Results 51 to 60 of about 12,736,310 (369)

A Secretory Artificial Cell for Exocytosis [PDF]

Biophysical Journal, 2013
The complexity of exocytosis has left the molecular details of the process unclear. We present a minimal, artificial secretory cell designed for amperometric studies of release of signalling molecules through the fusion pore of single vesicles. In replacement of SNARE-proteins, the cell model has been equipped with an analog composed of complimentary ...
Fredrik Höök, Michael E. Kurczy, Raphaël Trouillon, Lisa Simonsson, Ann-Sofie Cans   +4 more
openaire   +2 more sources

Droplets: Unconventional Protocell Model with Life-Like Dynamics and Room to Grow

Life, 2014
Over the past few decades, several protocell models have been developed that mimic certain essential characteristics of living cells. These protocells tend to be highly reductionist simplifications of living cells with prominent bilayer membrane ...
Martin M Hanczyc
doaj   +1 more source

Bioinspired Molecular Factories with Architecture and In Vivo Functionalities as Cell Mimics

Advanced Science, 2020
Despite huge need in the medical domain and significant development efforts, artificial cells to date have limited composition and functionality. Although some artificial cells have proven successful for producing therapeutics or performing in vitro ...
Tomaž Einfalt, Martina Garni, Dominik Witzigmann, Sandro Sieber, Niklaus Baltisberger, Jörg Huwyler, Wolfgang Meier, Cornelia G. Palivan   +7 more
doaj   +1 more source

Artificial Cell Encapsulation for Biomaterials and Tissue Bio-Nanoengineering: History, Achievements, Limitations, and Future Work for Potential Clinical Applications and Transplantation

Journal of Functional Biomaterials, 2021
Pancreatic β-cell loss and failure with subsequent deficiency of insulin production is the hallmark of type 1 diabetes (T1D) and late-stage type 2 diabetes (T2D).
Armin Mooranian, Melissa Jones, Corina Mihaela Ionescu, Daniel Walker, Susbin Raj Wagle, Bozica Kovacevic, Jacqueline Chester, Thomas Foster, Edan Johnston, Jafri Kuthubutheen, Daniel Brown, Momir Mikov, Hani Al-Salami   +12 more
doaj   +1 more source

Information Fusion for Anomaly Detection with the Dendritic Cell Algorithm [PDF]

, 2010
Dendritic cells are antigen presenting cells that provide a vital link between the innate and adaptive immune system, providing the initial detection of pathogenic invaders.
Aickelin, Uwe, Greensmith, Julie, Tedesco, Gianni   +2 more
core   +3 more sources

Suppression of Tumorigenesis: Modulation of Inflammatory Cytokines by Oral Administration of Microencapsulated Probiotic Yogurt Formulation

International Journal of Inflammation, 2010
The objective of this study was to examine the ability of a novel microencapsulated probiotic yogurt formulation to suppress the intestinal inflammation.
Aleksandra Malgorzata Urbanska, Arghya Paul, Jasmine Bhahena, Satya Prakash   +3 more
doaj   +1 more source

Cell-sized confinement controls generation and stability of a protein wave for spatiotemporal regulation in cells

eLife, 2019
The Min system, a system that determines the bacterial cell division plane, uses changes in the localization of proteins (a Min wave) that emerges by reaction-diffusion coupling.
Shunshi Kohyama, Natsuhiko Yoshinaga, Miho Yanagisawa, Kei Fujiwara, Nobuhide Doi   +4 more
doaj   +1 more source

Intercellular communication between artificial cells by allosteric amplification of a molecular signal

Nature Communications, 2020
Multicellular organisms rely on intercellular communication to coordinate the behaviour of individual cells, which enables their differentiation and hierarchical organization.
Bastiaan C Buddingh', Janneke Elzinga, J. V. van Hest   +2 more
semanticscholar   +1 more source

Nanobiotechnological Nanocapsules Containing Polyhemoglobin-Tyrosinase: Effects on Murine B16F10 Melanoma Cell Proliferation and Attachment

Journal of Skin Cancer, 2012
We have reported previously that daily intravenous infusions of a soluble nanobiotechnological complex, polyhemoglobin-tyrosinase [polyHb-Tyr], can suppress the growth of murine B16F10 melanoma in a mouse model.
Yun Wang, Thomas M. S. Chang
doaj   +1 more source

Intrasplenic Transplantation of Bioencapsulated Mesenchymal Stem Cells Improves the Recovery Rates of 90% Partial Hepatectomized Rats

Stem Cells International, 2012
Mesenchymal stem cells (MSCs) derived from bone marrow can secrete cytokines and growth factors and can transdifferentiate into liver cells. We transplanted polymeric membrane bioencapsulated MSCs into the spleens of 90% partial hepatectomized rats. This
Zun Chang Liu, Thomas Ming Swi Chang
doaj   +1 more source