Results 131 to 140 of about 33,160 (231)
Tryptophan Metabolism and Aryl-Hydrocarbon Receptor Agonists in the Gut Microbiome of People With Myalgic Encephalomyelitis/Chronic Fatigue Syndrome. [PDF]
Esteban DJ +5 more
europepmc +1 more source
Intratumoral Microbiota in Tumor: Current Understandings and Future Perspectives
Intratumoral bacteria are emerging as active regulators of cancer evolution rather than bystanders. This review outlines how tumor‐resident microbes drive tumor initiation and growth by inducing genomic instability, epigenetic reprogramming, oncogenic signaling, and chronic inflammation, while promoting metastatic spread via invasion, angiogenesis ...
Jiawei Chen +6 more
wiley +1 more source
Extracellular ATP drives tryptophan metabolism and aryl hydrocarbon receptor activation to promote cellular senescence. [PDF]
Volonte D +3 more
europepmc +1 more source
The aryl hydrocarbon receptor repressor
Peer ...
Zudaire, Enrique +12 more
openaire +1 more source
Urologic Bacteriome: The Hero or the Villain in Prostate Cancer Onset, Progression, and Treatment?
ABSTRACT Prostate cancer (PCa) is the second most frequently diagnosed cancer in men worldwide and the fifth leading cause of cancer‐related mortality, presenting urgent unmet clinical needs in diagnosis and treatment. The recognition of the microbiome as a key factor in human health has prompted numerous studies, revealing an exciting new approach to ...
Lara R. S. Fonseca +6 more
wiley +1 more source
The role of the aryl hydrocarbon receptor in ovarian development, function, xenobiotic metabolism, and disease†. [PDF]
Dean AE, Flaws JA.
europepmc +1 more source
Oxidative stress induces GLS2‐dependent IL‐1β secretion in senescent macrophages, promoting SCC invasion through the IL‐1β/IL‐1R2 axis. Targeting IL‐1β suppresses invasion more effectively than GLS2 inhibition, highlighting a potential therapeutic strategy for SCC.
Shimeng Wang +7 more
wiley +1 more source
Safety and Biodistribution of Topical Laquinimod, an Immunomodulator Targeting Aryl Hydrocarbon Receptor: The LION Study. [PDF]
El Feky D +23 more
europepmc +1 more source
Analyses of cytochrome P450 1a (CYP1A)‐knockout (KO) Javanese medaka (Oryzias javanicus) revealed that CYP1A is involved in glucose regulation and reproduction. In the KO fish, significant increases in hepatic transcripts of insulin, glucagon, and somatostatin genes, as well as elevated blood glucose, liver mass, and liver triglyceride levels ...
Suhaila Rusni +10 more
wiley +1 more source

