Results 1 to 10 of about 6,262 (165)
Structural insights into manganese-dependent arylsulfatase from Enterococcus faecium and its catalytic promiscuity [PDF]
mBioCatalytic promiscuity, wherein enzymes catalyze multiple distinct reactions by stabilizing various transition states, is well documented in the alkaline phosphatase superfamily.
Lulu Guo +9 more
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Arylsulfatase K attenuates airway epithelial cell senescence in COPD by regulating parkin-mediated mitophagy [PDF]
Redox BiologyChronic obstructive pulmonary disease (COPD) is a heterogeneous lung condition characterized by irreversible airflow limitation, primarily due to cigarette smoke (CS) exposure.
Ruonan Yang +12 more
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Arylsulfatase A pseudodeficiency incidence in Turkey
The Turkish Journal of Pediatrics, 2000 Pseudodeficiency (Pd) in arylsulfatase A (ASA) is a relatively frequent condition in healthy individuals. It produces a reduction in enzyme activity similar to that found in metachromatic leukodystrophy (MLD). A variable incidence of the Pd allele
S Emre, M Topçu, M Terzioğlu, Y Renda
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Adult metachromatic leukodystrophy: case report
Неврология, нейропсихиатрия, психосоматика, 2021 Metachromatic leukodystrophy (MLD) is a hereditary lysosomal storage disease inherited in an autosomal recessive pattern, which occurs across all age groups.
T. I. Prusova +3 more
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Pseudo arylsulfatase A deficiency Biosynthesis of an abnormal arylsulfatase A [PDF]
FEBS Letters, 1987 Pseudo arylsulfatase A deficiency, an asymptomatic condition, and metachromatic leukodystrophy, a severe neurodegenerative disease, are both associated with profound reductions of arylsulfatase A activity in man. We now report that with metabolic labelling, cultured pseudo deficient cells synthesized about 20% of the normal amount of arylsulfatase A at
Ameen, Mohammed, Chang, Patricia L.
openaire +2 more sources
Soil enzyme activities after application of fungicide QuadrisR at increasing concentration rates
Plant, Soil and Environment, 2022 The study aimed to assess the effects of fungicide QuadrisR on activities of soil enzymes contributed to soil nutrient turnover. A batch laboratory experiment with QuadrisR-amended (0 mg/kg ds (dry soil) - 35.00 mg/kg ds) loamy sand soil was conducted ...
Silvena Boteva Boteva +5 more
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JIMD Reports, 2022 Metachromatic leukodystrophy (MLD) is an autosomal recessive lysosomal storage disease caused by deficiency of arylsulfatase A (ARSA). Heterozygous carriers of disease‐causing variants and individuals harbouring pseudodeficiency alleles in the ARSA gene ...
Lucia Laugwitz +10 more
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Arylsulfatase A pseudodeficiency in healthy Brazilian individuals
Brazilian Journal of Medical and Biological Research, 1999 Molecular alterations associated with arylsulfatase A pseudodeficiency (ASA-PD) were characterized by PCR and restriction endonuclease analysis in a sample of healthy individuals from Brazil. ASA activity was also assayed in all subjects. Two individuals
C.G. Pedron +3 more
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Metachromatic leukodystrophy: A case report
Bangabandhu Sheikh Mujib Medical University Journal, 2016 Metachromatic leuk:odystrophy (MLD) is a rare neurometabolic disease caused by the deficiency of the enzyme arylsulfatase A .Deficiency of this enzyme results in intralysosomal storage ofsphingolipid , cerebroside 3-sulfates (sulfatides), which are ...
Gopen Kumar Kundu +2 more
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Infantile Metachromatic Leukodystrophy: Case Report
Case Reports in Clinical Practice, 2023 Metachromatic Leukodystrophy (MLD) is commonly characterized by the accumulation of sulfatide in various organs, including the central nervous system, leading to neurological and mental symptoms.
Salsabeel Hamad +4 more
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