Results 121 to 130 of about 8,416 (212)
This study evaluated the gastroprotective potential of Pomegranate peel extract compared to Omeprazole. The extract demonstrated significant in vitro anti‐H. pylori and anti‐inflammatory activities. In vivo experiments on indomethacin‐induced rats revealed that the extract effectively reduced gastric acidity and ulcer indices while restoring gastric ...
Talat M. Hashem +4 more
wiley +1 more source
Artemisone effective against murine cerebral malaria
Background Artemisinins are the newest class of drug approved for malaria treatment. Due to their unique mechanism of action, rapid effect on Plasmodium, and high efficacy in vivo, artemisinins have become essential components of malaria treatment ...
Waknine-Grinberg Judith H +8 more
doaj +1 more source
ABSTRACT Tumour immunotherapy targeting PD‐1/PD‐L1 shows promise, but the regulatory mechanisms of PD‐L1 and its small‐molecule modulators remain unclear. This study investigated FoxO3a‐mediated PD‐L1 regulation and the PD‐L1‐inhibitory role of dihydroartemisinin (DA) in triple‐negative breast cancer (TNBC).
Xingan Xing +8 more
wiley +1 more source
Background Anti-malarial drug resistance has emerged as one of the biggest challenges confronting the worldwide effort to control malaria. The appearance of chloroquine and multi-drug resistance had devastating effects on therapeutic efficacy of former ...
Brasil Larissa W +8 more
doaj +1 more source
ABSTRACT Soybean growth and yield are susceptible to abiotic stresses such as phosphate (P) deficiency and drought. Symbiotic association of plant roots with arbuscular mycorrhizal fungi (AMF) can improve water uptake, thereby increasing stress resilience.
Muhammad Adeel Hassan +3 more
wiley +1 more source
Cannabis‐Derived Compounds Against Plasmodium sp.: A Systematic Review of Preclinical Studies
ABSTRACT Objective This study aims to evaluate preclinical studies on the effects and toxicity of cannabis‐derived compounds against Plasmodium sp. Methods A literature search was conducted in Web of Science, PubMed, Scopus and LILACS databases until December 2024. Studies that assessed the activity or toxicity of cannabis against Plasmodium sp.
Tácio de Mendonça Lima +5 more
wiley +1 more source
Artemisinin: large community studies
Prospective randomized trials with oral artemisinin derivatives have been conducted in over 1000 patients to determine the optimum treatment of multi-drug resistant falciparum malaria on the Thai-Burmese border. These drugs have proved valuable in 3 settings.
openaire +2 more sources
Coccidiosis is one of the most common diseases in the poultry industry worldwide (especially in broilers aged 3–6 weeks), causing significant economic losses to poultry farmers and governments every year. Conventional methods (anticoccidial chemical compounds) for the coccidiosis debarment and control always present challenges and disadvantages, such ...
Fatemeh Aziz-Aliabadi +3 more
wiley +1 more source
Background The leaves of Dimocarpus longan Lour. are used unilaterally as Chinese herbal medicines to treat diabetes in Chongzuo and Hezhou, Guangxi, but the mechanism of its treatment of diabetes is not yet clear, and further research is needed. Methods This study examined the effects of leaf ethanol extract of D.s longan Lour.
Chunlian Lu +13 more
wiley +1 more source
In vitro and in vivo activity of 3-alkoxy-1,2-dioxolanes against Schistosoma mansoni [PDF]
Objectives Compounds characterized by a peroxidic skeleton are an interesting starting point for antischistosomal drug discovery. Previously a series of 3-alkoxy-1,2-dioxolanes, which are chemically stable cyclic peroxides, demonstrated significant in ...
Benner, Evan +5 more
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