Results 51 to 60 of about 1,055 (154)

Design, Synthesis and Pharmacological Evaluation of Novel Conformationally Restricted N-arylpiperazine Derivatives Characterized as D₂/D₃ Receptor Ligands, Candidates for the Treatment of Neurodegenerative Diseases. [PDF]

Biomolecules, 2022
da Silva Cunha TT, Silva RR, Rodrigues DA, de Sena Murteira Pinheiro P, Kronenberger T, Sant'Anna CMR, Noël F, Fraga CAM.   +7 more
europepmc   +1 more source

MOESM1 of Structural determinants influencing halogen bonding: a case study on azinesulfonamide analogs of aripiprazole as 5-HT1A, 5-HT7, and D2 receptor ligands

, 2018
Additional file 1: Figure S1. Histograms of population of different arylpiperazine salts conformations. Figure S2. Low-energy conformation of the studied compounds in aqueous medium. Table S1. Conformation of arylpiperazine derivatives with polymethylene
Maria Książek (5205656), Rafał Kurczab (1312479), Paweł Zajdel (2606617), Elwira Chrobak (5205659), Krzysztof Marciniec (2606629), Ewa Bębenek (5205653), Grzegorz Satała (805228), Joachim Kusz (2243047), Andrzej Bojarski (3761443)   +8 more
core   +1 more source

Potential Anti-Amnesic Activity of a Novel Multimodal Derivative of Salicylamide, JJGW08, in Mice. [PDF]

Pharmaceuticals (Basel), 2023
Żmudzka E, Lustyk K, Sałaciak K, Siwek A, Jaśkowska J, Kołaczkowski M, Sapa J, Pytka K.   +7 more
europepmc   +1 more source

Antipsychotic- and Anxiolytic-like Properties of a Multimodal Compound JJGW08 in Rodents. [PDF]

Int J Mol Sci, 2022
Żmudzka E, Lustyk K, Głuch-Lutwin M, Mordyl B, Zakrzewska-Sito A, Mierzejewski P, Jaśkowska J, Kołaczkowski M, Sapa J, Pytka K.   +9 more
europepmc   +1 more source

A synthethic overview of new molecules with 5-HT 1A binding affinities [PDF]

, 2003
The present review discusses the synthetic strategies of new ligands exhibiting mainly 5-HT1A binding affinities. Specifically we focused our attention in the synthesis of compounds structurally telated to arylpiperazine, 2-aminotetralin, and benzopyran ...
Saitz Barría, Claudio, Pessoa, D., Pessoa Mahana, Hernán, Araya Maturana, Ramiro   +3 more
core  

Design Strategies, Chemistry and Therapeutic Insights of Multi-target Directed Ligands as Antidepressant Agents. [PDF]

Curr Neuropharmacol, 2022
Singh K, Bhatia R, Kumar B, Singh G, Monga V.   +4 more
europepmc   +1 more source

Editorial: Advances in green synthesis for drug discovery. [PDF]

Front Chem, 2023
Allais F, Brogi S, Castro GR, Vidali VP.
europepmc   +1 more source

JSCS–3899

, 2009
The influence of dispersive interactions on the binding affinities of ligands with an arylpiperazine moiety to the dopamine D2 ...
Vladimir V. Šukalović, Deana B. Andrić, Goran M. Roglić, Mario V. Zlatović, Slađana V. Kostić-rajačić   +4 more
core  

Dopamine D3 receptor ligand suppresses the expression of levodopa-induced dyskinesia in nonhuman primate model of parkinson's disease. [PDF]

Exp Neurol, 2022
Oh T, Daadi ES, Kim J, Daadi EW, Chen PJ, Roy-Choudhury G, Bohmann J, Blass BE, Daadi MM.   +8 more
europepmc   +1 more source

Pharmacology and Therapeutic Potential of Benzothiazole Analogues for Cocaine Use Disorder. [PDF]

J Med Chem, 2023
Boateng CA, Nilson AN, Placide R, Pham ML, Jakobs FM, Boldizsar N, McIntosh S, Stallings LS, Korankyi IV, Kelshikar S, Shah N, Panasis D, Muccilli A, Ladik M, Maslonka B, McBride C, Sanchez MX, Akca E, Alkhatib M, Saez J, Nguyen C, Kurtyan E, DePierro J, Crowthers R, Brunt D, Bonifazi A, Newman AH, Rais R, Slusher BS, Free RB, Sibley DR, Stewart KD, Wu C, Hemby SE, Keck TM.   +34 more
europepmc   +1 more source