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Akupunktur & Aurikulomedizin, 2016
Der Pflanzeninhaltsstoff Artemisinin des Einjahrigen Beifus (Artemisia annua) ist durch die Verleihung des Medizinnobelpreises an die chinesische Forscherin Tu Youyou in den Fokus der Offentlichkeit geruckt. Die medizinische Verwendung der Pflanze weist eine lange Tradition auf.
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Der Pflanzeninhaltsstoff Artemisinin des Einjahrigen Beifus (Artemisia annua) ist durch die Verleihung des Medizinnobelpreises an die chinesische Forscherin Tu Youyou in den Fokus der Offentlichkeit geruckt. Die medizinische Verwendung der Pflanze weist eine lange Tradition auf.
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Artemisinins: Artemisinin, Dihydroartemisinin, Artemether and Artesunate
2011Artemisinin comes from the plant, Artemisia annua, an ancient Chinese herbal remedy for relapsing fever. Rediscovery of its antimalarial action in China in the 1970s has seen it and its semisynthetic derivatives become the most useful drugs for most malarial illness. Artemisinins have a sesquiterpene lactone structure.
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Artemisinins and immune system
European Journal of Pharmacology, 2011Artemisinins in combination with other antimalarial drugs remain the mainstay of current antimalarial armamentarium. It is interesting to note that many traditional drugs with antiprotozoal background can wield immunomodulation on the recipient's immune system in a positive or negative direction. Artemisinins also attribute immunomodulatory distensions.
Lubna, Shakir +4 more
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An Update on Artemisinin Resistance
2019While the precise mode of action of artemisinin (ART) derivatives remains obscure, it is nonetheless commonly accepted that ART generates reactive oxygen intermediates that contribute to cell death. Also, numerous studies confirm that point mutations in the propeller domain of K13 protein play a key role in resistance to ART derivatives. Because of its
Ariey, Frederic, Ménard, Didier
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Unpacking ‘Artemisinin Resistance’
Trends in Pharmacological Sciences, 2017Artemisinin and its derivatives, in combination with partner drugs, are currently the most effective treatments for malaria parasite infection. Even though artemisinin has been widely used for decades, its mechanism of action had remained controversial until recently.
Jigang, Wang +3 more
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A Concise Synthesis of (+)-Artemisinin
Journal of the American Chemical Society, 2012Malaria represents one of the most medically and economically debilitating diseases present in the world today. Fortunately, there exists a highly effective treatment based on the natural product artemisinin. Despite the development of several synthetic approaches to the natural product, a streamlined synthesis that utilizes low-cost chemical inputs ...
Chunyin, Zhu, Silas P, Cook
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The Controversy About the Effects of Artemisinins on Pancreatic α Cell Reprogramming and Diabetes
Trends in Endocrinology and Metabolism, 2023Jin Li
exaly
Antimalarial and Anticancer Properties of Artesunate and Other Artemisinins: Current Development
Monatshefte Für Chemie, 2021Pitambar Khanal
exaly