Results 171 to 180 of about 1,983,941 (246)

Structure-activity relationships among mono- and dihydroxy flavones as aryl hydrocarbon receptor (AhR) agonists or antagonists in CACO2 cells. [PDF]

Chem Biol Interact, 2022
Park H, Jin UH, Martin G, Chapkin RS, Davidson LA, Lee K, Jayaraman A, Safe S.   +7 more
europepmc   +1 more source

Lachnospiraceae in the Food–Gut Axis: A Critical Review of Dietary Modulation, Immune Regulation, and Translational Barriers

Comprehensive Reviews in Food Science and Food Safety, Volume 25, Issue 6, November 2026.
ABSTRACT The interplay between diet, gut microbiota, and host immunity is central to food science. The Lachnospiraceae family ferments dietary fibers to produce short‐chain fatty acids (SCFAs), notably butyrate and propionate, with immunomodulatory potential. This critical review distinguishes established findings from hypotheses.
Ruijun Wang, Zhiqi Li, Lina Zhang, Yuanming Pan, Zhanbiao He   +4 more
wiley   +1 more source

Oral Butyrate Reduces Progression of Kidney Damage in an L‐NAME‐Induced Diabetic Kidney Disease Mouse Model

Diabetes, Obesity and Metabolism, Volume 28, Issue 11, Page 10278-10291, November 2026.
ABSTRACT Aims Diabetic kidney disease (DKD) is one of the main causes of kidney failure worldwide. Interestingly, patients affected by DKD are characterised by a low abundance of gut bacteria producing short fatty acids including butyrate, which is suggested to play a role in the decline of renal function.
Maria Novella Nicese, Angela Koudijs, Reshma Lalai, Cristina Avramut, Rico J. E. Derks, Elena Sánchez‐López, Martin Giera, Amanda C. M. Pronk, Artemiy Kovynev, Sander Kooijman, Patrick C. N. Rensen, Roel Bijkerk, Bernard M. van den Berg, Joris I. Rotmans   +13 more
wiley   +1 more source

Aryl hydrocarbon receptor (AhR) regulates organic dust and organic dust-associated bacterial extracellular vesicles-induced airway inflammation via ROS-dependent NFκB and STAT3 activation. [PDF]

Respir Res
Meganathan V, Kusampudi S, Stenhouse M, Boggaram V.   +3 more
europepmc   +1 more source

Endogenous regulation of the Akt pathway by the aryl hydrocarbon receptor (AhR) in lung fibroblasts. [PDF]

Sci Rep, 2021
Shi F, Aloufi N, Traboulsi H, Trempe JF, Eidelman DH, Baglole CJ.   +5 more
europepmc   +1 more source

The Cutaneous Melatoninergic System: Endogenous Biology and Potential for Therapeutic Targeting

Experimental Dermatology, Volume 35, Issue 11, November 2026.
ABSTRACT Melatonin is best known as a pineal hormone that regulates circadian rhythms, but the skin also possesses an intrinsic melatoninergic system capable of local synthesis, metabolism and signalling. This system encompasses classical melatonin receptors, biologically active metabolites, non‐classical signalling pathways and receptor‐independent ...
Ju Hee Han, Hei Sung Kim
wiley   +1 more source

The aryl hydrocarbon receptor (AHR) drives human leukocyte antigen (HLA)-II expression in human melanoma. [PDF]

J Exp Clin Cancer Res
Jin Y, Zheng W, Zhang R, Hou S, Luo C, Ren P, Pan D, Luo C, Zeng Z.   +8 more
europepmc   +1 more source

Investigation of the role of CyP40 in the aryl hydrocarbon receptor signaling pathway

, 2008
Cyclophilin-40 (CyP40) promotes the formation of the gel shift complex containing baculovirus aryl hydrocarbon receptor (AhR), AhR nuclear translocator (Arnt) and dioxin response element (DRE).
Luu, Tony C.
core  

Iodized Garlic Extract Regulates Stress Responses in Epidermal Keratinocytes via the Transcription Factor Nrf2

Journal of Cosmetic Dermatology, Volume 25, Issue 11, November 2026.
ABSTRACT Objective Garlic exerts protective effects against skin stress, including oxidative damage and trauma. Iodized garlic extract (IGEx) is a cosmetic ingredient developed through iodination of garlic odor components to achieve odor reduction. Although IGEx is expected to exhibit skin stress protection properties similar to garlic, the molecular ...
Yuki Miyauchi, Natsumi Iwasaki, Liangjing Xie, Satoshi Yano, Taichi Hara   +4 more
wiley   +1 more source

Expression of the aryl hydrocarbon receptor (AhR) in facial melasma skin compared to healthy perilesional skin. [PDF]

An Bras Dermatol
da Silva CN, Grassi TF, Miot HA, Espósito ACC.   +3 more
europepmc   +1 more source