Results 91 to 100 of about 1,104,325 (338)

Formation of Polarized, Functional Artificial Cells from Compartmentalized Droplet Networks and Nanomaterials, Using One‐Step, Dual‐Material 3D‐Printed Microfluidics

open access: yesAdvanced Science, 2020
The bottom‐up construction of synthetic cells with user‐defined chemical organization holds considerable promise in the creation of bioinspired materials.
Jin Li   +6 more
doaj   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Recent Advancements in Targeted Delivery of Therapeutic Molecules in Neurodegenerative Disease–-Spinocerebellar Ataxia–-Opportunities and Challenges

open access: yesDrug Target Insights, 2008
Drug discovery and its methodologies have been very effective in terms of treating cancers and immunological disorders but have not been able to stop genetic diseases as most of the drugs target at the protein level.
Satya Prakash, Meenakshi Malhotra
doaj   +1 more source

In silico transitions to multicellularity

open access: yes, 2014
The emergence of multicellularity and developmental programs are among the major problems of evolutionary biology. Traditionally, research in this area has been based on the combination of data analysis and experimental work on one hand and theoretical ...
Duran-Nebreda, Salva, Solé, Ricard V.
core   +1 more source

Large Scale Ex Vivo Expansion of γδ T cells Using Artificial Antigen-presenting Cells

open access: green, 2022
Justin C. Boucher   +10 more
openalex   +2 more sources

Artificial Intelligence for Cell Segmentation, Event Detection, and Tracking for Label-Free Microscopy Imaging [PDF]

open access: gold, 2022
Lucia Maddalena   +4 more
openalex   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

open access: yesFEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini   +2 more
wiley   +1 more source

Dual-Function Au@Y2O3:Eu3+ Smart Film for Enhanced Power Conversion Efficiency and Long-Term Stability of Perovskite Solar Cells

open access: yesScientific Reports, 2017
In the present study, a dual-functional smart film combining the effects of wavelength conversion and amplification of the converted wave by the localized surface plasmon resonance has been investigated for a perovskite solar cell.
Chang Woo Kim   +6 more
doaj   +1 more source

Creation of Artificial Cell-Like Structures Promoted by Microfluidics Technologies

open access: yesMicromachines, 2019
The creation of artificial cells is an immensely challenging task in science. Artificial cells contribute to revealing the mechanisms of biological systems and deepening our understanding of them.
Yusuke Sato, Masahiro Takinoue
doaj   +1 more source

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