Results 91 to 100 of about 18,290 (191)

Intravenous Artesunate for Severe Malaria [PDF]

, 2010
OBJECTIVE: To review the pharmacodynamics and pharmacotherapeutic use of intravenous artesunate for the treatment of severe malaria. DATA SOURCES: Literature was retrieved through PubMed (1999 March 2010), MEDLINE (1996 March 2010), and the Centers for ...
Arguin, Paul M., Hess, Karl M., Jeffery A Goad, Goad, Jeffery A., Paul M Arguin, Karl M Hess   +5 more
core   +1 more source

Artesunate [PDF]

Reactions Weekly, 2020
  +4 more sources

A stratified random survey of the proportion of poor quality oral artesunate sold at medicine outlets in the Lao PDR – implications for therapeutic failure and drug resistance

Malaria Journal, 2009
Background Counterfeit oral artesunate has been a major public health problem in mainland SE Asia, impeding malaria control. A countrywide stratified random survey was performed to determine the availability and quality of oral artesunate in pharmacies ...
Vongsack Latsamy, Khounsaknalath Lamphet, Hostetler Dana, Mildenhall Dallas C, Nyadong Leonard, Hampton Christina Y, Insixiengmay Vongsavanh, Phommavong Khamlieng, Manolin Ot, Fernández Facundo M, Green Michael D, Sengaloundeth Sivong, Phompida Samlane, Vanisaveth Viengxay, Syhakhang Lamphone, Newton Paul N   +15 more
doaj   +1 more source

Efficacy and safety of mefloquine, artesunate, mefloquine-artesunate, and praziquantel against Schistosoma haematobium: randomized, exploratory open-label trial [PDF]

, 2010
BACKGROUND: Morbidity control of schistosomiasis relies on a single drug, praziquantel. The antimalarial drug mefloquine possesses interesting antischistosomal properties, yet no clinical studies have been performed. METHODS: We conducted a randomized,
Utzinger, J, N'Guessan N. A.,, Keiser, J., Utzinger, J., Vounatsou, P, N'Goran, E K, N'Goran E. K.,, N'Guessan, N A, Hatz, C., Hatz, C, Adoubryn, K. D., Adoubryn, K D, Silué, K. D., Keiser, J, Vounatsou, P., Silué, K D   +15 more
core   +1 more source

Artesunate-induced hemolysis in severe complicated malaria – A diagnostic challenge: A case report and literature review of anemia in malaria

, 2021
Malaria infection, which results due to the parasitic protozoan Plasmodium, has several known etiologies of hemolytic anemia as a possible complication in cases such as concurrent G6PD deficiency, severe parasitemia, or use of parenteral antimalarials ...
Muhammad Bilal Jamshaid (17269180), Sundus Sardar (14571097), Mhd Baraa Habib (11721774), Adnan Humam Hajjar (17269183), Anand Kartha, Khalid Farooqui, Muhammad Bilal Jamshaid, Tasnim Abdalla, Ahmed Abdelhadi (17269177), Munir Abu Ageila, Tasnim Abdalla (4633825), Anand Kartha (9658520), Khalid Farooqui (14777752), Mhd Baraa Habib, Mohammed Abdurabu (17269174), Mohammed Abdurabu, Adnan Humam Hajjar, Munir Abu Ageila (17269186), Sundus Sardar, Ahmed Abdelhadi   +19 more
core   +1 more source

Safety and pharmacokinetic properties of a new formulation of parenteral artesunate in healthy Thai volunteers

Malaria Journal
Background Parenteral artesunate is the first-line therapy for severe malaria. Artesunate, in its current formulation, must be prepared immediately before administration by first dissolving in sodium bicarbonate solution and then diluting in saline.
Joel Tarning, Borimas Hanboonkunupakarn, Richard M. Hoglund, Kesinee Chotivanich, Mavuto Mukaka, Sasithon Pukrittayakamee, Nicholas P. J. Day, Nicholas J. White, Arjen M. Dondorp, Podjanee Jittamala   +9 more
doaj   +1 more source

Randomized controlled trial of artesunate or artemether in Vietnamese adults with severe falciparum malaria

Malaria Journal, 2010
Background Both artemether and artesunate have been shown to be superior to quinine for the treatment of severe falciparum malaria in Southeast Asian adults, although the magnitude of the superiority has been greater for artesunate than artemether. These
White Nicholas J, Chuong Ly V, Sinh Dinh X, Chau Tran TH, Mai Nguyen TH, Day Nicholas, Tuan Phung Q, Phu Nguyen H, Farrar Jeremy, Hien Tran T   +9 more
doaj   +1 more source

Clinical determinants of early parasitological response to ACTs in African patients with uncomplicated falciparum malaria : a literature review and meta-analysis of individual patient data [PDF]

, 2015
Artemisinin-resistant Plasmodium falciparum has emerged in the Greater Mekong sub-region and poses a major global public health threat. Slow parasite clearance is a key clinical manifestation of reduced susceptibility to artemisinin.
Wwarn Artemisinin based Combination Therapy Africa Baseline Stud,
core   +1 more source

Nanoparticle Delivery of Artesunate Enhances the Anti-tumor Efficiency by Activating Mitochondria-Mediated Cell Apoptosis

Nanoscale Research Letters, 2017
Artemisinin and its derivatives were considered to exert a broad spectrum of anti-cancer activities, and they induced significant anti-cancer effects in tumor cells.
Rui Liu, Xiwei Yu, Chang Su, Yijie Shi, Liang Zhao   +4 more
doaj   +1 more source

Measuring the Plasmodium falciparum HRP2 protein in blood from artesunate-treated malaria patients predicts post-artesunate delayed hemolysis

, 2017
Artesunate, the recommended drug for severe malaria, rapidly clears the malaria parasite from infected patients but frequently induces anemia-called post-artesunate delayed hemolysis (PADH)-for which a simple predictive test is urgently needed.
Kendjo, E, Gay, F, Ghose, A, Woodrow, Charles, Jauréguiberry, S, Bonnefoy, S, Plewes, Katherine, Houzé, S, Argy, N, Kingston, HWF, Langui, D, Mouri, O, Chartrel, N, French Artesunate Working Group, Danis, M, Perillaud, C, Hassan, MMU, Thellier, M, Mérens, A, Roussel, C, Larréché, S, Dondorp, Adrianus M (Arjen), Biligui, S, Hossain, MA, Buffet, PA, Ndour, PA   +25 more
core   +1 more source