Results 101 to 110 of about 18,290 (191)

Treatment outcome of intravenous artesunate in patients with severe malaria in the Netherlands and Belgium

Malaria Journal, 2012
Background Intravenous (IV) artesunate is the treatment of choice for severe malaria. In Europe, however, no GMP-manufactured product is available and treatment data in European travellers are scarce.
Kreeftmeijer-Vegter Annemarie R, van Genderen Perry J, Visser Leo G, Bierman Wouter FW, Clerinx Jan, van Veldhuizen Cees KW, de Vries Peter J   +6 more
doaj   +1 more source

Ameliorative Effects of Curcumin on Artesunate-Induced Subchronic Toxicity in Testis of Swiss Albino Male Mice

Dose-Response, 2015
India is one of the endemic areas where control of malaria has become a formidable task. Artesunate is the current antimalarial drug used to treat malaria, especially chloroquine resistant.
Ketaki R. Desai, Dhrupadsinh K. Rajput, Pragnesh B. Patel, Hyacinth N. Highland   +3 more
doaj   +1 more source

Artesunate prevents rats from the clozapine-induced hepatic steatosis and elevation in plasma triglycerides

, 2017
Yanmei Li,1,2 Ruibing Su,3 Shuqin Xu,2 Qingjun Huang,1 Haiyun Xu1,2 1The Mental Health Center, Shantou University Medical College, Shantou, Guangdong Province, People’s Republic of China; 2Department of Anatomy, Shantou University Medical College,
Li Y, Su R, Xu S, Huang Q, Xu H
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Superior Pyronaridine Single-Dose Pharmacodynamics Compared to Artesunate, Chloroquine, and Amodiaquine in a Murine Malaria Luciferase Model

, 2018
Many previous in vitro and in vivo preclinical malaria drug studies have relied on low-parasite-number drug inhibition numerically compared to the untreated controls.
Sullivan, David J, Okoth, Winter A, Dukes, Elijah J   +2 more
core   +1 more source

Artesunate induces ferroptosis by regulating MT1G and has an additive effect with doxorubicin in diffuse large B-cell lymphoma cells

Heliyon
Diffuse Large B-cell lymphoma (DLBCL) is a highly aggressive disease with heterogeneous outcomes and marked variability in the response to chemotherapy. DLBCL comprises two major subtypes: germinal centre B-cell-like (GCB) and activated B-cell-like (ABC).
Dan Xiong, Chengjie Geng, Liyi Zeng, Hua Yao, Jiewen Tan, Lan Zhang, Xiaohui Liu, Langxia Liu   +7 more
doaj   +1 more source

Addition of artesunate to chloroquine for treatment of Plasmodium falciparum malaria in Gambian children causes a significant but short-lived reduction in infectiousness for mosquitoes.

, 2004
OBJECTIVES: Combination therapy using existing anti-malarials together with artesunate (AS) has been advocated as a method to slow the spread of drug resistance.
Sutherland, Colin J, Obisike, Uche, Drakeley, Christopher J, Walraven, Gijs, Targett, Geoffrey AT, Jawara, Musa, Coleman, Rosalind, Pinder, Margaret   +7 more
core   +1 more source

Post‐Artesunate Delayed Hemolysis: Anything That Can Go Wrong Will Go Wrong—Murphy's Law

Clinical Case Reports
In patients presenting with post‐malarial anemia following intravenous artesunate treatment, post‐artesunate delayed hemolysis should be considered in the differential diagnosis, even in endemic settings.
Beliza Chemutai, Muhammed Omar Ali, Jaimin Vinod Varsani, Derrick Bary Abila, Denis Can Odonga, Paska Apiyo, Felix Bongomin   +6 more
doaj   +1 more source

Role of GRP78 inhibiting artesunate-induced ferroptosis in KRAS mutant pancreatic cancer cells

Drug Design, Development and Therapy, 2019
Kang Wang,1,* Zhengyang Zhang,1,* Ming Wang,1 Xiongfeng Cao,1 Jianchen Qi,1 Dongqing Wang,1,2 Aihua Gong,3 Haitao Zhu1,21Central Laboratory of Medical Imaging, Affiliated Hospital of Jiangsu University, Zhenjiang, 212001, People’s ...
Wang K, Zhang Z, Wang M, Cao X, Qi J, Wang D, Gong A, Zhu H   +7 more
doaj  

Efficacy and Safety of Mefloquine, Artesunate, Mefloquine-Artesunate, and Praziquantel against Schistosoma haematobium: Randomized, Exploratory Open-Label Trial [PDF]

, 2017
Background. Morbidity control of schistosomiasis relies on a single drug, praziquantel. The antimalarial drug mefloquine possesses interesting antischistosomal properties, yet no clinical studies have been performed. Methods.
Silué, Kigbafori D., Hatz, Christoph, Utzinger, Jürg, Keiser, Jennifer, N'Goran, Eliezer K., N'Guessan, Nicaise A., Adoubryn, Koffi D., Vounatsou, Penelope   +7 more
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STUDIES ON THE ANTI-CANCER PROPERTIES OF ARTESUNATE: ANTI-PROLIFERATIVE AND CYTOTOXIC EFFECTS ON BREAST AND OVARIAN CANCER CELLS

, 2014
In women, breast cancer is the most prevalent cancer diagnosis while ovarian cancer represents the most lethal gynecological neoplasm. The high incidence and mortality of these cancer types, in addition to the emergence of multi-drug resistant clones,
Greenshields, Anna L.
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