Results 31 to 40 of about 192,160 (247)

Natural Variation and Neuromechanical Systems [PDF]

open access: yes, 2009
Natural variation plays an important but subtle and often ignored role in neuromechanical systems. This is especially important when designing for living or hybrid systems \ud which involve a biological or self-assembling component.
Alicea, Bradly
core   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

open access: yesFEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer   +7 more
wiley   +1 more source

Stiffness and position control of a prosthetic wrist by means of an EMG interface [PDF]

open access: yes, 2010
In this paper, we present a novel approach for decoding electromyographic signals from an amputee and for interfacing them with a prosthetic wrist. The model for the interface makes use of electromyographic signals from electrodes placed in agonistic and
Carloni, Raffaella   +2 more
core   +2 more sources

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Bioinspired Nanomaterials: Self Stiffening Artificial Muscles [PDF]

open access: yes, 2014
Cytoskeletal organization and elasticity are greatly influenced by molecular stiffness and sterics as well as externally imposed and internally generated stresses or so it might be hypothesized.
Patra, Prabir
core  

Freeform Fabrication of Ionomeric Polymer-Metal Composite Actuators [PDF]

open access: yes, 2005
Ionomeric polymer-metal composite (IPMC) actuators are a type of soft electromechanically active material which offers large displacement, rapid motion with only ~1V stimulus.
Lipson, Hod, Malone, Evan
core   +3 more sources

Polymer artificial muscles

open access: yesMaterials Today, 2007
The various types of natural muscle are incredible material systems that enable the production of large deformations by repetitive molecular motions. Polymer artificial muscle technologies are being developed that produce similar strains and higher stresses using electrostatic forces, electrostriction, ion insertion, and molecular conformational ...
Mirfakhrai, Tissaphern   +2 more
openaire   +1 more source

Substrate Stress Relaxation Regulates Cell‐Mediated Assembly of Extracellular Matrix

open access: yesAdvanced Functional Materials, EarlyView.
Silicone‐based viscoelastic substrates with tunable stress relaxation reveal how matrix mechanics regulates cellular mechanosensing and cell‐mediated matrix remodelling in the stiff regime. High stress relaxation promotes assembly of fibronectin fibril‐like structures, increased nuclear localization of YAP and formation of β1 integrin‐enriched ...
Jonah L. Voigt   +2 more
wiley   +1 more source

Asimov's Coming Back [PDF]

open access: yes, 2006
Ever since the word ‘ROBOT’ first appeared in a science\ud fiction in 1921, scientists and engineers have been trying\ud different ways to create it. Present technologies in\ud mechanical and electrical engineering makes it possible\ud to have robots in ...
Wang, Mr. L.
core  

Negative Linear Compressibility

open access: yes, 2015
While all materials reduce their intrinsic volume under hydrostatic (uniform) compression, a select few actually \emph{expand} along one or more directions during this process of densification.
Cairns, Andrew B., Goodwin, Andrew L.
core   +1 more source

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