Results 151 to 160 of about 33,261 (251)
Aryl hydrocarbon receptor in the kidney regulates metabolic cross-talk with the liver and gut microbiome. [PDF]
Jamshidi N, Nigam SK.
europepmc +1 more source
Environmental toxicants may disrupt developmental pathways via strong molecular docking interactions with hub FGF proteins (FGF9 and FGF4) like dibenzo‐p‐dioxin (−7.2 kcal/mol) at the ASN146 residue of FGF9, driving congenital malformations as revealed by PPI networks and toxicity profiling.
Adarsh Kumar Shukla +3 more
wiley +1 more source
Combination of Chromatographic and Machine Learning-Driven Virtual Fractionation Identifies Aryl Hydrocarbon Receptor Agonists in Sediments. [PDF]
Wang H +5 more
europepmc +1 more source
Bio‐derived lignin–Eosin Y macromolecular networks are developed as visible‐light‐responsive self‐sterilizing coatings that generate reactive oxygen species without leaching. The spray‐coated photopolymerized surfaces exhibit durable antibacterial and antiviral activity under ambient light for extended periods, demonstrating a scalable and sustainable ...
Euna Oh +7 more
wiley +1 more source
IBD risk locus rs1077773 enhances aryl hydrocarbon receptor activity and modulates immune cell function in vitro. [PDF]
King AC +4 more
europepmc +1 more source
The Dual Role of the Gut Microbiota in Cancer Chemoresistance
Comparison between Microbiota and Cancer therapy. ABSTRACT Chemoresistance is one of the primary reasons that cancer chemotherapy fails to deliver successful treatment outcomes and contributes to poor overall survival rates for patients with cancer. New research has begun to shed light on the effects of the gut microbiome (GM).
Hamed Tahmasebi +3 more
wiley +1 more source
Circadian tryptophan metabolism contributes to systemic aryl hydrocarbon receptor activity. [PDF]
Morgan EW +4 more
europepmc +1 more source
ABSTRACT Excessive activation of the estrogen receptor (ER) drives proliferation, progression, and the formation of breast cancer stem cells (CSCs) in ER‐positive breast cancer. Estrogenic endocrine disrupting compounds (EDCs) found in plastics, water, and food are also able to bind to the ER.
Cassandra Winz +9 more
wiley +1 more source
Drug-Induced Glucose Metabolism Disorders: Role of Aryl Hydrocarbon Receptor. [PDF]
Grishanova AY, Perepechaeva ML.
europepmc +1 more source
SIRT Family: Biological Functions and Therapeutic Targets
SIRT1–SIRT7 networks from transgenic mice to human‑relevant therapeutic targets. SIRT1–SIRT7 form an isoform‑, organ‑, and disease‑specific regulatory network. Transgenic Sirt1–7 mouse models define central regulatory SIRTs (SIRT1, SIRT3, SIRT6), context‑dependent modifiers (SIRT2, SIRT4, SIRT5, SIRT7), and their key mechanisms and target organs. These
Jia‐Yi Wang +9 more
wiley +1 more source

