Results 1 to 10 of about 14,004 (249)

A closer look at ARSA activity in a patient with metachromatic leukodystrophy [PDF]

open access: yesMolecular Genetics and Metabolism Reports, 2019
Metachromatic leukodystrophy (MLD) is an autosomal recessive lysosomal storage disease mainly caused by a deficiency of arylsulfatase A activity. The typical clinical course of patients with the late infantile form includes a regression in motor skills ...
Kathleen Doherty   +6 more
doaj   +3 more sources

Structural insights into manganese-dependent arylsulfatase from Enterococcus faecium and its catalytic promiscuity [PDF]

open access: yesmBio
Catalytic promiscuity, wherein enzymes catalyze multiple distinct reactions by stabilizing various transition states, is well documented in the alkaline phosphatase superfamily.
Lulu Guo   +9 more
doaj   +2 more sources

Optimisation of culture conditions for a producer clone coexpressing arylsulfatase B and a formylglycine-generating enzyme in order to increase the yield of arylsulfatase B

open access: diamondБиопрепараты: Профилактика, диагностика, лечение, 2022
Maroteaux—Lamy syndrome (mucopolysaccharidosis type VI) is an orphan genetic disease caused by mutations in the arylsulfatase B gene (ARSB), which encodes the lysosomal enzyme arylsulfatase B (ASB).
S. S. Timonova   +7 more
doaj   +3 more sources

Exploring the Venom Gland Transcriptome of Bothrops asper and Bothrops jararaca: De Novo Assembly and Analysis of Novel Toxic Proteins [PDF]

open access: yesToxins
Previous proteomic studies of viperid venom revealed that it is mainly composed of metalloproteinases (SVMPs), serine proteinases (SVSPs), phospholipase A2 (PLA2), and C-type lectins (CTLs).
Joseph Espín-Angulo, Doris Vela
doaj   +2 more sources

Arylsulfatase B improves locomotor function after mouse spinal cord injury. [PDF]

open access: goldPLoS ONE, 2013
Bacterial chondroitinase ABC (ChaseABC) has been used to remove the inhibitory chondroitin sulfate chains from chondroitin sulfate proteoglycans to improve regeneration after rodent spinal cord injury.
Myungsik Yoo   +6 more
doaj   +3 more sources

Arylsulfatase K attenuates airway epithelial cell senescence in COPD by regulating parkin-mediated mitophagy [PDF]

open access: yesRedox Biology
Chronic obstructive pulmonary disease (COPD) is a heterogeneous lung condition characterized by irreversible airflow limitation, primarily due to cigarette smoke (CS) exposure.
Ruonan Yang   +12 more
doaj   +2 more sources

Specific Fertilization Practices Reveal Important Insights into the Complex Interaction Between Microbes and Enzymes in Soils of Different Farming Systems [PDF]

open access: yesLife
The interaction of microorganisms and their enzyme activity is one of the key indicators for a comprehensive measurement of soil health. The aim of this study was to determine significant correlations between different soil microorganisms and enzyme ...
Maša Pintarič   +3 more
doaj   +2 more sources

Soil enzymatic activity and wheat grain yield under cover crop systems

open access: yesPesquisa Agropecuária Tropical, 2023
For years, the impacts of using cover crops in productive systems have been measured by their relation with soil chemical and physical characteristics. Consequently, the effects on the soil microbiological characteristics have been little explored.
Luís Felipe Rossetto Gerlach   +4 more
doaj   +1 more source

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