Malaria polymerase chain reaction (PCR) testing is more sensitive than conventional diagnostics. Routine PCR screening of at‐risk asymptomatic hematopoietic cell donors and transplant candidates may prevent unnecessary deferrals or treatment. In our experience, PCR negativity during screening or after treatment supports donor/candidate eligibility ...
Mary M. Czech +5 more
wiley +1 more source
Background In Guyana, chloroquine + primaquine is used for the treatment of vivax malaria. A worldwide increase of chloroquine resistance in Plasmodium vivax led to questioning of the current malaria treatment guidelines. A therapeutic efficacy study was
Eibach Daniel +6 more
doaj +1 more source
Molecular Markers of Antimalarial Drug Resistance in Plasmodium falciparum From Kumasi, Ghana, 2023
ABSTRACT Objectives Artemisinin partial resistance has emerged in East Africa and is feared to spread across the continent, potentially compromising artemisinin‐based combination treatment. Molecular markers can serve as early warning signals for the development of specific drug resistance.
Albert Dennis Kegya +10 more
wiley +1 more source
Artemether-Lumefantrine Treatment Failure despite adequate lumefantrine day 7 Concentration in a Traveller with Plasmodium Falciparum Malaria after Returning from Tanzania. [PDF]
Artemether-lumefantrine is currently first-line therapy of Plasmodium falciparum malaria in many countries. This report describes a treatment failure despite adequate drug concentrations in a traveller returning from sub-Saharan Africa.
Färnert, Anna +6 more
core
Severe Plasmodium knowlesi Malaria in a Tertiary Care Hospital, Sabah, Malaysia
The simian parasite Plasmodium knowlesi causes severe human malaria; the optimal treatment remains unknown. We describe the clinical features, disease spectrum, and response to antimalarial chemotherapy, including artemether-lumefantrine and artesunate ...
Timothy William +10 more
doaj +1 more source
Tablet Manipulation Practices Among Community Pharmacy Clients in Ghana: A Cross‐Sectional Survey
Background Tablets are preferred dosage forms due to their accurate dosing, stability, and easy handling and administration. Oral tablets are sometimes manipulated via splitting or crushing before intake for dose flexibility and other reasons to meet specific needs.
Hilda Amekyeh +11 more
wiley +1 more source
Safety and tolerability of combination antimalarial therapies for uncomplicated falciparum malaria in Ugandan children. [PDF]
BACKGROUND: Combination antimalarial therapy is recommended for the treatment of uncomplicated falciparum malaria in Africa; however, some concerns about the safety and tolerability of new regimens remain.
Njama-Meya Denise +32 more
core +1 more source
Artemether/Lumefantrine for the Treatment of P. malariae in a Patient on Hemodialysis
The combination of artemether/lumefantrine is indicated for the treatment of acute uncomplicated Plasmodium falciparum malaria. There have been no clinical trials to assess the efficacy of this medication in patients with renal impairment.
Rita Patrocínio-Jesus +4 more
doaj +1 more source
Progression of Malaria in the Human Body, Its Effects on the Liver and Its Various Aspects
Malaria, an infectious disease caused by Plasmodium parasites, is a significant global health issue, particularly in tropical and subtropical regions. Understanding the development of malaria in the human body and its effects on vital organs like the liver is crucial for effective control and prevention.
Avishek Mandal +7 more
wiley +1 more source
Pharmaco-epidemiology of artemisinin-based combination therapy in the context of impact evaluation of artemether-lumefantrine on malaria morbidity and mortality during programmatic implementation in rural Tanzania [PDF]
In sub-Saharan Africa previous efforts to control malaria have proved less successful mostly due to prolonged use of less efficacious mono-therapy drugs to which Plasmodium falciparum has developed drug resistance.
Kabanywanyi, Abdunoor Mulokozi
core +1 more source

