Results 21 to 30 of about 7,063 (180)

Artificial oocyte activation: evidence for clinical readiness [PDF]

Reproductive BioMedicine Online, 2016
Artificial oocyte activation using Ca(2+)ionophores or similar compounds is a widely applied technique in IVF laboratories. This is all the more interesting as most of the agents aiming for intracellular Ca(2+) increase do not result in physiological Ca(2+) oscillations but much rather cause a single Ca(2+) transient.
Ebner, T., Montag, M.
openaire   +2 more sources

Artificial oocyte activation: physiological, pathophysiological and ethical aspects [PDF]

Systems Biology in Reproductive Medicine, 2018
Infertile couples with low oocyte yield in combination with abnormal semen parameters may experience intra-cytoplasmic sperm injection (ICSI) failure. An established factor associated with ICSI failure is oocyte activation deficiency (AOD). The latter originates from seminal contributors, such as phospholipase C-zeta (PLCζ) that is not adequate to ...
Anifandis, G., Michopoulos, A., Daponte, A., Chatzimeletiou, K., Simopoulou, M., Messini, C.I., Polyzos, N.P., Vassiou, K., Dafopoulos, K., Goulis, D.G.   +9 more
openaire   +3 more sources

In vitro Activation of mouse oocytes through intracellular Ca2+ regulation

Journal of Human Reproductive Sciences, 2020
Background: Ca2+ signaling pathway is suggested to play an essential role in mediating oocyte maturation. Aims: The aim of this study was to evaluate intracellular Ca2+ of resistant immature oocytes that failed to resume meiosis following subsequent in ...
Nining Handayani, Budi Wiweko, Sarah Chairani Zakirah, Arief Boediono   +3 more
doaj   +1 more source

Sperm-oocyte interplay: an overview of spermatozoon’s role in oocyte activation and current perspectives in diagnosis and fertility treatment

Cell & Bioscience, 2021
The fertilizing spermatozoon is a highly specialized cell that selects from millions along the female tract until the oocyte. The paternal components influence the oocyte activation during fertilization and are fundamental for normal embryo development ...
Mohammad Ishraq Zafar, Shi Lu, Honggang Li   +2 more
doaj   +1 more source

Homozygous Loss of Septin12, but not its Haploinsufficiency, Leads to Male Infertility and Fertilization Failure

Frontiers in Cell and Developmental Biology, 2022
The SEPTIN12 gene has been associated with male infertility. Male Septin12+/− chimera mice were infertile, supporting the prevailing view that SEPTIN12 haploinsufficiency causes male infertility.
Haixia Chen, Peng Li, Xiaoling Du, Yiding Zhao, Lingling Wang, Ye Tian, Xueru Song, Ling Shuai, Xiaohong Bai, Lingyi Chen   +9 more
doaj   +1 more source

Artificial Activation of Oocytes from Sinclair Miniature Pigs [PDF]

Journal of Applied Animal Research, 1996
Abstract Prather, R.S., Gibson, J. and Parry, T.W. 1996. Artificial activation of oocytes from Sinclair miniature pigs. J. Appl. Anim. Res., 10: 125–134. The experiments reported in this paper are designed to evaluate in Sinclair miniature pig oocytes a number of stimuli that are known to result in activation of domestic pig and mouse oocytes.
R. S. Prather, J. Gibson, T. W. Parry
openaire   +1 more source

Mechanical Egg Activation and Rearing of First Instar Larvae of Sirex noctilio (Hymenoptera: Siricidae)

Insects, 2023
Egg activation is a cellular transition of an arrested mature oocyte into a developing embryo through a coordinated series of events. Previous studies in Hymenoptera have indicated that mechanical pressure can induce egg activation.
Elmarie van der Merwe, Bernard Slippers, Gudrun Dittrich-Schröder   +2 more
doaj   +1 more source

The role of nitric oxide in parthenogenetic activation of pig oocytes: A review

Czech Journal of Animal Science, 2007
Parthenogenetic activation of mammalian oocytes with artificial stimuli is commonly applied in various reproductive biotechniques, e.g. cloning using nuclear transfer. For this reason, many studies focus on oocyte activation in vitro.
J. Petr, E. Chmelíková, L. Tůmová, M. Ješeta   +3 more
doaj   +1 more source

The present status of artificial oocyte activation in assisted reproductive technology

Reproductive Medicine and Biology, 2008
Intracytoplasmic sperm injection (ICSI) is the most effective treatment for achieving fertilization in assisted reproductive technology (ART). However, fertilization failure occurs. The incidence of fertilization failure after ICSI is 1–5%. Approximately 50% of fertilization failure cases could be attributed to the abnormality of sperm factor.
Kaoru, Yanagida, Yoko, Fujikura, Haruo, Katayose   +2 more
openaire   +2 more sources

TRPV3 Channels Mediate Strontium-Induced Mouse-Egg Activation

Cell Reports, 2013
In mammals, calcium influx is required for oocyte maturation and egg activation. The molecular identities of the calcium-permeant channels that underlie the initiation of embryonic development are not established.
Ingrid Carvacho, Hoi Chang Lee, Rafael A. Fissore, David E. Clapham   +3 more
doaj   +1 more source