Results 101 to 110 of about 176,243 (319)

RADA16 and SAAP148 Peptide‐Modified Collagen Self‐Assembled Hydrogels for Accelerated Healing of Infected Wounds

Advanced Science, EarlyView.
Collagen type I (Col I) is integrated with self‐assembling peptide RADA16 and loaded with anti‐bacterial peptide SAAP148 to develop a self‐assembled nano‐microstructure hydrogel (Col I‐RADA16‐SAAP148, CRS) without chemical cross‐linkers. CRS exhibits excellent mechanical properties, sustained SAAP148 release to inhibit bacterial infection, macrophage ...
Qian Liu, Jiawei Wu, Ho‐Pan Bei, Yufei Chen, Yifan Zhang, Xueliang Peng, Fulin Chen, Xin Zhao, Zhuoyue Chen   +8 more
wiley   +1 more source

Ultramodern natural and synthetic polymer hydrogel scaffolds for articular cartilage repair and regeneration

BioMedical Engineering OnLine
Articular cartilage injury is a serious bone disease that can result in disabilities. With the rapid increase in the aging population, this disorder has become an increasingly important public health issue.
Chun-Sheng Li, Yan Xu, Juan Li, Shu-Hao Qin, Shao-Wen Huang, Xue-Mei Chen, Yi Luo, Cheng-Tao Gao, Jian-Hui Xiao   +8 more
doaj   +1 more source

Fresh Osteochondral Allograft Transplantation for Treatment of Articular Cartilage Defects of the Knee

Arthroscopy Techniques, 2016
Articular cartilage damage of the knee can cause severe morbidity. Owing to its avascular nature, articular cartilage has limited potential for self-healing and increased propensity to progress to osteoarthritis.
Chase S. Dean, M.D., Jorge Chahla, M.D., Raphael Serra Cruz, M.D., Robert F. LaPrade, M.D., Ph.D.   +3 more
doaj   +1 more source

Spatial Transcriptomics of TMJ Reveals a Remodeling Fibroblast‐Immune Microenvironment Driving Arthritis Pain

Advanced Science, EarlyView.
Spatial transcriptomics reveals a remodeled fibroblast‐immune microenvironment in the temporomandibular joint (TMJ) during arthritis. By combining seqFISH with genetic mouse models, this study uncovers TMJ spatial cell atalas, macrophage‐fibroblast crosstalk, and cytokine signaling pathways driving TMJ inflammation and pain.
Ziying Lin, Supawadee Jariyasakulroj, Yang Shu, Jingyi Chen, Qing Chang, Pao‐Fen Ko, Yuyueyang Qiu, Feixiang Chen, David Ahn, Zhen Zhao, Jian‐Fu Chen   +10 more
wiley   +1 more source

Role of Platelet-Rich Plasma in Articular Cartilage Injury and Disease [PDF]

, 2014
Randy Mascarenhas, Bryan M. Saltzman, Lisa A. Fortier, Brian J. Cole   +3 more
openalex   +1 more source

Functional roles of COMP and TSP-4 in articular cartilage and their relevance in osteoarthritis [PDF]

, 2021
Kathrin Maly
openalex   +1 more source

circNR3C2 promotes chondrogenic differentiation and cartilage repair of human adipose‐derived stem cells via the hsa‐miR‐647/SOX9 pathway

Animal Models and Experimental Medicine, EarlyView.
The hypothesis diagram illustrates the function and mechanism of circNR3C2: circNR3C2 overexpression can up‐regulate COL2, Aggrecan and SOX9 expression, and regulate chondrogenic differentiation of hADSCs by targeting hsa‐miR‐647. Abstract Background Human adipose‐derived stem cells (hADSCs) are seed cells with application prospects in cartilage repair.
Dabiao Hou, Huajun Wang, Hao Guo, Dongbin Luo, Xiaofei Zheng, Simin Luo   +5 more
wiley   +1 more source

Advances in understanding cartilage remodeling [v1; ref status: indexed, http://f1000r.es/5e6]

F1000Research, 2015
Cartilage remodeling is currently among the most popular topics in osteoarthritis research. Remodeling includes removal of the existing cartilage and replacement by neo-cartilage.
Yefu Li, Lin Xu
doaj   +1 more source

Effects of immobilization on articular cartilage: Autohistoradiographic findings with S35 [PDF]

The effect of immobilization on the articular cartilage of rabbits was studied by light microscope. The knee joint of each rabbit was immobilized in a plaster in a position midway between flexion and extension for a 10 to 120 days period.
Desantis, E., Digiovanni, C.
core   +1 more source

Aging, osteoarthritis and transforming growth factor-beta signaling in cartilage. [PDF]

, 2006
Osteoarthritis is a common malady of the musculoskeletal system affecting the articular cartilage. The increased frequency of osteoarthritis with aging indicates the complex etiology of this disease, which includes pathophysiology and joint stability ...
Reddi, A Hari
core   +1 more source