Results 151 to 160 of about 17,285 (228)

Paclitaxel (Taxol) Inhibits the Arylamine N‐Acetyltransferase Activity and Gene Expression (mRNA NAT1) and 2‐Aminofluorene‐DNA Adduct Formation in Human Bladder Carcinoma Cells (T24 and TSGH 8301) [PDF]

, 2003
Ching‐Chiang Yang, Guang‐Wei Chen, Hsueh‐Fu Lu, Der‐Yuan Wang, Yi‐Shuan Chen, Jing‐Gung Chung   +5 more
openalex   +1 more source

Peroxynitrite Irreversibly Inactivates the Human Xenobioticmetabolizing Enzyme Arylamine N-Acetyltransferase 1 (NAT1) in Human Breast Cancer Cells [PDF]

, 2004
Julien Dairou, Noureddine Atmane, Fernando Rodrigues‐Lima, Jean‐Marie Dupret   +3 more
openalex   +1 more source

Expression, purification, characterization and structure of Pseudomonas aeruginosa arylamine N-acetyltransferase [PDF]

, 2005
Isaac M. Westwood, Simon J. Holton, Fernando Rodrigues‐Lima, Jean‐Marie Dupret, Sanjib Bhakta, M.E.M. Noble, Edith Sim   +6 more
openalex   +1 more source

Polymorphisms of arylamine N-acetyltransferase2 and risk of lung and colorectal cancer

Genetics and Molecular Biology, 2012
The arylamine N-acetyltransferase 2 (NAT2) enzymes detoxify a wide range of naturally occurring xenobiotics including carcinogens and drugs. Point mutations in the NAT2 gene result in the variant alleles M1 (NAT2 *5A), M2 (NAT2*6A), M3 (NAT2*7) and M4 ...
Amjad Mahasneh, Amal Jubaili, Ahmed El Bateiha, Mohammad Al-Ghazo, Ismail Matalka, Mousa Malkawi   +5 more
doaj  

Pharmacogenomic heterogeneity of N-acetyltransferase 2: a comprehensive analysis of real world data in Indian tuberculosis patients and from literature and database review

Annals of Medicine
Background Isoniazid is primarily metabolized by the arylamine N-acetyltransferase 2 (NAT2) enzyme. Single nucleotide polymorphisms (SNPs) in the NAT2 gene could classify an individual into three distinct phenotypes: rapid, intermediate and slow ...
Levin Thomas, Chaithra, Yashi Batra, Mitali Mathur, Shrivathsa Kulavalli, Chidananda Sanju SV, Naveen Dutt, Pankaj Bhardwaj, Muralidhar Varma, Kavitha Saravu, Mithu Banerjee, Mahadev Rao   +11 more
doaj   +1 more source

N-hydroxyarylamine O-acetyltransferase of Salmonella typhimurium: proposal for a common catalytic mechanism of arylamine acetyltransferase enzymes.

, 1994
Maiko Watanabe, Tamotsu IGARASHI, Tsuguchika Kaminuma, Toshio Sofuni, T. Nohmi   +4 more
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Binding of the anti‐tubercular drug isoniazid to the arylamine N‐acetyltransferase protein from Mycobacterium smegmatis [PDF]

, 2005
James Sandy, Simon J. Holton, Elizabeth Fullam, Edith Sim, M.E.M. Noble   +4 more
openalex   +1 more source

Cloning and expression of cDNAs for polymorphic and monomorphic arylamine N-acetyltransferases from human liver.

, 1990
Shunji Ohsako, Takao Deguchi
openalex   +1 more source

Computational and Experimental Analyses of Mammalian ArylamineN-Acetyltransferase Structure and Function [PDF]

, 2007
Jason M. Walraven, John O. Trent, David W. Hein   +2 more
openalex   +1 more source

Probing the catalytic potential of the hamster arylamine N‐acetyltransferase 2 catalytic triad by site‐directed mutagenesis of the proximal conserved residue, Tyr190 [PDF]

, 2009
Xin Zhou, Naixia Zhang, Li Liu, Kylie J. Walters, Patrick E. Hanna, Carston R. Wagner   +5 more
openalex   +1 more source