Results 81 to 90 of about 60,768,312 (388)
Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona +4 more
wiley +1 more source
No abstract available.
Stephen Kruger
doaj +1 more source
Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells
Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura +8 more
wiley +1 more source
Bullying, a pernicious affliction that indiscriminately afflicts students of all ages and backgrounds, is a scourge that demands our attention. It involves a pattern of conduct whereby one individual is repeatedly targeted for aggression by one or more ...
Shweta Singh, Seema Singh
doaj +1 more source
Cancer cell death induced by the NAD antimetabolite Vacor discloses the antitumor potential of SARM1
Vacor, a compound converted into the toxic metabolite Vacor adenine dinucleotide (VAD) by the nicotinamide salvage pathway enzymes NAMPT and NMNAT2, exhibits antitumor activity by inducing rapid and complete NAD depletion. We report that Vacor toxicity is limited to cell lines expressing high levels of SARM1, a NAD glycohydrolase.
Giuseppe Ranieri +5 more
wiley +1 more source
The article is devoted to the historiographical review of publications dated by late XIX - early XXI centuries and containing information about amulets and talismans of the Egyptian faience, found in the settlements and burial grounds in Rostovskaya ...
S B Burkov, S M-A Gadalrab
doaj +1 more source
Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley +1 more source
St. Thomas Aquinas, Dramatist? [PDF]
The article begins with the statement that there is one aspect of St Thomas’s work that has not received due scrutiny as a literary form, one with solid dramatic qualities and structure: the Article.
Eric McLuhan
doaj

