Results 31 to 40 of about 573,431 (299)

NLRP3 inflammasome activation mechanism and its role in autoimmune liver disease

Acta Biochimica et Biophysica Sinica, 2022
The NLRP3 inflammasome is a multiprotein binding compound comprising NLRP3, connector protein ASC, and effector protein pro-caspase-1. When the NLRP3 inflammasome senses a danger signal from the host or pathogen, activated caspase-1 cleaves the ...
Guan Yanling, Gu Yiyue, Li Hao, Liang Bo, Han Chenchen, Zhang Yu, Liu Qian, Wei Wei, Ma Yang   +8 more
doaj   +1 more source

Dynamic plantar loading index detects altered foot function in individuals with rheumatoid arthritis but not changes due to orthotic use [PDF]

, 2014
Background Altered foot function is common in individuals with rheumatoid arthritis. Plantar pressure distributions during gait are regularly assessed in this patient group; however, the association between frequently reported magnitude-based pressure ...
Baeten, Elien, Gibson, Kellie. S., Hendry, Gordon J., Steultjens, Martijn P., Telfer, Scott, Turner, Deborah E., Woodburn, James   +6 more
core   +1 more source

Establishment of a qualified integrated care system after total knee arthroplasty as a role of regional rheumatoid and degenerative arthritis centers

BMC Geriatrics, 2022
Background The geriatric population and advanced knee osteoarthritis are rapidly increasing in Korea, and the socioeconomic burden of total knee arthroplasty (TKA) is increasing.
Eun Young Han, Sang Rim Kim, Kye Hee Cho, Sang Hee Im   +3 more
doaj   +1 more source

Hybrid computational modeling highlights reverse warburg effect in breast cancer-associated fibroblasts

Computational and Structural Biotechnology Journal, 2023
Cancer-associated fibroblasts (CAFs) are amongst the key players of the tumor microenvironment (TME) and are involved in cancer initiation, progression, and resistance to therapy.
Sahar Aghakhani, Sacha E Silva-Saffar, Sylvain Soliman, Anna Niarakis   +3 more
doaj  

‘The current mental health status of children and young people with JIA, and their wider family’: a charity partner collaboration survey

Pediatric Rheumatology Online Journal, 2023
Background This paper presents insight into the scale of mental health concerns for families who have a child or young person with a diagnosis of Juvenile Idiopathic Arthritis (JIA) living in any of the four nations of the United Kingdom (UK).
Polly Livermore, S. Ainsworth, R. Beesley, S. Douglas, E. Earle, D. Wilson, L. Woolley, J. Clinch   +7 more
doaj   +1 more source

Effectiveness of self-management interventions in inflammatory arthritis: a systematic review informing the 2021 EULAR recommendations for the implementation of self-management strategies in patients with inflammatory arthritis

RMD Open, 2021
Objective To perform a systematic review (SR) on the effectiveness of self-management interventions, in order to inform the European League Against Rheumatism Recommendations for its implementation in patients with inflammatory arthritis (IA).Methods The
Andréa Marques, Ailsa Bosworth, Eduardo Santos   +2 more
doaj   +1 more source

Polyautoimmunity in systemic lupus erythematosus patients: New insights from a cross-sectional study

Journal of Translational Autoimmunity, 2023
Objective: To assess the frequency of polyautoimmunity (PolyA) in a cohort of Colombian patients with systemic lupus erythematosus (SLE) and to identify associated factors.
Pedro Santos-Moreno, Julián Arias-Aponte, Gabriel-Santiago Rodríguez-Vargas, Paula Daniela Nieto-Zambrano, Laura Villarreal, Linda Ibatá, Susan Martinez, Jaime-Andrés Rubio-Rubio, Pedro Rodríguez, Adriana Rojas-Villarraga   +9 more
doaj  

Evaluation of central corneal thickness and corneal curvature in patients with rheumatoid arthritis

Asian Journal of Medical Sciences, 2022
Background: Rheumatoid arthritis is an autoimmune disease. It is a chronic disease that causes symmetrical deforming type of polyarthritis. Rheumatoid arthritis most commonly involves the anterior segment of the eye. It causes keratoconjunctivitis sicca,
Rubina Huda , Syed Ali Nasar Waris , Sankar Kumar T , Panchapakesa Rajendran C   +3 more
doaj   +1 more source

Preclinical rheumatoid arthritis and rheumatoid arthritis prevention

Current Opinion in Rheumatology, 2020
Purpose of reviewThis review is to provide an update on the current understanding of rheumatoid arthritis (RA) development related to disease development prior to the onset clinically apparent synovitis (i.e. Pre-RA), and opportunities for disease prevention.Recent findingsA growing number of studies have demonstrated that serum elevations of ...
Hyoun-Ah Kim, Hyoun-Ah Kim, Leah F Bettner, H Karl Greenblatt, Kevin D. Deane   +4 more
openaire   +4 more sources

DAS28: a useful instrument to monitor infliximab treatment in patients with rheumatoid arthritis [PDF]

, 2005
The Disease Activity Score using 28 joint counts (DAS28) has been developed in a cohort of patients with rheumatoid arthritis in which only conventional anti-rheumatic treatments were used. It has extensively been validated to monitor disease activity in
Fransen, Jaap, van Riel, Piet LCM
core   +2 more sources