Zn deposit (Balya, Türkiye) reveal multi‐stage hydrothermal alteration and a magmatic sulphur source. Fluid inclusion and sulphur isotope results indicate a complex fluid evolution responsible for skarn‐type Pb–Zn mineralization along limestone–dacite contacts ...
Esra Ünal‐Çakır
wiley   +1 more source

Genomic Analysis of Stress Response Against Arsenic in \u3cem\u3eCaenorhabditis elegans\u3c/em\u3e [PDF]

, 2013
Arsenic, a known human carcinogen, is widely distributed around the world and found in particularly high concentrations in certain regions including Southwestern US, Eastern Europe, India, China, Taiwan and Mexico.
Bozdag, Serdar, Cinar, Hediye Nese, Lee, Jeong H., Lewis, Jada, Patel, Isha, Sahu, Surasri N., Sprando, Robert   +6 more
core   +1 more source

Trypanosomatid Aquaporins: Roles in Physiology and Drug Response [PDF]

, 2013
In the class Kinetoplastida, we find an order of parasitic protozoans classified as Trypanosomatids. Three major pathogens form part of this order, Trypanosoma cruzi, Trypanosoma brucei, and Leishmania, which are responsible for disease and fatalities in
Mandal, Goutam, Mukhopadhyay, Rita, Orta, Jose F., Sharma, Mansi   +3 more
core   +1 more source

Systemic anti‐cancer therapy associated with the occurrence of peripheral neurotoxicity and, specifically, peripheral neuropathy

International Journal of Cancer, EarlyView.
What's New? While the effectiveness of systemic anticancer therapy is well documented, it commonly causes severe toxicity. This study of the 467 systemic anticancer therapy agents currently approved globally for clinical and/or research purposes found that peripheral neurotoxicity is associated with 45% of classical chemotherapies, 21% of targeted ...
Cassie Higgins, Lynn R. Gauthier, Blair H. Smith, Lesley Colvin   +3 more
wiley   +1 more source

SUMOylation regulates tumorigenesis and progression: Molecular mechanisms and therapeutic applications

Interdisciplinary Medicine, EarlyView.
SUMOylation, a dynamic post‐translational modification, acts as a master regulator at the heart of tumor malignancy. Our work delineates how the SUMOylation cycle—mediated by E1/E2/E3 enzymes and reversed by SENPs—orchestrates multiple hallmarks of cancer. The central pathway converges on three critical pathological axes: 1.
Yimao Wu, Zichang Chen, Yinting Hu, Gokhan Zengin, Qian Zhang, Meng‐Yao Li, Wenlong Sun   +6 more
wiley   +1 more source

Macrophage extracellular vesicles deliver Mef2d proteins to aggravate Bacteroides fragilis pathogenicity in type 2 diabetes arterial calcification

Interdisciplinary Medicine, EarlyView.
Bacteroides fragilis is associated with type 2 diabetes (T2D) arterial calcification and can be activated by macrophage‐derived extracellular vesicles (EVs). BF takes up EVs via receptor‐mediated endocytosis, and activation is induced by EV‐derived Mef2d, thereby inhibiting ArsR family transcriptional regulator transcription.
Cong Chen, Rong He, Jirong Luo, Zhengfeng Liang, Qunwen Pan, Shuangquan Liu, Jingsong Cao   +6 more
wiley   +1 more source

Insights into antitrypanosomal drug mode-of-action from cytology-based profiling.

PLoS Neglected Tropical Diseases, 2018
Chemotherapy continues to have a major impact on reducing the burden of disease caused by trypanosomatids. Unfortunately though, the mode-of-action (MoA) of antitrypanosomal drugs typically remains unclear or only partially characterised.
James A Thomas, Nicola Baker, Sebastian Hutchinson, Caia Dominicus, Anna Trenaman, Lucy Glover, Sam Alsford, David Horn   +7 more
doaj   +1 more source

Paternal Exposure to the Neonicotinoid Pesticide Clothianidin Alters Sperm MicroRNA Profiles in Mice and Intergenerationally Reduces Locomotor Activity in Male Offspring

Journal of Applied Toxicology, EarlyView.
ABSTRACT Accumulating evidence suggests that paternal environmental factors have epigenetic effects on sperm and influence offspring. Neonicotinoid pesticides (NNs), which are widely used around the world, are known to affect offspring phenotypes through maternal exposure in mice, but the effect of the paternal exposure remains unknown.
Makiko Ito, Tetsushi Hirano, Sarika Nunobiki, Ayano Yoshimoto, Yukako Hara, Yuya Ishida, Sakura Yonoichi, Youhei Mantani, Toshifumi Yokoyama, Yoshiaki Tabuchi, Yoshinori Ikenaka, Nobuhiko Hoshi   +11 more
wiley   +1 more source