Results 1 to 10 of about 79,804 (165)

Ionophore application for artificial oocyte activation and its potential effect on morphokinetics: a sibling oocyte study. [PDF]

J Assist Reprod Genet, 2021
To evaluate whether ionophore application at the oocyte stage changes the morphokinetics of the associated embryos in cases of artificial oocyte activation.
Shebl O, Trautner PS, Enengl S, Reiter E, Allerstorfer C, Rechberger T, Oppelt P, Ebner T.   +7 more
europepmc   +6 more sources

Artificial oocyte activation using Ca²⁺ ionophores following intracytoplasmic sperm injection for low fertilization rate. [PDF]

Front Endocrinol (Lausanne), 2023
This large multi-center retrospective study examined whether artificial oocyte activation (AOA) using Ca2+ ionophore following ICSI improves the live birth rate for couples with previous ICSI cycles of unexplained low fertilization rate.
Akashi K, Yamada M, Jwa SC, Utsuno H, Kamijo S, Hirota Y, Tanaka M, Osuga Y, Kuji N.   +8 more
europepmc   +5 more sources

Live birth following an innovative artificial oocyte activation protocol using double calcium stimulators. [PDF]

Chin Med J (Engl), 2023
Intracytoplasmic sperm injection (ICSI) is an effective method for human-assisted reproductive technology, especially for male-factor infertility. However, the average fertilization rate of ICSI is 70%, and total fertilization failure occurs in 3% of ...
Gao Y, Yang D, Fang Y, Wang X, Li D.
europepmc   +5 more sources

Artificial oocyte activation with Ca²⁺ ionophore improves reproductive outcomes in patients with fertilization failure and poor embryo development in previous ICSI cycles. [PDF]

Front Endocrinol (Lausanne), 2023
Research question Does artificial oocyte activation (AOA) by a calcium ionophore (ionomycin) improve the previous fertilization failure or poor embryo development of intracytoplasmic sperm injection (ICSI) account for male factor infertility or other ...
Ruan JL, Liang SS, Pan JP, Chen ZQ, Teng XM.   +4 more
europepmc   +2 more sources

Efficacy of Artificial Oocyte Activation in Improving the Reproductive Outcome in Poor Responders: A Single Centre Cohort Study. [PDF]

J Family Reprod Health, 2023
Objective: Achieving pregnancy in poor ovarian response patients is a challenge. Failed fertilization after ICSI, despite normal semen parameters is due to defects in oocyte activation.
Kaur B, Malik S, Prakash V, Bhatia V, Gupta D.   +4 more
europepmc   +2 more sources

Embryo development and live birth resulted from artificial oocyte activation after microdissection testicular sperm extraction with ICSI in patients with non-obstructive azoospermia. [PDF]

Front Endocrinol (Lausanne), 2023
Introduction The application of microdissection testicular sperm extraction (micro-TESE) to retrieve the sperm of patients with non-obstructive azoospermia (NOA) has greatly increased. Patients with NOA often have poor quality sperm. Unfortunately, there
Zhang X, Li L, Zhang W, Luo Y, Mao Y, Du H, Li L.   +6 more
europepmc   +2 more sources

Artificial oocyte activation may improve embryo quality in older patients with diminished ovarian reserve undergoing IVF-ICSI cycles. [PDF]

J Ovarian Res, 2022
Background Artificial oocyte activation (AOA) is used to improve fertilization rate following fertilization failure after intracytoplasmic sperm injection (ICSI). Several studies have also shown that AOA may be involved in embryo development.
Tsai TE, Lin PH, Lian PF, Li CJ, Vitale SG, Mikuš M, Su WP, Tsai HW, Tsui KH, Lin LT.   +9 more
europepmc   +2 more sources

DNA methylation and gene expression changes in mouse pre- and post-implantation embryos generated by intracytoplasmic sperm injection with artificial oocyte activation. [PDF]

Reprod Biol Endocrinol, 2021
Background The application of artificial oocyte activation (AOA) after intracytoplasmic sperm injection (ICSI) is successful in mitigating fertilization failure problems in assisted reproductive technology (ART).
Yin M, Yu W, Li W, Zhu Q, Long H, Kong P, Lyu Q.   +6 more
europepmc   +2 more sources

Neurodevelopmental status of children aged 12 to 60 months conceived with artificial oocyte activation in a Cross-Sectional study. [PDF]

Sci Rep
The potential effect of artificial oocyte activation (AOA) following intracytoplasmic sperm injection (ICSI) on neurodevelopment remains uncertain.
Miyazaki K, Yamada M, Akashi K, Jwa SC, Utsuno H, Kamijo S, Arimitsu T, Hida M, Sato Y, Hirota Y, Narumi S, Tanaka M, Osuga Y, Kuji N.   +13 more
europepmc   +2 more sources

The Effect of Artificial Oocyte Activation on Blastocyst Development in Patients With Low Blastocyst Rates: A Retrospective Cohort Study. [PDF]

Cureus
Introduction and aim: Physiological oocyte activation requires a synergy between the oocyte and sperm to release calcium (Ca2+) through oscillations. The absence of such synergy between the oocyte and sperm leads to a negative impact on oocyte activation.
Sendy F, Hemmings R, Kadoch IJ, Jamal W, Phillips S.   +4 more
europepmc   +2 more sources