Results 101 to 110 of about 149,947 (326)

Immune-Mediated Vascular Injury and Dysfunction in Transplant Arteriosclerosis

Frontiers in Immunology, 2015
Solid organ transplantation is the only treatment for end-stage organ failure but this life-saving procedure is limited by immune-mediated rejection of most grafts.
Anna von Rossum, I. Laher, J. Choy
semanticscholar   +1 more source

Aortic Pulse Wave Velocity and Extracellular Water Expansion in Hemodialysis Patients

Artificial Organs, EarlyView.
ABSTRACT Background Pulse wave velocity (PWV), a measurement of arterial stiffness, is a risk factor for cardiovascular mortality in hemodialysis patients. Debate continues as to whether PWV is increased by volume overload. As such, we reviewed the association between volume overload and PWV.
Roohi Chhabra, Andrew Davenport
wiley   +1 more source

Targeting the Secretin Receptor in Macrophages Attenuates Silica‐Induced Pulmonary Fibrosis

Cell Proliferation, EarlyView.
Targeting macrophage SCTR mitigates integrated profibrotic, inflammatory, ER stress, and senescent pathways, preserving lung function and revealing a novel therapeutic strategy for silicosis.
Yaqian Li, Tian Li, Fuyu Jin, Shupeng Liu, Dingjie Xu, Zhongqiu Wei, Xuemin Gao, Wenchen Cai, Na Mao, Fang Yang, Haibo Zhang, Yiwei Shi, Hong Xu   +12 more
wiley   +1 more source

Validation of a microRNA profile in urine liquid biopsy with diagnostic and stratification value for bladder cancer classification, available through the open app BladdermiRaCan

Experimental Hematology & Oncology
We aimed to identify a profile of urine microRNAs (miRNAs) with diagnostic and stratification potential in the whole range of bladder cancer (BC) categories, to avoid current invasive, harmful and expensive procedures.
Julia Oto, Raquel Herranz, Emma Plana, Javier Pérez-Ardavín, David Hervás, Fernando Cana, Patricia Verger, David Ramos-Soler, Manuel Martínez-Sarmiento, César D. Vera-Donoso, Pilar Medina   +10 more
doaj   +1 more source

Fingertip skin autofluorescence as a non‐invasive marker for vascular complications in patients with type 2 diabetes

Journal of Diabetes Investigation, EarlyView.
This multicenter study demonstrated that fingertip autofluorescence, measured non‐invasively, correlates with clinical risk factors and vascular complications in patients with type 2 diabetes. Our findings suggest that fingertip autofluorescence may serve as a convenient marker for evaluating both microvascular and macrovascular complications in ...
Minoru Takeshita, Takeshi Matsumura, Aiko Arimura, Hiroyuki Takahashi, Yoshimi Muta, Shigeru Kawade, Dai Yamagami, Takahisa Deguchi, Tatsuya Kondo, Mikihiro Yamanaka, Ryoji Nagai, Daiji Kawanami, Toshihiko Yanase, Takashi Nomiyama, Yoshihiko Nishio, Eiichi Araki, Naoto Kubota   +16 more
wiley   +1 more source

Telomere length, cardiovascular risk and arteriosclerosis in human kidneys: an observational cohort study

Aging, 2015
Background Replicative senescence, associated with telomere shortening, plays an important role in aging and cardiovascular disease. The relation between telomere length, cardiovascular risk, and renal disease is unknown. Methods Our study consisted of a
K. De Vusser, Nicky Pieters, B. Janssen, E. Lerut, D. Kuypers, I. Jochmans, D. Monbaliu, J. Pirenne, T. Nawrot, M. Naesens   +9 more
semanticscholar   +1 more source

A Meta‐Analysis of the Effects of Acute Sleep Deprivation on the Cortical Transcriptome in Rodent Models

Journal of Sleep Research, EarlyView.
How does sleep deprivation affect the brain? We performed a meta‐analysis of publicly available transcriptional profiling datasets characterising the effects of sleep deprivation on cortical gene expression (n = 293 mice, 16,290 genes) and validated our results in an independent sample (n = 222 mice).
Cosette A. Rhoads, Megan H. Hagenauer, Jinglin Xiong, Erin Hernandez, Duy Manh Nguyen, Annaka Saffron, Elizabeth Flandreau, Stanley Watson Jr., Huda Akil   +8 more
wiley   +1 more source

The complex TIE between macrophages and angiogenesis [PDF]

, 2020
Macrophages are primarily known as phagocytic immune cells, but they also play a role in diverse processes, such as morphogenesis, homeostasis and regeneration.
Anghelina M., Avraham‐Davidi I., Baer C., Bailey A. S., Barnett F. H., Bonnardel J., Chakarov S., Chen L., Coffelt S. B., Corliss B. A., Cursiefen C., Daly C., Davies L. C., Davies L. C., De Palma M., De Palma M., De Palma M., De Palma M., De Palma M., De Spiegelaere W., DeFalco T., Deshmane S. L., Detry B., Dimova I., Dimova I., Eklund L., Elamaa H., Eubank T. D., Fantin A., Ferrari G., Fukuhara S., Ganta V. C., Ganta V. C., García S., Gerri C., Grunewald M., Guo L., Gurevich D. B., Hamm A., Hazan A. D., He H., Hoeffel G., Itoh M., Jetten N., Kim M., Kochhan E., Korhonen E. A., Korpelainen E. I., Krishnasamy K., Kumar A. H., Leibovich S. J., Lim H. Y., Liu C., Lucas T., Master Z., Metharom P., Michaeli S., Moldovan N. I., Moore E. M., Mueller S. B., Murdoch C., Murray P. J., Patel A. S., Polverini P. J., Potente M., Pucci F., Saharinen P., Saharinen P., Schif‐Zuck S., Schmeisser A., Seaman S. A., Seok S. H., Spiller K. L., Venneri M. A., Vestweber D., Webster N. L., West M. E. D., Willenborg S., Yamamoto S., Zajac E., Zenker D., Zhang W.   +81 more
core   +2 more sources

Cholesterol and arteriosclerosis [PDF]

, 2016
The endothelium, the layer of cells lining the interior of blood vessels, forms a complicated interface that uses signals carried by the circulating blood to modulate vascular tone, the concentration of inflammatory cells and the coagulation cascade.
openaire   +2 more sources

Molecular pathophysiology of chronic kidney disease–mineral and bone disorder: Focus on the fibroblast growth factor 23–Klotho axis and bone turnover dynamics

Experimental Physiology, EarlyView.
Abstract Chronic kidney disease–mineral and bone disorder (CKD‐MBD) is a major complication of chronic kidney disease (CKD), characterized by disruptions in mineral metabolism, abnormal bone turnover and vascular calcification, which collectively increase the risk of fractures and cardiovascular disease.
Alief Waitupu, Laras Pratiwi, Henry Sutanto, Djoko Santoso, Decsa Medika Hertanto   +4 more
wiley   +1 more source