Results 31 to 40 of about 6,281 (181)
Agronomy, 2021 A number of agriculture residues may be used either directly or after suitable treatment as amendments to improve soil quality. Such materials include biochar made of agriculture residues, digestate or elemental sulphur obtained from biogas ...
Tereza Hammerschmiedt +9 more
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Localization of arylsulfatase in Pseudomonas C12B [PDF]
Applied and Environmental Microbiology, 1977 Arylsulfatase was released almost completely from intact cells of Pseudomonas C12B after osmotic shock or after treatment with lysozyme. These results suggest that the enzyme is cell wall associated in this soil isolate.
J W, Fitzgerald, J R, George
openaire +2 more sources
Molecular Basis of Metachromatic Leukodystrophies
Pediatric Neurology Briefs, 1991 Arylsulfatase A alleles were analyzed in 68 patients with metachromatic leukodystrophy in the Department of Biochemistry II, Georg-August-Universitat Gottingen, Gosslerstr, Gottingen, Germany.
J Gordon Millichap
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Chemical Metabolomics: Chemical Biology Tools for Advanced Metabolism Investigations
Angewandte Chemie, Volume 138, Issue 23, 1 June 2026.The human metabolism has been investigated for several millennia. The metabolome is known for a high complexity due to a large number of different metabolites that are present at different concentrations. Metabolomics has been developed as a field to investigate the entire human metabolome and to elucidate disease development mechanisms.
Alejandro Torregrosa‐Chinillach +4 more
wiley +2 more sources
Central Precocious Puberty in a Child With Metachromatic Leukodystrophy
Frontiers in Endocrinology, 2018 Metachromatic leucodystrophy (MLD) is a rare inherited lysosomal disorder caused by reduced activity of the enzyme arylsulfatase A with accumulation of sulfatides in the nervous system.
Gilda Belli +6 more
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Endogenous melatonin partial metabolic clearance as a potential endogenous marker of CYP1A2 activity
British Journal of Clinical Pharmacology, EarlyView.Aims Cytochrome P450 1A2 (CYP1A2) exhibits substantial interindividual variability, necessitating appropriate phenotyping strategies for personalized pharmacotherapy. This study evaluated endogenous melatonin partial metabolic clearance (CLm(MEL)), calculated from urinary 6‐hydroxymelatonin (6‐O‐MEL) excretion and plasma melatonin (MEL) exposure, as a ...
Akitomo Yokokawa +5 more
wiley +1 more source
Enzymatic Activity in Different Crop Succession Systems in the Cerrado Region
AgronomyThe enzymatic activity of soil arylsulfatase and β-glucosidase enzymes are biological parameters used to measure the biological activity of soils, an important tool for identifying disturbances in agricultural systems, as they are more sensitive to ...
Vanessa Brenda Souza Chaves +4 more
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Ocular Manifestation in a Rare Case of Mucopolysaccharidosis VI
Journal of Mazandaran University of Medical Sciences, 2021 Mucopolysaccharidosis VI is an inherited autosomal recessive disease that causes glycosaminoglycan deposition in different tissues due to arylsulfatase deficiency that can cause various systemic and ocular manifestations.
Leila Rezaei, Naser Aghaei
doaj
Molecular Genetics and Metabolism Reports, 2020 Metachromatic leukodystrophy (MLD) is a glycosphingolipid storage disease caused by deficiency of the lysosomal enzyme arylsulfatase A (ASA) or its activator protein saposin B. MLD can affect all age groups in severity varying from a severe fatal form to
Faruk Pekgül +12 more
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Nonclinical comparability studies of recombinant human arylsulfatase A addressing manufacturing process changes. [PDF]
PLoS ONE, 2018 Recombinant human arylsulfatase A (rhASA) is in clinical development for the treatment of patients with metachromatic leukodystrophy (MLD). Manufacturing process changes were introduced to improve robustness and efficiency, resulting in higher levels of ...
Teresa Wright +6 more
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