Results 81 to 90 of about 650,432 (282)

Enhancing the Effectiveness of Social Dialogue Articulation in Europe (EESDA) Project No. VS/2017/0434 Social Dialogue Articulation and Effectiveness: Country Report for France [PDF]

open access: yes, 2017
This report presents a country study analysing the articulation and effectiveness of social dialogue in France. The methodological approach relies on desk research and semi-structured interviews with social partners in France, aiming at obtaining deeper ...
Akgüç, Mehtap   +2 more
core  

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

Spectrographs Speech Measures and Audiologic Findings of Young Children with Unilateral Cleft Lip and Palate

open access: yesTurkish Journal of Orthodontics, 2008
The aim of the study was to assess the audiologic and the speech status of operated unilateral cleft preschooler patients who have no orthodontic, otologic, and speech therapy.
Fatih Ögüt   +4 more
doaj   +1 more source

The Role of Temporal Modulation in Sensorimotor Interaction

open access: yesFrontiers in Psychology, 2019
How do we align the distinct neural patterns associated with the articulation and the acoustics of the same utterance in order to guide behaviors that demand sensorimotor interaction, such as vocal learning and the use of feedback during speech ...
Louis Goldstein
doaj   +1 more source

Nonparametric Bayesian Double Articulation Analyzer for Direct Language Acquisition from Continuous Speech Signals

open access: yes, 2016
Human infants can discover words directly from unsegmented speech signals without any explicitly labeled data. In this paper, we develop a novel machine learning method called nonparametric Bayesian double articulation analyzer (NPB-DAA) that can ...
Nagasaka, Shogo   +2 more
core   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Using Modern Conducting Approaches in the Performance of Classical Repertoire

open access: yesStudia Universitatis Babeş-Bolyai. Musica
The study aims to reveal the conducting techniques as a complex unified system. Its components are profoundly interconnected and have inherent functions, content and significance.
Vasyl CHUCHMAN   +4 more
doaj   +1 more source

Learning weakly supervised multimodal phoneme embeddings

open access: yes, 2017
Recent works have explored deep architectures for learning multimodal speech representation (e.g. audio and images, articulation and audio) in a supervised way. Here we investigate the role of combining different speech modalities, i.e.
Chaabouni, Rahma   +3 more
core   +3 more sources

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

open access: yesMolecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli   +7 more
wiley   +1 more source

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