Artificial cells eavesdropping on HepG2 cells. [PDF]
Interface Focus, 2023 Cellular communication is a fundamental feature to ensure the survival of cellular assemblies, such as multicellular tissue, via coordinated adaption to changes in their surroundings. Consequently, the development of integrated semi-synthetic systems consisting of artificial cells (ACs) and mammalian cells requires feedback-based ...
Westensee IN, Städler B.
europepmc +5 more sources
Synthetic Cells Revisited: Artificial Cell Construction Using Polymeric Building Blocks [PDF]
Advanced Science, 2023 The exponential growth of research on artificial cells and organelles underscores their potential as tools to advance the understanding of fundamental biological processes.
Viviana Maffeis +4 more
doaj +3 more sources
Complex Coacervate Materials as Artificial Cells. [PDF]
Acc Mater Res, 2023 Cells have evolved to be self-sustaining compartmentalized systems that consist of many thousands of biomolecules and metabolites interacting in complex cycles and reaction networks. Numerous subtle intricacies of these self-assembled structures are still largely unknown.
Cook AB, Novosedlik S, van Hest JCM.
europepmc +5 more sources
Chemical Communication in Artificial Cells: Basic Concepts, Design and Challenges [PDF]
Frontiers in Molecular Biosciences, 2022 In the past decade, the focus of bottom-up synthetic biology has shifted from the design of complex artificial cell architectures to the design of interactions between artificial cells mediated by physical and chemical cues.
Hedi Karoui +3 more
doaj +3 more sources
Artificial cells drive neural differentiation. [PDF]
Sci Adv, 2020 Stimuli-responsive artificial cells synthesize and controllably release therapeutics for neural differentiation.
Toparlak ÖD +7 more
europepmc +8 more sources
Biomimetic behaviors in hydrogel artificial cells through embedded organelles. [PDF]
Proc Natl Acad Sci U S A, 2023 Significance Cellular form and functionality can be mimicked through entities known as artificial cells. One emerging chassis for artificial cells are hydrogel microparticles, which are gaining prominence due to their ability to replicate the gel-like ...
Allen ME +7 more
europepmc +2 more sources
Transmembrane signaling by a synthetic receptor in artificial cells. [PDF]
Nat Commun, 2023 Signal transduction across biological membranes is among the most important evolutionary achievements. Herein, for the design of artificial cells, we engineer fully synthetic receptors with the capacity of transmembrane signaling, using tools of ...
Søgaard AB +9 more
europepmc +2 more sources
Superparamagnetic Artificial Cells PLGA-Fe3O4 Micro/Nanocapsules for Cancer Targeted Delivery. [PDF]
Cancers (Basel), 2023 Simple Summary Cancer is the main cause of human death. Nanomedicine provides a new strategy for the treatment of diverse cancers. Among them, superparamagnetic artificial cell PLGA-Fe3O4 micro/nanocapsules demand great attention due to their excellent ...
Wang T, Chang TMS.
europepmc +2 more sources
DNA droplets for intelligent and dynamical artificial cells: from the viewpoint of computation and non-equilibrium systems. [PDF]
Interface Focus, 2023 Living systems are molecular assemblies whose dynamics are maintained by non-equilibrium chemical reactions. To date, artificial cells have been studied from such physical and chemical viewpoints.
Takinoue M.
europepmc +2 more sources
Reaction-Diffusion Patterning of DNA-Based Artificial Cells. [PDF]
J Am Chem Soc, 2022 Biological cells display complex internal architectures, with distinct micro environments that establish the chemical heterogeneity needed to sustain cellular functions.
Leathers A +7 more
europepmc +3 more sources