Results 91 to 100 of about 26,165 (195)

Developing Ontology Support for Human Malaria Control Initiatives [PDF]

, 2009
Malaria is one of the most common infectious diseases and an enormous public health problem in Sub-Sahara Africa, Asia and parts of America. In this paper, we discuss the development of the Human Malaria Control Ontology (HMCO) which contains general ...
Daramola Olawande, Fatumo Segun
core   +1 more source

Response to Buffet et al: Intermittent preventive anti-malarial treatment to children (IPTc): firebreak or fire trap?

, 2008
Buffet and colleagues have reviewed some of the potential benefits and drawbacks of intermittent preventive antimalarial treatment in children (IPTc).
Bojang, Kalifa, Chandramohan, Daniel, Cisse, Badara, Greenwood, Brian, Kweku, Margaret, Milligan, Paul   +5 more
core   +1 more source

Relapses of Plasmodium vivax infection usually result from activation of heterologous hypnozoites. [PDF]

, 2007
BACKGROUND: Relapses originating from hypnozoites are characteristic of Plasmodium vivax infections. Thus, reappearance of parasitemia after treatment can result from relapse, recrudescence, or reinfection.
Anderson, T J C, Carlton, J, Day, N P J, Guthmann, J P, Imwong, M, Kim, J R, Looareesuwan, S, Nair, S, Nandy, A, Nosten, F, Pukrittayakamee, S, Snounou, G, Sudimack, D, Tanomsing, N, White, N J   +14 more
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The Economic Costs of Malaria in Children in three Sub-Saharan Countries: Ghana, Tanzania and Kenya. [PDF]

, 2013
Malaria causes significant mortality and morbidity in sub-Saharan Africa (SSA), especially among children less than five years of age (U5 children).
Constenla, Dagna, Lindner, Leandro, Sauboin, Christophe, Sicuri, Elisa, Vieta, Ana   +4 more
core   +2 more sources

Safety and pharmacokinetic properties of a new formulation of parenteral artesunate in healthy Thai volunteers

Malaria Journal
Background Parenteral artesunate is the first-line therapy for severe malaria. Artesunate, in its current formulation, must be prepared immediately before administration by first dissolving in sodium bicarbonate solution and then diluting in saline.
Joel Tarning, Borimas Hanboonkunupakarn, Richard M. Hoglund, Kesinee Chotivanich, Mavuto Mukaka, Sasithon Pukrittayakamee, Nicholas P. J. Day, Nicholas J. White, Arjen M. Dondorp, Podjanee Jittamala   +9 more
doaj   +1 more source

Randomized controlled trial of artesunate or artemether in Vietnamese adults with severe falciparum malaria

Malaria Journal, 2010
Background Both artemether and artesunate have been shown to be superior to quinine for the treatment of severe falciparum malaria in Southeast Asian adults, although the magnitude of the superiority has been greater for artesunate than artemether. These
White Nicholas J, Chuong Ly V, Sinh Dinh X, Chau Tran TH, Mai Nguyen TH, Day Nicholas, Tuan Phung Q, Phu Nguyen H, Farrar Jeremy, Hien Tran T   +9 more
doaj   +1 more source

Artemisinin: From Chinese Herbal Medicine to Modern Chemotherapy [PDF]

, 2019
Malaria is a disease that has blighted humankind since early times. The first antimalarial treatment available to Europeans was the dried bark of the cinchona tree from Peru. The main problem in its use was adulteration by other material.
Butler, Anthony
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Efficacy of three artemisinin combination therapies for the treatment of uncomplicated Plasmodium falciparum malaria in the Republic of Congo. [PDF]

BACKGROUND: Presented here are the results of a comparative trial on the efficacy of three artemisinin-based combinations conducted from May to October 2004, in Pool Province, Republic of Congo.
van den Broek, I, Kitz, C, Al Attas, S, Libama, F, Balasegaram, M, Guthmann, J P   +5 more
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A reiterative method for calculating the early bactericidal activity of antituberculosis drugs.

, 2002
Studies of early bactericidal activity (EBA) are important in the rapid evaluation of new antituberculosis drugs. Historically, these have concentrated on the log fall in the viable count in sputum during the first 48 hours of therapy.
Charalambous, Bambos M, Gillespie, Stephen H, Gosling, Roland D   +2 more
core   +1 more source

Nanoparticle Delivery of Artesunate Enhances the Anti-tumor Efficiency by Activating Mitochondria-Mediated Cell Apoptosis

Nanoscale Research Letters, 2017
Artemisinin and its derivatives were considered to exert a broad spectrum of anti-cancer activities, and they induced significant anti-cancer effects in tumor cells.
Rui Liu, Xiwei Yu, Chang Su, Yijie Shi, Liang Zhao   +4 more
doaj   +1 more source