Results 21 to 30 of about 79,942 (242)

Assisted Oocyte Activation following Intracytoplasmic Sperm Injection: A Sensible Option for Infertile Couples with Severe Teratozoospermia [PDF]

International Journal of Fertility and Sterility, 2023
The intracytoplasmic sperm injection (ICSI) has significantly improved male factor infertility treatment; however, complete fertilization failure still occurs in 1-5% of ICSI treatment cycles mainly due to oocyte activation failure.
Marziyeh Tavalaee, Nushin Naderi, Navid Esfandiari, Mohammad Hossein Nasr-Esfahani   +3 more
doaj   +1 more source

Characterization and therapy of fertilization failure in murine and human models with HNRNPR mutations. [PDF]

EMBO Mol Med
Oocyte activation is essential for successful fertilization and subsequent embryonic development. However, only a few disease-causing genes have been associated with sperm-derived oocyte activation failure, and the underlying molecular mechanisms and ...
Gan S, Gan S, Li Y, Yin L, Yang X, Lou C, Li S, Lin M, Li X, Xu W, Zhou J, Hu P, Yao Z, Yuan Y, Sheng J, Zhang C, Yang W, Li Y, Huang H.   +18 more
europepmc   +2 more sources

Effect of Epidermal Growth Factor and 6-Dimethylaminopurine on In Vitro Maturation and Artificial Activation of Spix's Yellow-Toothed Cavy (<i>Galea spixii</i> Wagler, 1831) Oocytes. [PDF]

Animals (Basel)
The successful application of assisted reproductive technologies (ARTs), such as in vitro maturation (IVM) and artificial oocyte activation, requires species-specific adaptations. Although these methods are routinely used in laboratory rodents, their use
Aquino LVC, Olindo SL, Silva YLF, Silva VD, Oliveira LRM, Oliveira MF, Pereira AF.   +6 more
europepmc   +2 more sources

Preimplantation Developmental Competence of Bovine and Porcine Oocytes Activated by Zinc Chelation

Animals, 2022
After sperm-oocyte fusion, intracytoplasmic rises of calcium (Ca) induce the release of zinc (Zn) out of the oocyte (Zn sparks). Both phenomena are known to play an essential role in the oocyte activation process.
Juan P. Cabeza, Juan Cámera, Olinda Briski, Minerva Yauri Felipe, Daniel F. Salamone, Andrés Gambini   +5 more
doaj   +1 more source

Artificial oocyte activation: evidence for clinical readiness [PDF]

Reproductive BioMedicine Online, 2016
Artificial oocyte activation using Ca(2+)ionophores or similar compounds is a widely applied technique in IVF laboratories. This is all the more interesting as most of the agents aiming for intracellular Ca(2+) increase do not result in physiological Ca(2+) oscillations but much rather cause a single Ca(2+) transient.
Ebner, T., Montag, M.
openaire   +2 more sources

Effects of assisted oocyte activation with calcium- ionophore and strontium chloride on in vitro ICSI outcomes [PDF]

Iranian Journal of Basic Medical Sciences, 2018
Objective(s): Failed fertilization after intra-cytoplasmic sperm injection (ICSI) is mainly attributed to failed oocyte activation and can be overcome by artificial oocyte activation (AOA).
Marziyeh Norozi-Hafshejani, Marziyeh Tavalaee, Leila Azadi, Mehrnoosh Bahadorani, Mohamad Hosein Nasr Esfahani   +4 more
doaj   +1 more source

Failed Fertilization in ART: What are the Causes and Methods to Improve Fertilization

Fertility & Reproduction, 2023
Introduction of clinical ICSI made a revolution in achieving higher fertilization in ART programs. However, ICSI does not completely eliminate the risk of fertilization failure as total fertilization failure (TFF) occurs in 1-3% of ICSI cycles. TFF leads
Satish Kumar Adiga
doaj   +1 more source

Comparison of Human Oocyte Activation Between Round-Headed Sperm Injection Followed by Calcium Ionophore Treatment and Normal Sperm Injection in a Patient With Globozoospermia

Frontiers in Endocrinology, 2020
Fertilization failure is common in patients with round-headed sperm, a form of globozoospermia. Artificial oocyte activation is able to assist oocyte fertilization after sperm injection in these patients.
Xiangli Niu, Qiuyan Ruan, Craig A. Witz, Weihua Wang   +3 more
doaj   +1 more source

Artificial Activation of Oocytes from Sinclair Miniature Pigs [PDF]

Journal of Applied Animal Research, 1996
Abstract Prather, R.S., Gibson, J. and Parry, T.W. 1996. Artificial activation of oocytes from Sinclair miniature pigs. J. Appl. Anim. Res., 10: 125–134. The experiments reported in this paper are designed to evaluate in Sinclair miniature pig oocytes a number of stimuli that are known to result in activation of domestic pig and mouse oocytes.
R. S. Prather, J. Gibson, T. W. Parry
openaire   +1 more source

Cryopreservation of equine oocytes: looking into the crystal ball [PDF]

, 2020
In vitro embryo production has evolved rapidly in the horse over the past decade, but blastocyst rates from vitrified equine oocytes remain quite poor and further research is needed to warrant application.
Angel Velez, Daniel, De Coster, Tine, Smits, Katrien, Van Soom, Ann, Woelders, Henri   +4 more
core   +2 more sources