Results 51 to 60 of about 43,162 (263)

The Biologic Approach for Managing Cartilage Injury: Where are We Now™

Orthopaedic Journal of Sports Medicine, 2023
Articular cartilage or Hyaline cartilage consists of 95% type 2 collagen, water, proteoglycans and chondrocytes. Cartilage functions to decrease friction, distribute loads, resists shear/compression, and also as a shock-absorbing cushion.
Evan
doaj   +1 more source

Harnessing Phase Separation for the Development of High‐Performance Hydrogels

Advanced Science, EarlyView.
ABSTRACT Hydrogels are indispensable for the development of next‐generation bioelectronics, soft robotics, and biomedical devices, where their mechanical properties determine performance and reliability. Among strategies to enhance hydrogel mechanics, phase separation enables controlled heterogeneity resulting in gel networks that are reinforced by ...
Yue Shao, Yiming Ma, Baihao Shao, Molly M. Stevens   +3 more
wiley   +1 more source

Does radiofrequency ablation (RFA) epiphysiodesis affect adjacent joint cartilage?

Journal of Children's Orthopaedics, 2016
Purpose To test the hypothesis that epiphysiodesis made with radiofrequency ablation (RFA) is a safe procedure that disrupts the growth plate without damaging the adjacent joint articular cartilage.
Juan Manuel Shiguetomi-Medina, O. Rahbek, A. A. H. Abood, H. Stødkilde-Jørgensen, J. L. Ramírez Garcia-Luna, B. Møller-Madsen   +5 more
doaj   +1 more source

The Intra-Articular Hematoma Immediately after Ankle Fracture Causes Cartilage Damage That is Partially Attenuated by Anti-Inflammatory Agents

Foot & Ankle Orthopaedics, 2020
Category: Ankle Arthritis; Basic Sciences/Biologics Introduction/Purpose: Post-traumatic osteoarthritis (PTOA) is a frequent cause of disability. The most common predisposing factor for ankle PTOA is intra-articular ankle fracture.
Samuel B. Adams MD, Nicholas B. Allen, Bijan Abar   +2 more
doaj   +1 more source

Identification of Naturally Occurring Cartilage Damage in the Equine Distal Interphalangeal Joint Using Low-Field Magnetic Resonance Imaging and Magnetic Resonance Arthrography

Frontiers in Veterinary Science, 2020
Objectives: To describe detectable and non-detectable naturally occurring cartilage damage of the equine distal interphalangeal (DIP) joint using plain magnetic resonance (MR) imaging and gadolinium and saline MR arthrography. The second objective was to
Claudia van Zadelhoff, Tobias Schwarz, Sionagh Smith, Antoine Engerand, Sarah Taylor   +4 more
doaj   +1 more source

A Biomimetic Lubricant Captures Hyaluronic Acid In Situ to Regenerate Cartilage: From Bench to Bedside

Advanced Science, EarlyView.
(a) The outstanding lubricative properties of natural articular cartilage arise from a composite coating composed of HA, lubricin, and phospholipids at its surface. Notably, lubricin facilitates the enrichment of synovial HA onto cartilage surfaces, and HA complexes with phospholipids, a key component to maintain extremely low friction under high ...
Yongan Lin, Zijian Yan, Jiayi Chen, Xiaochao Wang, Ruibin Lin, Yunqi Fu, Zhaoying Lv, Bohui Wu, Xuewei Cao, Renjian Xie, Ming Dong, Chenxiao Zheng, Li Ren   +12 more
wiley   +1 more source

Environmental high temperature (heat stroke) causes articular cartilage damage in vivo and in vitro

Ecotoxicology and Environmental Safety
Heatstroke (HS) is gradually becoming a major challenge in the field of global public health with the trend of global warming. In recent years, extreme high-temperature weather events have occurred frequently in the world, which directly led to a ...
Sun yingfei, Yang feng, Ma haoning
doaj   +1 more source

Quantitative evaluation of very early cartilage damage in experimental osteoarthritis using scanning electron microscopy

Advances in Rheumatology, 2022
Objective To describe parametric changes observed using scanning electron microscopy (SEM) in very early stages in posttraumatic osteoarthritis (OA) models in mice.
Virgínia Cláudia Carneiro Girão-Carmona, Mirna Marques Bezerra, Fernanda Maria Aragão Ximenes Porto, Ana Carolina Matias Dinelly Pinto, Rodolfo de Melo Nunes, Anelise Maria Costa Vasconcelos Alves, Claudio Cabral Campello, Ana Caroline Rocha de Melo Leite, Gerly Anne de Castro Brito, Francisco Airton Castro da Rocha   +9 more
doaj   +1 more source

WTAP‐Mediated m6A Modification Targets the LRP1‐Lipid Metabolism Axis to Regulate Joint Cartilage Regeneration

Advanced Science, EarlyView.
WTAP drives cartilage regeneration by activating an LRP1‐dependent lipid metabolic program in macrophages, enhancing IL‐10 and TGF‐β secretion to promote chondrogenic differentiation. Leveraging this mechanism, virtual screening identifies LRP1‐targeting compounds that effectively stimulate cartilage repair, highlighting a druggable epigenetic ...
Chenyan Huang, Chenyu Deng, Zhengrong Gao, Chen Chen, Huimin Zheng, Yue Yang, Yan Wei   +6 more
wiley   +1 more source

A Piezo‐Mimetic Ionic Hydrogel Harnessing Joint Motion for Cartilage Repair

Advanced Science, EarlyView.
A piezo‐mimetic ionic hydrogel converts mechanical deformation into bioactive ionic currents via stress‐induced asymmetric ion migration. Coupled with sustained Mg2+ release, this mechano‐electrochemical platform bridges mechanical loading and cellular signaling, enabling load‐adaptive stimulation and enhanced cartilage regeneration. ABSTRACT Articular
Chenyuan Gao, Xinyu Wang, Zhifeng Wu, Xinya Zhang, Xiao Geng, Ti Zhang, Yue Wang, Hongwei Xia, Jun Zhang, Xianbo Qiu, Cuiru Sun, Yingjie Yu, Wenli Dai, Hua Tian, Qing Cai   +14 more
wiley   +1 more source