Results 91 to 100 of about 12,135 (165)

Efficacy of artemether-lumefantrine for the treatment of uncomplicated Plasmodium falciparum malaria in Northeast Ethiopia [PDF]

, 2017
Background: The impact of resistance to antimalarials is insidious and unless efficacy studies are conducted, resistance may go unrecognized. The aim of this study was to assess the efficacy of artemether/lumefantrine, for the treatment of uncomplicated ...
Mulu, Assefa, Geresu, Berhanu, Ademe, Muluneh, Beyene, Yeshiwork   +3 more
core   +1 more source

Artemether/Lumefantrine for the Treatment of P. malariae in a Patient on Hemodialysis

Case Reports in Medicine, 2019
The combination of artemether/lumefantrine is indicated for the treatment of acute uncomplicated Plasmodium falciparum malaria. There have been no clinical trials to assess the efficacy of this medication in patients with renal impairment.
Rita Patrocínio-Jesus, João Cunha, Diva Trigo, Bárbara Flor-de-Lima, Patrícia Pacheco   +4 more
doaj   +1 more source

Development of the RP-HPLC Method for Simultaneous Determination and Quantification of Artemether and Lumefantrine in Fixed-Dose Combination Pharmaceutical Dosage Forms

Advances in Pharmacological and Pharmaceutical Sciences
Developing countries face enormous challenges with substandard and falsified antimalarial drugs. One specific issue is the lack of a simple, cost-effective, and robust HPLC method to simultaneously determine and quantify the active pharmaceutical ...
Simon Nyarko, Kwabena Ofori-Kwakye, Raphael Johnson, Noble Kuntworbe, Desmond Asamoah Bruce Otu, Denis Dekugmen Yar, Yaa Asantewaa Osei   +6 more
doaj   +1 more source

Ototoxicity of artemether/lumefantrine in the treatment of falciparum malaria: a randomized trial

Malaria Journal, 2008
Background Due to increasing drug resistance, artemisinin-based combination chemotherapy (ACT) has become the first-line treatment of falciparum malaria in many endemic countries. However, irreversible ototoxicity associated with artemether/lumefantrine (
Krause Eike, Girma Tsinuel, Mamo Yoseph, Berens-Riha Nicole, Miranda Isabel, Eshetu Teferi, Gürkov Robert, Schmidt Michael, Hempel John-Martin, Löscher Thomas   +9 more
doaj   +1 more source

Artemether-lumefentrine vs quinine in cerebral malaria.pdf

, 2016
Quinine by exploring its effectiveness in cerebral malaria in hospitalized patients. Materials and Methods: A randomized prospective study was conducted among 64 hospitalized cases of cerebral malaria.
AHMED TANJIMUL ISLAM (Tanjim Ovee) (3234204)
core   +1 more source

Assessment of the therapeutic efficacy of artemether-lumefantrine in the treatment of uncomplicated Plasmodium falciparum malaria in northern KwaZulu-Natal: an observational cohort study

Malaria Journal, 2012
Background Recent malaria epidemics in KwaZulu-Natal indicate that effective anti-malarial therapy is essential for malaria control. Although artemether-lumefantrine has been used as first-line treatment for uncomplicated Plasmodium falciparum malaria in
Vaughan-Williams Charles H, Raman Jaishree, Raswiswi Eric, Immelman Etienne, Reichel Holger, Gate Kelly, Knight Steve   +6 more
doaj   +1 more source

Interaction between artemether-lumefantrine and nevirapine-based antiretroviral therapy in HIV-1-infected patients.

, 2011
Artemether-lumefantrine and nevirapine-based antiretroviral therapy (ART) are the most commonly recommended first-line treatments for malaria and HIV, respectively, in Africa.
Barnes, KI, Maartens, G., Kredo, T., Smith, P., Van der Walt, JS, Barnes, K. I., Cohen, K, Smith, P, T. Kredo, Wiesner, L., L. Wiesner, G. Maartens, Cohen, K., van der Walt, Jan-Stefan,, K. Mauff, K. I. Barnes, Mauff, K., Maartens, G, Kredo, T, J. S. Van der Walt, Mauff, K, P. Smith, Wiesner, L, K. Cohen   +23 more
core   +1 more source

Forest plot for artemether-lumefantrine PCR adjusted cure rate based on the per protocol analysis.

, 2022
Forest plot for artemether-lumefantrine PCR adjusted cure rate based on the per protocol analysis.
Anthony Kapesa (5560253), Jackson Mukonzo (8433558), Gote Swedberg (72692), Vito Baraka (829689), Erasmus Kamugisha (4744887), Karol Marwa (4744893), Evelyne Konje (12225517), Benson Kidenya (3491327)   +7 more
core   +1 more source

Artemisinin-naphthoquine versus artemether-lumefantrine for uncomplicated malaria in Papua New Guinean children: an open-label randomized trial.

PLoS Medicine, 2014
BackgroundArtemisinin combination therapies (ACTs) with broad efficacy are needed where multiple Plasmodium species are transmitted, especially in children, who bear the brunt of infection in endemic areas.
Moses Laman, Brioni R Moore, John M Benjamin, Gumul Yadi, Cathy Bona, Jonathan Warrel, Johanna H Kattenberg, Tamarah Koleala, Laurens Manning, Bernadine Kasian, Leanne J Robinson, Naomi Sambale, Lina Lorry, Stephan Karl, Wendy A Davis, Anna Rosanas-Urgell, Ivo Mueller, Peter M Siba, Inoni Betuela, Timothy M E Davis   +19 more
doaj   +1 more source

The pharmacokinetics of artemether and lumefantrine in pregnant women with uncomplicated falciparum malaria.

, 2016
OBJECTIVE: To determine the pharmacokinetic properties of artemether and lumefantrine (AL) in pregnant women with recrudescent uncomplicated multi-drug resistant falciparum malaria.

core   +1 more source