Subclinical Infection of Macaques and Baboons with A Baboon Simarterivirus [PDF]
Simarteriviruses (Arteriviridae: Simarterivirinae) are commonly found at high titers in the blood of African monkeys but do not cause overt disease in these hosts.
Christina M Newman +2 more
exaly +5 more sources
Intraspecific variation of the hedgehog arteriviruses, which may constitute a new genus in the subfamily Heroarterivirinae of the family Arteriviridae [PDF]
Abstract We recently discovered a novel member of the family Arteriviridae, hedgehog arterivirus 1 (HhAV-1), in the brains of hedgehogs with fatal encephalitis. In this study, we classified this virus and investigated its intrahost genomic diversity using next-generation sequencing.
Akbar Dastjerdi, Alexander E Gorbalenya
exaly +4 more sources
Clinical Characterization of Host Response to Simian Hemorrhagic Fever Virus Infection in Permissive and Refractory Hosts: A Model for Determining Mechanisms of VHF Pathogenesis [PDF]
Simian hemorrhagic fever virus (SHFV) causes a fulminant and typically lethal viral hemorrhagic fever (VHF) in macaques (Cercopithecinae: Macaca spp.) but causes subclinical infections in patas monkeys (Cercopithecinae: Erythrocebus patas).
Joseph P. Cornish +18 more
doaj +3 more sources
Cytoplasmic translocation of tripartite motif-containing 28 is critical for PRRSV-induced autophagy through promoting Vps34-Beclin1 complex formation [PDF]
Autophagy, as a highly conserved cellular metabolic regulation mechanism, is a double-edged sword and plays multiple roles in viral infections processes.
Meng Chen +8 more
doaj +2 more sources
An alternative reverse genetics system for PRRS virus and its application to define the role of endocytic sorting signal in GP3 protein intracellular trafficking [PDF]
Porcine reproductive and respiratory syndrome virus (PRRSV) glycoprotein 3 (GP3) forms a heterotrimeric complex with GP2 and GP4, which is essential for viral entry and assembly.
Junyu Tang, Hiep Vu, Dongwan Yoo
doaj +2 more sources
Emergence of a PRRSV Strain Recombined From Two Modified-Live Virus Vaccines and Its Elimination From a Breeding Herd. [PDF]
Porcine reproductive and respiratory syndrome (PRRS) is one of the most challenging diseases for swine production. The PRRS virus (PRRSV) is an RNA virus that replicates via an RNA‐dependent RNA polymerase (RDRP) mechanism, which is prone to high mutation rates.
Trevisan G +10 more
europepmc +2 more sources
Genome sequence analysis of Atlantic salmon bafinivirus (ASBV) revealed a small open reading frame (ORF) predicted to encode a Type I membrane protein with an N-terminal cleaved signal sequence (110 aa), likely an envelope (E) protein.
Frederick Kibenge +3 more
doaj +1 more source
In the fall of 2019, a fatal encephalitis outbreak led to the deaths of >200 European hedgehogs (Erinaceus europaeus) in England. We used next-generation sequencing to identify a novel arterivirus with a genome coding sequence of only 43% similarity to ...
Akbar Dastjerdi +7 more
doaj +1 more source
Glycyrrhiza polysaccharides inhibits PRRSV replication
Glycyrrhiza polysaccharide (GCP) is a natural plant active polysaccharide extracted from traditional Chinese medicine licorice. In this research, we studied the antiviral activity of glycyrrhiza polysaccharide against porcine reproductive and respiratory
Youbing Yang +6 more
doaj +1 more source
Viral Metagenomics Reveals Diverse Viruses in Tissue Samples of Diseased Pigs
The swine industry plays an essential role in agricultural production in China. Diseases, especially viral diseases, affect the development of the pig industry and threaten human health.
Shixing Yang +14 more
doaj +1 more source

