Results 11 to 20 of about 79,942 (242)

Chloroquine inhibits artificial oocyte activation induced by ethanol or Sr²⁺ but not by sperm in mice. [PDF]

J Reprod Dev
Calcium release from the endoplasmic reticulum via sperm-derived phospholipase C zeta is crucial for oocyte activation during fertilization. Chloroquine (CQ) inhibits the increase in cytoplasmic calcium.
Yamazaki T, Bari MW, Kishigami S.
europepmc   +4 more sources

Artificial oocyte activation with calcium ionophore for frozen sperm cycles [PDF]

Systems Biology in Reproductive Medicine, 2018
Fertilization problems are the major problems that may be faced in 30-55% of the patients during an intracytoplasmic sperm injection (ICSI) cycle. A successful oocyte activation depends on factors related to both sperm and oocyte, and one of the important factors that mediates the process is Ca2+ concentration within the oocyte.
S. Karabulut, Ö. Aksünger, Can Ata, Yusuf Sağıroglu, Ilknur Keskin   +4 more
semanticscholar   +6 more sources

Artificial oocyte activation improves ICSI outcomes following unexplained fertilization abnormalities.

Reproductive BioMedicine Online
RESEARCH QUESTION Is artificial oocyte activation (AOA) effective for patients with unexplained low or no fertilization following IVF/intracytoplasmic sperm injection (ICSI)?
C. Nicholson, M. Dean, A. Attia, P. A. Milne, S. D. da Silva   +4 more
semanticscholar   +6 more sources

The efficacy of ionomycin - induced artificial oocyte activation in preventing fertilization failure in an ICSI cycle: an eight - year retrospective study. [PDF]

J Ovarian Res
Artificial oocyte activation (AOA) procedure may prevent the occurrence of fertilization failure following ICSI; however, the specific efficacy of AOA remains controversial.
Li M, Zhang N, Sun Y, Huang J, Li Q, Li J, Liu P, Li R.   +7 more
europepmc   +2 more sources

Risk of birth defects in children conceived by artificial oocyte activation and intracytoplasmic sperm injection: a meta-analysis. [PDF]

Reprod Biol Endocrinol, 2020
Background Whether artificial oocyte activation (ICSI-AOA) will increase the risk of birth defects remains controversial. Thus, we performed this study to evaluate the risk of birth defects and further compare the incidence of different birth defects ...
Long R, Wang M, Yang QY, Hu SQ, Zhu LX, Jin L.   +5 more
europepmc   +2 more sources

Artificial oocyte activation: physiological, pathophysiological and ethical aspects [PDF]

Systems Biology in Reproductive Medicine, 2018
Infertile couples with low oocyte yield in combination with abnormal semen parameters may experience intra-cytoplasmic sperm injection (ICSI) failure. An established factor associated with ICSI failure is oocyte activation deficiency (AOD).
G. Anifandis, Alexandros Michopoulos, A. Daponte, K. Chatzimeletiou, M. Simopoulou, C. Messini, N. P. Polyzos, K. Vassiou, K. Dafopoulos, D. Goulis   +9 more
semanticscholar   +4 more sources

Use of phospholipase C zeta analysis to identify candidates for artificial oocyte activation: a case series of clinical pregnancies and a proposed algorithm for patient management.

Fertility and Sterility, 2020
OBJECTIVE To investigate the applicability of phospholipase C zeta (PLCζ) analysis in assisting the clinical decision-making process when considering artificial oocyte activation (AOA) for infertile males in assisted reproductive technology.
Xin Meng, Pedro Melo, Céline Jones, C. Ross, G. Mounce, K. Turner, T. Child, K. Coward   +7 more
semanticscholar   +3 more sources

Assessing the impact of calcium ionophore on pregnancy outcomes in artificial oocyte activation cycles: a 10-year update of systematic review and meta-analysis. [PDF]

J Assist Reprod Genet
Zhang J, Sui Y, Xiao M, Sun X, Fu J.
europepmc   +2 more sources

ARTIFICIAL OOCYTE ACTIVATION WITH CALCIUM IONOPHORE; IS IT SAFE? [PDF]

Fertility and Sterility, 2021
I. Chabchoub, S. Mnallah, med Habib BEN Aribia, K. Mahmoud, M. Khrouf, F. Zhioua, K. Terras, H. Elloumi   +7 more
semanticscholar   +2 more sources

Phospholipase C zeta and oocyte activation defects: moving toward the objective identification of patients eligible for artificial oocyte activation. [PDF]

Fertility and Sterility, 2020
R. Figueira, S. Esteves
semanticscholar   +3 more sources