Results 1 to 10 of about 54,307 (263)

Rat models for arterial calcification associated with chronic kidney disease: a systematic review and meta-analysis [PDF]

BMC Cardiovascular Disorders
Arterial calcification represents a major burden in chronic kidney disease (CKD) and is an independent risk factor for cardiovascular diseases (CVD). Rodent models are essential for preclinical research on arterial calcification mechanisms and potential ...
Nicolas Hense, Melina Stein, Nikolaus Marx, Nadine Kaesler, Claudia Goettsch   +4 more
doaj   +2 more sources

Arterial calcification due to CD73 deficiency presenting with critical limb-threatening ischemia successfully treated with iliac endarterectomy and distal bypass [PDF]

Journal of Vascular Surgery Cases and Innovative Techniques
Arterial calcification due to CD73 deficiency is a rare disorder causing progressive medial calcification. Revascularization reports remain scarce. We describe a 67-year-old woman with arterial calcification due to CD73 deficiency and critical limb ...
Yusuke Kato, MD, Etsuko Hisanaga, MD, PhD, Takuya Koyano, MD, Naoki Konno, MD, Hayato Ikota, MD, PhD, Wataru Tatsuishi, MD, PhD   +5 more
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Future treatments for the arteriopathy of ectopic calcification disorders

Frontiers in Drug Discovery, 2023
Ectopic calcification disorders, including Generalized Arterial Calcification of Infancy (GACI) and Pseudoxanthoma Elasticum are rare but impactful on individuals, healthcare and society, with significant associated morbidity, mortality and healthcare ...
Benjamin M. Davies, Frank Rutsch, Naren Vyavahare, Naren Vyavahare, Alexander Jones, Alexander Jones, Alexander Jones   +6 more
doaj   +1 more source

The Cell Origin and Role of Osteoclastogenesis and Osteoblastogenesis in Vascular Calcification

Frontiers in Cardiovascular Medicine, 2021
Arterial calcification refers to the abnormal deposition of calcium salts in the arterial wall, which results in vessel lumen stenosis and vascular remodeling.
Wenhong Jiang, Zhanman Zhang, Yaodong Li, Chuanzhen Chen, Han Yang, Qiuning Lin, Ming Hu, Xiao Qin   +7 more
doaj   +1 more source

Antihypertensive treatment with hydrochlorothiazide-hydralazine combination aggravates medial vascular calcification in CKD rats with mineral bone disorder

Frontiers in Cardiovascular Medicine, 2023
BackgroundArterial stiffness and medial vascular calcification, leading to isolated systolic blood pressure (BP), are major cardiovascular risk factors in patients with chronic kidney disease (CKD) and mineral bone disorders (MBD).
Richard Larivière, Richard Larivière, Roth-Visal Ung, Sylvain Picard, Darren E. Richard, Darren E. Richard, Fabrice Mac-Way, Fabrice Mac-Way, Mohsen Agharazii, Mohsen Agharazii   +9 more
doaj   +1 more source

Regional distribution and severity of arterial calcification in patients with chronic kidney disease stages 1–5: a cross-sectional study of the Copenhagen chronic kidney disease cohort

BMC Nephrology, 2020
Background Patients with chronic kidney disease (CKD) and arterial calcification are considered at increased risk of adverse cardiovascular outcomes. However, the optimal site for measurement of arterial calcification has not been determined. The primary
Ida Maria Hjelm Sørensen, Sasha Asbøll Kepler Saurbrey, Henrik Øder Hjortkjær, Philip Brainin, Nicholas Carlson, Ellen Linnea Freese Ballegaard, Anne-Lise Kamper, Christina Christoffersen, Bo Feldt-Rasmussen, Klaus Fuglsang Kofoed, Susanne Bro   +10 more
doaj   +1 more source

Lower Levels of Osteoprotegerin in Subjects with Arterial Calcification and an Inverse Correlation Between Osteoprotegerin and Lipoprotein (a) Levels

Endocrinology Research and Practice, 2022
Osteoporosis an d vascular disease are common and important causes of morbidity and mortality in elderly people. We aimed to evaluate serum osteoprotegerin (OPG) levels and their correlation with radial artery calcification and lipid profile in 36 ...
Adnan Gökçel, H. Tarık Kızıltan, Fazilet Kayaselçuk, Mehmet Baltalı, Nilgün Güvener Demirağ, Fatih Yalçın   +5 more
doaj   +2 more sources

Endogenous Calcification Inhibitors in the Prevention of Vascular Calcification: A Consensus Statement From the COST Action EuroSoftCalcNet

Frontiers in Cardiovascular Medicine, 2019
The physicochemical deposition of calcium-phosphate in the arterial wall is prevented by calcification inhibitors. Studies in cohorts of patients with rare genetic diseases have shed light on the consequences of loss-of-function mutations for different ...
Magnus Bäck, Tamas Aranyi, M. Leonor Cancela, Miguel Carracedo, Natércia Conceição, Georges Leftheriotis, Vicky Macrae, Ludovic Martin, Yvonne Nitschke, Andreas Pasch, Daniela Quaglino, Frank Rutsch, Catherine Shanahan, Victor Sorribas, Flora Szeri, Flora Szeri, Pedro Valdivielso, Olivier Vanakker, Hervé Kempf   +18 more
doaj   +1 more source

Kidney Function and Arterial Calcification in Major Vascular Beds

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2019
Background The purpose of this study was to investigate the association between kidney function and arterial calcification in major vascular beds and to establish whether arterial calcification mediates the relation between kidney function measures and ...
Sanaz Sedaghat, Ewout J. Hoorn, M. Arfan Ikram, Carolien Koop‐Nieuwelink, Maryam Kavousi, Oscar H. Franco, Aad van der Lugt, Meike W. Vernooij, Daniel Bos   +8 more
doaj   +1 more source

The crosstalk between endothelial cells and vascular smooth muscle cells aggravates high phosphorus-induced arterial calcification

Cell Death and Disease, 2022
Arterial calcification is highly prevalent, particularly in patients with end-stage renal disease (ESRD). The osteogenic differentiation of vascular smooth muscle cells (VSMCs) is the critical process for the development of arterial calcification ...
Xiao Lin, Su-Kang Shan, Feng Xu, Jia-Yu Zhong, Feng Wu, Jia-Yue Duan, Bei Guo, Fu-Xing-Zi Li, Yi Wang, Ming-Hui Zheng, Qiu-Shuang Xu, Li-Min Lei, Wen-Lu Ou-Yang, Yun-Yun Wu, Ke-Xin Tang, Muhammad Hasnain Ehsan Ullah, Xiao-Bo Liao, Ling-Qing Yuan   +17 more
doaj   +1 more source