Results 51 to 60 of about 108,274 (257)

A Toolkit for Targeted Neuromodulation of Striatal Direct Pathway Neurons Rescues Parkinsonian Motor Deficits in Mice

Advanced Science, EarlyView.
An adeno‐associated virus (AAV) toolkit enables selective anatomical and functional targeting of striatal D1‐MSNs through retrograde transduction. Enhanced capsids and engineered enhancers drive robust transgene expression across murine and primate models.
Zexuan Hong, Yujing Zhang, Junjiao Zhang, Hanhe Liu, Qiwei Liu, Yanglei Li, Lixin Yang, Lixia Li, Zhongjie Liu, Zhen Yuan, Zhonghua Lu, Yefei Chen, Yuantao Li, Yuwu Jiang, Taian Liu   +14 more
wiley   +1 more source

Two Routes to Land: Genomic Underpinnings of Parallel Aerial Egg Deposition in Aquatic Old‐World Pila and New‐World Pomacea (Ampullariidae)

Advanced Science, EarlyView.
Comparative genomics of Gondwana‐diverged Pila and Pomacea reveals parallel evolution of aerial oviposition. Convergent chromosomal rearrangements reshape regulatory landscapes within topologically associating domains. Lineage‐specific gene family expansions and viral‐derived perivitelline proteins (PV1) underpin desiccation resistance.
Yufei Zhou, Huawei Mu, Xueying Nie, Yue Gao, Hui Wang, Ling Fang, Tiangang Luan, Monthon Ganmanee, Jian‐Wen Qiu, Jin Sun, Jack Chi‐Ho Ip   +10 more
wiley   +1 more source

Biological Evaluation of Spodoptera Frugiperda (Lepidoptera: Noctuidae) Reared on Various Artificial Diets Compared to the Main Host [PDF]

Journal of Plant Protection and Pathology
Spodoptera frugiperda is a destructive lepidopteran pest that seriously affects many crops. To obtain experimental individuals for use in IPM experiments., it is crucial to improve the rearing technique for S. frugiperda.
Suzan Badr, Suzan Ali, Neven Faiz
doaj   +1 more source

Silkworm Pupae Function as Efficient Producers of Recombinant Glycoproteins with Stable-Isotope Labeling

Biomolecules, 2020
Baculovirus-infected silkworms are promising bioreactors for producing recombinant glycoproteins, including antibodies. Previously, we developed a method for isotope labeling of glycoproteins for nuclear magnetic resonance (NMR) studies using silkworm ...
Hirokazu Yagi, Saeko Yanaka, Rina Yogo, Akari Ikeda, Masayoshi Onitsuka, Toshio Yamazaki, Tatsuya Kato, Enoch Y. Park, Jun Yokoyama, Koichi Kato   +9 more
doaj   +1 more source

VDAC1 Upregulation Induces Hyperexcitability of Nociceptive Sensory Neurons Via Enhanced Mitochondrial Atp Efflux in Neuropathic Pain

Advanced Science, EarlyView.
The mechanism diagram of VDAC1 mediating neuronal excitability and neuropathic pain. Briefly, VDAC1 is expressed in DRG neurons and is upregulated following CCI‐induced neuropathic pain. This upregulation enhances ATP transport from mitochondria to the cytoplasm in sensory neurons, leading to increased neuronal excitability and pain behavior.
Fengrun Sun, Ning Yu, Liang Yu, Xiaofen Tian, Yujia Ma, Yikuan Xie, Tao Wang, Chao Ma   +7 more
wiley   +1 more source

Multidimensional and Multifunctional Laser‐Induced Graphene (LIG) for Point‐of‐Care and Wearable Biosensing, Theranostics, and Bioactive Interfaces Toward Personalized Healthcare and Regenerative Medicine

Advanced Science, EarlyView.
Multidimensional laser‐induced graphene (LIG) spanning from 0D to 3D architectures is comprehensively reviewed for multifunctional biomedical platforms, including biosensing, theranostics, and bioactive interface applications, which highlights its potentials for point‐of‐care diagnostics, wearable health monitoring, smart drug delivery, and tissue ...
Li Zhang, Yurou Yuan, Xiaohong Ding, Wing Cheung Mak   +3 more
wiley   +1 more source

A Single‐Cell Transcriptomic Atlas of the Ovine Rumen Microbiome Characterizes Lineage‐Specific Metabolic Shifts Associated with Host Heat Tolerance

Advanced Science, EarlyView.
An optimized single‐cell transcriptomic framework profiles over 60 000 cells to map the ovine rumen microbiome, partitioning the ecosystem into seven cross‐species functional clusters. In heat‐resistant hosts, a lineage‐specific metabolic shift in Anaerovibrio lipolyticus toward a highly glycolytic phenotype contributes to a “nutritional sparing ...
Sanbao Zhang, Qinyang Jiang, Junjie Ma, Jianwei Zou, Fan Wang, Feifei Lv, Yanna Huang, Yongcheng Wang, Ziye Xu   +8 more
wiley   +1 more source

Survival and Metabolic Enzyme Response of Spodoptera exigua Larvae Under Different Nutritional Conditions

Agronomy
Spodoptera exigua has emerged as a globally agricultural pest due to its strong adaptability to diverse nutritional conditions. In this study, we used artificial diets with a protein-to-carbohydrate (P:C) ratio of 1:1 as the control and examined the ...
Hongzhi Zhang, Xin Gao, Fengjiao Qiao, Ziyu Shao, Yan Shi, Bin Zhang, Chuande Zhao   +6 more
doaj   +1 more source

Consumo e utilização de alimento por Spodoptera frugiperda (J. E. Smith, 1797) (Lepidoptera: Noctuidae) em duas temperaturas Consumption and utilization of food by Spodoptera frugiperda (J. E. Smith, 1797) (Lepidoptera: Noctuidae) at two different temperatures

Ciência e Agrotecnologia, 2004
Conduziu-se este trabalho com o objetivo de determinar, mediante medidas de consumo e utilização de alimento, a temperatura mais adequada para a criação de Spodoptera frugiperda (J. E. SMITH, 1797) em dieta artificial.
Gustavo Rossato Busato, Anderson Dionei Grützmacher, Mauro Silveira Garcia, Fabrizio Pinheiro Giolo, Sandro Daniel Nörnberg   +4 more
doaj   +1 more source

Microbial Flora of Artificial Fish Diets

Fish Pathology, 1976
Twenty different fish diets marketed in Japan were examined for the microbial flora.The total counts of aerobic bacteria determined at 30°C ranged from 1.8×103 to 8.0×105 pergram of diet with a mean value of 1.4×105. The microflora of these diets were consisted mainly of Gram-positive bacteria, and the most predominant organisms belong to the genus ...
KITAO, Tadatoshi, AOKI, Takashi
openaire   +2 more sources