Results 61 to 70 of about 139,262 (370)

Surface damage of bovine articular cartilage-off-bone: the effect of variations in underlying substrate and frequency

BMC Musculoskeletal Disorders, 2018
Background Changes in bone mineral density have been implicated with the onset of osteoarthritis, but its role in inducing failure of articular cartilage mechanically is unclear.
Humaira Mahmood, Duncan E. T. Shepherd, Daniel M. Espino   +2 more
doaj   +1 more source

Heterogeneity of mesenchymal stem cells in cartilage regeneration: from characterization to application

npj Regenerative Medicine, 2021
Articular cartilage is susceptible to damage but hard to self-repair due to its avascular nature. Traditional treatment methods are not able to produce satisfactory effects.
Kangkang Zha, Xu Li, Zhen Yang, Guangzhao Tian, Zhiqiang Sun, Xiang Sui, Yongjing Dai, Shuyun Liu, Quanyi Guo   +8 more
doaj   +1 more source

Future directions for the management of pain in osteoarthritis. [PDF]

, 2014
Osteoarthritis (OA) is the predominant form of arthritis worldwide, resulting in a high degree of functional impairment and reduced quality of life owing to chronic pain. To date, there are no treatments that are known to modify disease progression of OA
Aigner T, Anasuya Kuttapitiya, Balanescu AR, Bannuru RR, Chou R, da Costa BR, Danielsson L, Fanelli A, Fransen M, Haviv B, Huskisson EC, Lim YZ, Mankin HJ, McAlindon TE, Merlotti D, Nguyen US, Nidhi Sofat, Pelletier JP, Sagar DR, Sellers RS, Sofat N, Tannenbaum H, Wajed J, Wakitani S   +23 more
core   +1 more source

Considerations in hiPSC-derived cartilage for articular cartilage repair

Inflammation and Regeneration, 2018
Background A lack of cell or tissue sources hampers regenerative medicine for articular cartilage damage. Main text We review and discuss the possible use of pluripotent stem cells as a new source for future clinical use.
Akihiro Yamashita, Yoshihiro Tamamura, Miho Morioka, Peter Karagiannis, Nobuyuki Shima, Noriyuki Tsumaki   +5 more
doaj   +1 more source

The Relationship Between Proteoglycan Loss, Overloading-Induced Collagen Damage, and Cyclic Loading in Articular Cartilage

Cartilage, 2019
Objective The interaction between proteoglycan loss and collagen damage in articular cartilage and the effect of mechanical loading on this interaction remain unknown.
Lorenza Henao-Murillo, M. Pastrama, Keita Ito, C. V. van Donkelaar   +3 more
semanticscholar   +1 more source

Plebeian Sage (Salvia plebeia R. Br) Extract Ameliorates Inflammation and Cartilage Degradation in Surgically Induced Osteoarthritis Rats

Applied Sciences, 2022
Osteoarthritis (OA), the most prevalent articular disease with the clinical syndrome of joint pain accompanied by varying degrees of functional limitation, reduces the quality of elderly life.
Eun-Byeol Lee, Ji-Hye Choi, Sae-Kwang Ku, Beom-Rak Choi, Hwan-Hee Jang, Heon-Woong Kim, Jeong-Sang Lee, Sung-Hyen Lee   +7 more
doaj   +1 more source

Management of Osteoarthritis with Avocado/Soybean Unsaponifiables. [PDF]

, 2015
Osteoarthritis (OA) is a painful and life-altering disease that severely limits the daily activity of millions of Americans, and is one of the most common causes of disability in the world. With obesity on the rise and the worlds population living longer,
Bhatti, Simi, Christiansen, Blaine, Emami, Shahin, Goudarzi, Ramin   +3 more
core   +1 more source

Histological Evaluation Of Articular Cartilage Damage Following Radiofrequency Chondroplasty

European Journal of Medical and Health Sciences, 2020
Background: Radiofrequency probes have been used extensively in various arthroscopic procedures. Measurable cartilage damage occurs after radiofrequency probe application. However, the histological changes of cartilage damage following radiofrequency chondroplasty have not been extensively studied. Materials & Methods: Articular cartilage ...
Vidhya Lakshmi S., Rufus V. Raj, Santhosh Sahanand   +2 more
openaire   +2 more sources

Preferences for post‐traumatic osteoarthritis prevention strategies in individuals with anterior cruciate ligament injury

Arthritis Care &Research, Accepted Article.
Objectives There is growing interest in evaluating new strategies to delay or prevent post‐traumatic osteoarthritis (PTOA) in individuals who have sustained anterior cruciate ligament (ACL) injury. This study sought to determine characteristics of potential treatments that are acceptable to patients with ACL injury.
Kevin Kennedy, Lily Waddell, Adam Easterbrook, Jeffrey N. Katz, Cale Jacobs, Morgan Jones, Faith Selzer, Elena Losina, Liana Fraenkel, Nick Bansback   +9 more
wiley   +1 more source

In Vitro Models For Cell-Based Cartilage Regeneration [PDF]

, 2014
__Abstract__ Covering the ends of the long bones in articular joints, cartilage allows smooth, gliding movement of the joints and distributes load evenly across the joint surface.
Vries-Van Melle, M.L. (Marloes) de
core