Results 191 to 200 of about 589,621 (302)

Gasdermin D‐Mediated Pyroptosis Exerts Two Opposite Effects of Resisting Enzymatic Digestion and Expanding Inflammatory Response in Acute Pancreatitis

Advanced Science, EarlyView.
Gasdermin D (GSDMD) does not only reduce pancreatic enzyme synthesis but also induces pancreatic acinar cells to express mucin 1 (MUC1), which forms a barrier to prevent digestive enzyme‐mediated digestion. However, GSDMD can promote the secretion of inflammatory cytokines by macrophages and aggravate pancreatic histological injury by expanding ...
Chaoxu Liu, Ning Liang, Chen Wu, Zhaoyan Qiu, Qian Huang, Xiaolong Wei, Shurong Zhang, Shuanghong Lei, Tao Yang, Gang Wang, Qian Wang   +10 more
wiley   +1 more source

Where Do We Stand in the Management of Rheumatoid Arthritis Ahead of EULAR/ACR 2025? [PDF]

Clin Pract
Vlad AL, Popazu C, Lescai AM, Voinescu DC, Baltă AAȘ.   +4 more
europepmc   +1 more source

Rheumatoid Arthritis [PDF]

Mayo Clinic Proceedings, 1988
openaire   +2 more sources

Macrophage‐Mediated Transport of Insoluble Indirubin Induces Hepatic Injury During Intestinal Inflammation

Advanced Science, EarlyView.
Plant‐derived bioactive molecules with low solubility and permeability induce hepatocyte injury, though the mechanisms driving their hepatic effects remain poorly understood. This study identifies a novel transport pathway in which poorly soluble indirubin accumulates in the liver via macrophage‐mediated uptake in Peyer's patches, exacerbating hepatic ...
Yiqi Xu, Jingchun Shi, Heung‐Lam Mok, Cheng Lyu, Junbang Chen, Chunhua Huang, Hongyan Qin, Chengyuan Lin, Hor‐Yue Tan, Zhaoxiang Bian   +9 more
wiley   +1 more source

Disease knowledge and quality of life among rheumatoid arthritis patients: a cross-sectional study. [PDF]

BMC Rheumatol
Albiss L, Muflih S, Hijazi B, Alshogran OY, Al-Qerem W, Khurmah MA, Al-Azayzih A, Shatnawi H, Shakatira Y.   +8 more
europepmc   +1 more source

Bidirectional Interaction Between the Brain and Bone in Traumatic Brain Injury

Advanced Science, EarlyView.
Traumatic brain injury (TBI) disrupts the blood–brain barrier and activates neuroimmune responses, causing metabolic disturbances and long‐term bone mass loss. Concurrent fractures accelerate healing and enhance osteogenesis but disrupt regulatory mechanisms, leading to altered bone dynamics and exacerbating neuroinflammation, complicating recovery ...
Wei Zhang, Jun Zou, Lingli Zhang
wiley   +1 more source

GeneHarmony: A Knowledge-Based Tool for Biomarker Discovery in Disease: Sjögren's Disease vs. Rheumatoid Arthritis and Systemic Lupus Erythematosus. [PDF]

Int J Mol Sci
Beckman MF, Alexander A, Mougeot JC, Bahrani Mougeot F.   +3 more
europepmc   +1 more source

In Situ Valence Engineering of Copper Silicate Nanozymes with Enhanced Peroxidase‐Like Catalytic Activity for Oral Disease Detection

Advanced Science, EarlyView.
A novel copper silicate nanozyme (CSHSs‐Ar) with high peroxidase‐like catalytic activity and great catalytic specificity is well developed using a facile in situ valence‐engineered approach. The well‐developed CSHSs‐Ar nanozyme‐involved system can be utilized and employed as an efficient colorimetric sensor for the detection of volatile sulfur ...
Xiaocan Liu, Zhen Ding, Chengjing Xu, Jinming Zhang, Yufu Liu, Tianyan Chen, Shuang Dai, Xingfu Bao, Min Hu, Zhen Liu   +9 more
wiley   +1 more source

Sociodemographic and economic barriers to initial specialist care for patients with rheumatoid arthritis: a scoping review. [PDF]

BMC Rheumatol
Ainsworth J, Bolic M, Ismail I, Mohammadpour Z, Wood J.   +4 more
europepmc   +1 more source