Results 101 to 110 of about 1,089 (172)

Multitarget-Directed Ligands Hitting Serotonin Receptors: A Medicinal Chemistry Survey. [PDF]

Pharmaceuticals (Basel)
Ghafir El Idrissi I, Santo A, Lacivita E, Leopoldo M.   +3 more
europepmc   +1 more source

The structure of the dopamine D₃ receptor bound to cariprazine reveals principles for partial agonists with designed pharmacology. [PDF]

Sci Adv
Hadas Yardeni E, Kiss DJ, Sanchez J, Shavit K, Szepesi Kovács D, Egyed A, Vogt CD, Gaitonde SA, Glenn J, Canals M, Bouvier M, Newman AH, Lane JR, Keserű GM, Shalev-Benami M.   +14 more
europepmc   +1 more source

Novel Multimodal Salicylamide Derivative with Antidepressant-like, Anxiolytic-like, Antipsychotic-like, and Anti-Amnesic Activity in Mice. [PDF]

Pharmaceuticals (Basel), 2023
Żmudzka E, Lustyk K, Głuch-Lutwin M, Wolak M, Jaśkowska J, Kołaczkowski M, Sapa J, Pytka K.   +7 more
europepmc   +1 more source

Synthesis of arylpiperazine substituted bisindolylmethanes as possible pharmacologically active new compounds

ARKIVOC, 2018
Busra Arvas, Omer Tahir Gunkara, Nuket Ocal   +2 more
doaj   +1 more source

Recent advances in the synthesis of antidepressant derivatives: pharmacologic insights for mood disorders. [PDF]

3 Biotech
Gupta JK, Singh K, Bhatt A, Porwal P, Rani R, Dubey A, Jain D, Rai SN.   +7 more
europepmc   +1 more source

Bioisosteric Replacement of Amides with 1,2,3-Triazoles Improves Dopamine D4 Receptor Ligand Pharmacokinetics. [PDF]

ACS Pharmacol Transl Sci
Alkhatib M, Jakobs FM, Hanson JN, Nilson AN, Moritz AE, Li T, Faibille AB, Bourn LA, Ramdhan PA, Ricchezza J, Jordan S, Panasis D, Nguyen N, Kasarla N, Wang B, Garcia SS, Saez J, Paule J, Lee CB, Rais R, Slusher BS, Sibley DR, Li C, Keck TM, Boateng CA.   +24 more
europepmc   +1 more source

Development of heterocyclic-based frameworks as potential scaffold of 5-HT1A receptor agonist and future perspectives: A review. [PDF]

Medicine (Baltimore)
Yuan W, Ma Y, Zhang H.
europepmc   +1 more source

Design, synthesis, and biological evaluation of N-arylpiperazine derivatives as interferon inducers. [PDF]

Bioorg Med Chem Lett, 2020
Chu Y, Raja Sekhara Reddy B, Pratap Reddy Gajulapalli V, Sudhakar Babu K, Kim E, Lee S.   +5 more
europepmc   +1 more source

Anti-Inflammatory Properties of Novel 1,2-Benzothiazine Derivatives and Their Interaction with Phospholipid Model Membranes. [PDF]

Membranes (Basel)
Szczęśniak-Sięga BM, Maniewska J, Wiatrak B, Janek T, Nowotarska P, Czyżnikowska Ż.   +5 more
europepmc   +1 more source

Targeting Dysregulated Lipid Metabolism in Cancer with Pharmacological Inhibitors. [PDF]

Cancers (Basel)
Gupta A, Das D, Taneja R.
europepmc   +1 more source