Results 81 to 90 of about 1,089 (172)

Data for: Synthesis and pharmacological evaluation of novel arylpiperazine oxicams derivatives as potent analgesics without ulcerogenicity

, 2019
Data for: Synthesis and pharmacological evaluation of novel arylpiperazine oxicams derivatives as potent analgesics without ulcerogenicityTHIS DATASET IS ARCHIVED AT DANS/EASY, BUT NOT ACCESSIBLE HERE. TO VIEW A LIST OF FILES AND ACCESS THE FILES IN THIS
Szczęśniak-Sięga, B (via Mendeley Data)
core   +1 more source

Novel Arylpiperazine Derivatives of Salicylamide with α₁-Adrenolytic Properties Showed Antiarrhythmic and Hypotensive Properties in Rats. [PDF]

Int J Mol Sci, 2022
Żmudzka E, Lustyk K, Siwek A, Wolak M, Gałuszka A, Jaśkowska J, Kołaczkowski M, Sapa J, Pytka K.   +8 more
europepmc   +1 more source

Design and synthesis of 5-aryl-4-(4-arylpiperazine-1-carbonyl)-2H-1,2,3-triazole derivatives as colchicine binding site inhibitors

, 2017
A series of 5-aryl-4-(4-arylpiperazine-1-carbonyl)-2H-1,2,3-triazol derivatives were designed as potential microtubule targeting agents. The regioselective alkylation of 5-aryl-4-(4-arylpiperazine-1-carbonyl)-2H-1,2,3-triazole was predicted by ...
Kai Bao, Peng Yan, Weige Zhang, Daiying Zuo, Qi Guan, Yue Wu, Meiqi Gao, Zhiwei Wang, Jun Sun, Yingliang Wu, Dongjie Feng, Zhenzhen Gu   +11 more
core   +1 more source

Design, Synthesis and Biological Evaluation of Novel N-Arylpiperazines Containing a 4,5-Dihydrothiazole Ring. [PDF]

Pharmaceuticals (Basel), 2023
Andreozzi G, Ambrosio MR, Magli E, Maneli G, Severino B, Corvino A, Sparaco R, Perissutti E, Frecentese F, Santagada V, Leśniak A, Bujalska-Zadrożny M, Caliendo G, Formisano P, Fiorino F.   +14 more
europepmc   +1 more source

A chemometric study of the 5-HT1A receptor affinities presented by arylpiperazine compounds

, 2008
Arylpiperazine compounds are promising 5-HT1A receptor ligands that can contribute for accelerating the onset of therapeutic effect of selective serotonin reuptake inhibitors. In the present work, the chemometric methods HCA, PCA, KNN, SIMCA and PLS were
WEBER, Karen C., SILVA, Alberico B. F. da   +1 more
core   +1 more source

Molecular Research on Mental Disorders. [PDF]

Int J Mol Sci, 2023
Sowa-Kućma M, Stachowicz K.
europepmc   +1 more source

Imidazoles as Serotonin Receptor Modulators for Treatment of Depression: Structural Insights and Structure-Activity Relationship Studies. [PDF]

Pharmaceutics, 2023
Goel KK, Thapliyal S, Kharb R, Joshi G, Negi A, Kumar B.   +5 more
europepmc   +1 more source

Modeling interactions of alpha(1a) adrenergic receptor and different arylpiperazine ligands

, 2012
Molecular modelling studies were undertaken in order to identify key interactions of selected ligands with alpha(1A) adrenergic receptor, responsible for their binding and presumably receptor activation.
Senćanski, Milan V., Andrić, Deana, Kostić Rajačić, Slađana, Šukalović, Vladimir, Došen-Mićović, Ljiljana, Šoškić, Vukić, Roglić, Goran   +6 more
core   +3 more sources

Potential Anti-Amnesic Activity of a Novel Multimodal Derivative of Salicylamide, JJGW08, in Mice. [PDF]

Pharmaceuticals (Basel), 2023
Żmudzka E, Lustyk K, Sałaciak K, Siwek A, Jaśkowska J, Kołaczkowski M, Sapa J, Pytka K.   +7 more
europepmc   +1 more source

Antipsychotic- and Anxiolytic-like Properties of a Multimodal Compound JJGW08 in Rodents. [PDF]

Int J Mol Sci, 2022
Żmudzka E, Lustyk K, Głuch-Lutwin M, Mordyl B, Zakrzewska-Sito A, Mierzejewski P, Jaśkowska J, Kołaczkowski M, Sapa J, Pytka K.   +9 more
europepmc   +1 more source