Results 131 to 140 of about 33,160 (231)

Intratumoral Microbiota in Tumor: Current Understandings and Future Perspectives

open access: yesMedComm, Volume 7, Issue 7, July 2026.
Intratumoral bacteria are emerging as active regulators of cancer evolution rather than bystanders. This review outlines how tumor‐resident microbes drive tumor initiation and growth by inducing genomic instability, epigenetic reprogramming, oncogenic signaling, and chronic inflammation, while promoting metastatic spread via invasion, angiogenesis ...
Jiawei Chen   +6 more
wiley   +1 more source

The aryl hydrocarbon receptor repressor

open access: yes, 2008
Peer ...
Zudaire, Enrique   +12 more
openaire   +1 more source

Urologic Bacteriome: The Hero or the Villain in Prostate Cancer Onset, Progression, and Treatment?

open access: yesMedicinal Research Reviews, Volume 46, Issue 4, Page 1111-1151, July 2026.
ABSTRACT Prostate cancer (PCa) is the second most frequently diagnosed cancer in men worldwide and the fifth leading cause of cancer‐related mortality, presenting urgent unmet clinical needs in diagnosis and treatment. The recognition of the microbiome as a key factor in human health has prompted numerous studies, revealing an exciting new approach to ...
Lara R. S. Fonseca   +6 more
wiley   +1 more source

Oxidative Stress Induced Senescent Macrophage‐Driven Squamous Cell Carcinoma Invasion via Glutamine Metabolic Reprogramming

open access: yesAging Cell, Volume 25, Issue 7, July 2026.
Oxidative stress induces GLS2‐dependent IL‐1β secretion in senescent macrophages, promoting SCC invasion through the IL‐1β/IL‐1R2 axis. Targeting IL‐1β suppresses invasion more effectively than GLS2 inhibition, highlighting a potential therapeutic strategy for SCC.
Shimeng Wang   +7 more
wiley   +1 more source

Safety and Biodistribution of Topical Laquinimod, an Immunomodulator Targeting Aryl Hydrocarbon Receptor: The LION Study. [PDF]

open access: yesOphthalmol Sci
El Feky D   +23 more
europepmc   +1 more source

Cytochrome P450 1a (CYP1A)‐Knockout Javanese Medaka Fish Exhibit Diabetic Traits and Reduced Reproductive Capacity

open access: yesThe FASEB Journal, Volume 40, Issue 12, 30 June 2026.
Analyses of cytochrome P450 1a (CYP1A)‐knockout (KO) Javanese medaka (Oryzias javanicus) revealed that CYP1A is involved in glucose regulation and reproduction. In the KO fish, significant increases in hepatic transcripts of insulin, glucagon, and somatostatin genes, as well as elevated blood glucose, liver mass, and liver triglyceride levels ...
Suhaila Rusni   +10 more
wiley   +1 more source

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