Results 11 to 20 of about 8,884 (302)

Mitochondrial ROS, ER Stress, and Nrf2 Crosstalk in the Regulation of Mitochondrial Apoptosis Induced by Arsenite

open access: yesAntioxidants, 2022
Long-term ingestion of arsenicals, a heterogeneous group of toxic compounds, has been associated with a wide spectrum of human pathologies, which include various malignancies.
Orazio Cantoni   +4 more
doaj   +1 more source

Gut microbiota metabolize arsenolipids in a donor dependent way

open access: yesEcotoxicology and Environmental Safety, 2022
Understanding the interplay between the gut microbiome and arsenolipids can help us manage the potential health risk of consuming seafood, but little is known about the bioconversion fate of arsenolipids in the gastrointestinal tract.
Chan Xiong   +3 more
doaj   +1 more source

Exposure to arsenic and level of Vitamin D influence the number of Th17 cells and production of IL-17A in human peripheral blood mononuclear cells in adults

open access: yesPLoS ONE, 2022
There is limited evidence on the effects of environmental exposure to arsenic (As) on the immune system in adults. In a population-based study, we have found that urinary As (UAs), and its metabolites [inorganic As (InAs), monomethylated arsenicals (MMA ...
Faruque Parvez   +10 more
doaj   +3 more sources

Arsenic Metabolism, Toxicity and Accumulation in the White Button Mushroom Agaricus bisporus

open access: yesToxics, 2022
Mushrooms have unique properties in arsenic metabolism. In many commercial and wild-grown mushrooms, arsenobetaine (AsB), a non-toxic arsenical, was found as the dominant arsenic species.
Owen Dong   +3 more
doaj   +1 more source

Germination and early seedling development of Helichrysum microphyllum Cambess. subsp. tyrrhenicum Bacch., Brullo & Giusso in the presence of arsenates and arsenites

open access: yesHeliyon, 2022
Arsenate, As(V), and arsenite, As(III), are the most available arsenicals present in the soil solutions, in particular in mine polluted substrates, and cause several symptoms of toxicity in plants (like inhibition of seed germination and reduction of ...
Maria Enrica Boi   +6 more
doaj   +1 more source

Arsenic: A Review on a Great Health Issue Worldwide

open access: yesApplied Sciences, 2022
Arsenic intoxication represents a worldwide health problem and occurs mainly through drinking water. Arsenic, a metalloid and naturally occurring element, is one of the most abundant elements in the earth’s crust, whose toxicity depends on the reduction ...
Giuseppe Genchi   +4 more
doaj   +1 more source

Pathway of human AS3MT arsenic methylation [PDF]

open access: yes, 2014
A synthetic gene encoding human As(III) S-adenosylmethionine (SAM) methyltransferase (hAS3MT) was expressed, and the purified enzyme was characterized.
Dheeman, Dharmendra S.   +3 more
core   +2 more sources

Arsenic

open access: yesCA: A Cancer Journal for Clinicians, 2001
The toxicity and carcinogenicity of arsenic are well known, but vexing questions remain. The current controversy over the appropriate Federal limit for arsenic in drinking water highlights some of the difficult scientific, ethical, economic, and political issues that complicate standard-setting in occupational and environmental health.
H, Frumkin, M J, Thun
openaire   +2 more sources

Transcriptional circuitry atlas of genetic diverse unstimulated murine and human macrophages define disparity in population-wide innate immunity

open access: yesScientific Reports, 2021
Macrophages are ubiquitous custodians of tissues, which play decisive role in maintaining cellular homeostasis through regulatory immune responses. Within tissues, macrophage exhibit extremely heterogeneous population with varying functions orchestrated ...
Bharat Mishra   +2 more
doaj   +1 more source

Trypanosoma brucei aquaglyceroporin 2 is a high-affinity transporter for pentamidine and melaminophenyl arsenic drugs and the main genetic determinant of resistance to these drugs. [PDF]

open access: yes, 2013
OBJECTIVES: Trypanosoma brucei drug transporters include the TbAT1/P2 aminopurine transporter and the high-affinity pentamidine transporter (HAPT1), but the genetic identity of HAPT1 is unknown. We recently reported that loss of T.
Aguinaga Andrés, David   +19 more
core   +4 more sources

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