Results 11 to 20 of about 17,633 (227)

Ionophore application for artificial oocyte activation and its potential effect on morphokinetics: a sibling oocyte study. [PDF]

J Assist Reprod Genet, 2021
Abstract Purpose To evaluate whether ionophore application at the oocyte stage changes the morphokinetics of the associated embryos in cases of artificial oocyte activation. Methods In a prospective sibling oocyte approach, 78 ICSI patients with suspected fertilization ...
Shebl O, Trautner PS, Enengl S, Reiter E, Allerstorfer C, Rechberger T, Oppelt P, Ebner T.   +7 more
europepmc   +6 more sources

Functional Roles of Src Kinase Activity in Oocyte Maturation and Artificial Egg Activation in Xenopus laevis [PDF]

Cells
Src family tyrosine kinases regulate oocyte maturation and fertilization in many species, yet their physiological roles in Xenopus laevis (X. laevis) remain incompletely defined. Here, we generated three X. laevis Src (xSrc) constructs with defined point
Ken-ichi Sato, Alexander A. Tokmakov
doaj   +2 more sources

Rescuing Fertilization Failure in ICSI: A Narrative Review of Calcium Ionophore Activation, PLCζ Testing, and Embryo Morphokinetics [PDF]

Biomedicines
Fertilisation failure following intracytoplasmic sperm injection (ICSI) is a significant challenge in assisted reproductive technology (ART), particularly in the absence of an identifiable cause. Artificial oocyte activation (AOA), typically with calcium
Charalampos Voros, Despoina Mavrogianni, Diamantis Athanasiou, Ioakeim Sapantzoglou, Kyriakos Bananis, Antonia Athanasiou, Aikaterini Athanasiou, Georgios Papadimas, Charalampos Tsimpoukelis, Ioannis Papapanagiotou, Dimitrios Vaitsis, Aristotelis-Marios Koulakmanidis, Maria Anastasia Daskalaki, Vasileios Topalis, Nikolaos Thomakos, Marianna Theodora, Panagiotis Antsaklis, Fotios Chatzinikolaou, Dimitrios Loutradis, Georgios Daskalakis   +19 more
doaj   +2 more sources

Assisted Oocyte Activation following Intracytoplasmic Sperm Injection: A Sensible Option for Infertile Couples with Severe Teratozoospermia [PDF]

International Journal of Fertility and Sterility, 2023
The intracytoplasmic sperm injection (ICSI) has significantly improved male factor infertility treatment; however, complete fertilization failure still occurs in 1-5% of ICSI treatment cycles mainly due to oocyte activation failure.
Marziyeh Tavalaee, Nushin Naderi, Navid Esfandiari, Mohammad Hossein Nasr-Esfahani   +3 more
doaj   +1 more source

Preimplantation Developmental Competence of Bovine and Porcine Oocytes Activated by Zinc Chelation

Animals, 2022
After sperm-oocyte fusion, intracytoplasmic rises of calcium (Ca) induce the release of zinc (Zn) out of the oocyte (Zn sparks). Both phenomena are known to play an essential role in the oocyte activation process.
Juan P. Cabeza, Juan Cámera, Olinda Briski, Minerva Yauri Felipe, Daniel F. Salamone, Andrés Gambini   +5 more
doaj   +1 more source

Artificial oocyte activation: evidence for clinical readiness [PDF]

Reproductive BioMedicine Online, 2016
Artificial oocyte activation using Ca(2+)ionophores or similar compounds is a widely applied technique in IVF laboratories. This is all the more interesting as most of the agents aiming for intracellular Ca(2+) increase do not result in physiological Ca(2+) oscillations but much rather cause a single Ca(2+) transient.
Ebner, T., Montag, M.
openaire   +2 more sources

Artificial oocyte activation: physiological, pathophysiological and ethical aspects [PDF]

Systems Biology in Reproductive Medicine, 2018
Infertile couples with low oocyte yield in combination with abnormal semen parameters may experience intra-cytoplasmic sperm injection (ICSI) failure. An established factor associated with ICSI failure is oocyte activation deficiency (AOD). The latter originates from seminal contributors, such as phospholipase C-zeta (PLCζ) that is not adequate to ...
Anifandis, G., Michopoulos, A., Daponte, A., Chatzimeletiou, K., Simopoulou, M., Messini, C.I., Polyzos, N.P., Vassiou, K., Dafopoulos, K., Goulis, D.G.   +9 more
openaire   +3 more sources

Effects of assisted oocyte activation with calcium- ionophore and strontium chloride on in vitro ICSI outcomes [PDF]

Iranian Journal of Basic Medical Sciences, 2018
Objective(s): Failed fertilization after intra-cytoplasmic sperm injection (ICSI) is mainly attributed to failed oocyte activation and can be overcome by artificial oocyte activation (AOA).
Marziyeh Norozi-Hafshejani, Marziyeh Tavalaee, Leila Azadi, Mehrnoosh Bahadorani, Mohamad Hosein Nasr Esfahani   +4 more
doaj   +1 more source

Failed Fertilization in ART: What are the Causes and Methods to Improve Fertilization

Fertility & Reproduction, 2023
Introduction of clinical ICSI made a revolution in achieving higher fertilization in ART programs. However, ICSI does not completely eliminate the risk of fertilization failure as total fertilization failure (TFF) occurs in 1-3% of ICSI cycles. TFF leads
Satish Kumar Adiga
doaj   +1 more source

Comparison of Human Oocyte Activation Between Round-Headed Sperm Injection Followed by Calcium Ionophore Treatment and Normal Sperm Injection in a Patient With Globozoospermia

Frontiers in Endocrinology, 2020
Fertilization failure is common in patients with round-headed sperm, a form of globozoospermia. Artificial oocyte activation is able to assist oocyte fertilization after sperm injection in these patients.
Xiangli Niu, Qiuyan Ruan, Craig A. Witz, Weihua Wang   +3 more
doaj   +1 more source